esculentoside H
- Product Name
- esculentoside H
- CAS No.
- 66656-92-6
- Chemical Name
- esculentoside H
- Synonyms
- esculentoside H;Phytolaccasaponin B;ESCULENTOSIDE H (ESH);4)-beta-D-xylopyranosyl)-28-beta-D-glucopyranosylphytolaccagenin;JNK,Inhibitor,Nuclear factor-kappaB,Esculentoside H,NF-κB,inhibit,Nuclear factor-κB;3-O-(O-beta-D-glucopyranosyl-(1-4)-beta-D-xylopyranosyl)-28-beta-D-glucopyranosylphytolaccagenin;Olean-12-ene-28,29-dioic acid, 3-[(4-O-β-D-glucopyranosyl-β-D-xylopyranosyl)oxy]-2,23-dihydroxy-, 28-β-D-glucopyranosyl 29-methyl ester, (2β,3β,4α,20β)-
- CBNumber
- CB71349884
- Molecular Formula
- C48H76O21
- Formula Weight
- 989.1
- MOL File
- 66656-92-6.mol
esculentoside H Property
- Boiling point:
- 1042.8±65.0 °C(Predicted)
- Density
- 1.48±0.1 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 12.52±0.70(Predicted)
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 300246
- Product name
- Esculentoside H
- Packaging
- 10mg
- Price
- $382
- Updated
- 2021/12/16
- Product number
- FE145235
- Product name
- Esculentoside H
- Packaging
- 2mg
- Price
- $81.26
- Updated
- 2021/12/16
- Product number
- CS-0019511
- Product name
- EsculentosideH
- Purity
- ≥98.0%
- Packaging
- 5mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FE145235
- Product name
- Esculentoside H
- Packaging
- 5mg
- Price
- $161.25
- Updated
- 2021/12/16
- Product number
- CS-0019511
- Product name
- EsculentosideH
- Purity
- ≥98.0%
- Packaging
- 10mg
- Price
- $250
- Updated
- 2021/12/16
esculentoside H Chemical Properties,Usage,Production
Uses
Esculentoside H (EsH) is a saponin isolated from the root extract of perennial plant Phytolacca esculenta[1]. Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease[2]. Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression[1].
References
[1] Ha SH, et al. Esculentoside H inhibits colon cancer cell migration and growth through suppression of MMP-9 gene expression via NF-kB signaling pathway. J Cell Biochem. 2019 Jun;120(6):9810-9819. DOI:10.1002/jcb.28261
[2] Hu ZL, et al. Effect of esculentoside H on release of tumor necrosis factor from mouse peritoneal macrophages. Zhongguo Yao Li Xue Bao. 1993 Nov;14(6):550-2. PMID:8010057
esculentoside H Preparation Products And Raw materials
Raw materials
Preparation Products
esculentoside H Suppliers
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View Lastest Price from esculentoside H manufacturers
- Product
- Esculentoside H 66656-92-6
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-03-24
- Product
- esculentoside H 66656-92-6
- Price
- US $8.00/KG
- Min. Order
- 1g
- Purity
- >98% HPLC
- Supply Ability
- kg--ton
- Release date
- 2020-02-20