4-Nitro-1H-indazole
Uses- Product Name
- 4-Nitro-1H-indazole
- CAS No.
- 2942-40-7
- Chemical Name
- 4-Nitro-1H-indazole
- Synonyms
- P-404;4-Nitroindazle;4-Nitroidazoles;4-NITROINDAZOLE;4-nitro-indazol;4-NITRO-1H-INDAZOLE;1H-Indazole, 4-nitro-
- CBNumber
- CB7135916
- Molecular Formula
- C7H5N3O2
- Formula Weight
- 163.13
- MOL File
- 2942-40-7.mol
4-Nitro-1H-indazole Property
- Melting point:
- 199-203°C
- Boiling point:
- 383.3±15.0 °C(Predicted)
- Density
- 1.525±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 11.08±0.40(Predicted)
- Appearance
- White to yellow Solid
- InChI
- InChI=1S/C7H5N3O2/c11-10(12)7-3-1-2-6-5(7)4-8-9-6/h1-4H,(H,8,9)
- InChIKey
- WBTVZVUYPVQEIF-UHFFFAOYSA-N
- SMILES
- N1C2=C(C([N+]([O-])=O)=CC=C2)C=N1
- CAS DataBase Reference
- 2942-40-7(CAS DataBase Reference)
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 2933998090
- Toxicity
- mouse,LD50,intravenous,320mg/kg (320mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03515,
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 285839
- Product name
- 4-Nitroindazole
- Packaging
- 500mg
- Price
- $368
- Updated
- 2021/12/16
- Product number
- 044531
- Product name
- 4-Nitro-1H-indazole
- Purity
- >95%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- OR110725
- Product name
- 4-Nitro-1H-indazole
- Packaging
- 5g
- Price
- $18
- Updated
- 2021/12/16
- Product number
- 4H55-1-64
- Product name
- 4-Nitro-1H-indazole
- Packaging
- 5G
- Price
- $20
- Updated
- 2021/12/16
- Product number
- 044531
- Product name
- 4-Nitro-1H-indazole
- Purity
- >95%
- Packaging
- 5g
- Price
- $33
- Updated
- 2021/12/16
4-Nitro-1H-indazole Chemical Properties,Usage,Production
Uses
4-Nitro-1H-indazole is a useful research chemical.
Chemical Properties
light yellow powder
Synthesis
603-83-8
2942-40-7
General procedure for the synthesis of 4-nitroindazole from 2-methyl-3-nitroaniline: A. Preparation of 4-nitroindazole An aqueous sodium nitrite solution was prepared by dissolving sodium nitrite (20 g, 0.29 mol) in 50 mL of water. This aqueous sodium nitrite solution was added at once to a glacial acetic acid solution containing 2-methyl-3-nitroaniline (20 g, 0.13 mol) at 0 °C. The reaction system was vigorously stirred using an overhead stirrer. Immediately after the addition of sodium nitrite solution, precipitation generation was observed. Subsequently, the reaction mixture was gradually warmed up to room temperature and stirring was continued overnight. Upon completion of the reaction, the precipitate was separated by filtration and the filtrate was concentrated under vacuum. The resulting dark orange solid was suspended in water, filtered again and dried to give 14-21 g of dark orange solid product in 99% yield.
References
[1] Patent: US6534504, 2003, B1
[2] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 11, p. 2752 - 2757
[3] Journal of Medicinal Chemistry, 2006, vol. 49, # 7, p. 2339 - 2352
[4] Organic Process Research and Development, 2007, vol. 11, # 3, p. 578 - 584
[5] Journal of Medicinal Chemistry, 2010, vol. 53, # 2, p. 649 - 659
4-Nitro-1H-indazole Preparation Products And Raw materials
Raw materials
Preparation Products
4-Nitro-1H-indazole Suppliers
- Tel
- +86-021-50890968，021-50891159 +86-18601776121
- Fax
- 086-21-68416099 58604179
- danny@urchem.com
- Country
- China
- ProdList
- 628
- Advantage
- 58
- Tel
- 0931-8235634 13321316780
- Fax
- +86(931) 4873122
- 1455540579@qq.com
- Country
- China
- ProdList
- 958
- Advantage
- 55
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- sales@jonln.com
- Country
- China
- ProdList
- 1995
- Advantage
- 65
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
View Lastest Price from 4-Nitro-1H-indazole manufacturers
- Product
- 4-Nitro-1H-indazole 2942-40-7
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-27
- Product
- 4-Nitro-1H-indazole 2942-40-7
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 50000tons
- Release date
- 2023-08-15
- Product
- 4-Nitro-1H-indazole 2942-40-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-09