5-Nitroindazole

Product Name: 5-Nitroindazole
CAS No.: 5401-94-5
Chemical Name: 5-Nitroindazole
Synonyms: 5-NITRO-1H-INDAZOLE;3-(METHYLAMINO)-1-PHENYLPROPAN-1-OL;3-METHYLAMINO-1-PHENYLPROPANOL;5-Nitroindazol;5-NITROINDAZOLE;5-Nitroindazoles;5-nitro-1h-indazol;5-Nitroindazole>1H-Indazole,5-nitro-;5-NITROINDAZOLE, 99+%
CBNumber: CB9706785
Molecular Formula: C7H5N3O2
Formula Weight: 163.13
MOL File: 5401-94-5.mol

More

Less

5-Nitroindazole Property

Melting point:: 207 °C
Boiling point:: 383.3±15.0 °C(Predicted)
Density: 1.525±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 11.71±0.40(Predicted)
form: powder to crystal
color: White to Light red to Green
BRN: 7936
InChI: InChI=1S/C7H5N3O2/c11-10(12)6-1-2-7-5(3-6)4-8-9-7/h1-4H,(H,8,9)
InChIKey: WSGURAYTCUVDQL-UHFFFAOYSA-N
SMILES: N1C2=C(C=C([N+]([O-])=O)C=C2)C=N1
CAS DataBase Reference: 5401-94-5(CAS DataBase Reference)
EPA Substance Registry System: 5-Nitroindazole (5401-94-5)

More

Less

Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38-68-36-20/21/22
Safety Statements: 26-36/37/39
WGK Germany: 2
RTECS: NK7962000
Hazard Note: Irritant
TSCA: Yes
HS Code: 29339990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: N0398
Product name: 5-Nitroindazole
Purity: >98.0%(GC)
Packaging: 25g
Price: $58
Updated: 2025/07/31

TRC

Product number: N496255
Product name: 5-Nitroindazole
Packaging: 100g
Price: $195
Updated: 2021/12/16

TRC

Product number: N496255
Product name: 5-Nitroindazole
Packaging: 50g
Price: $120
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H54-1-13
Product name: 5-Nitro-1H-indazole
Purity: 95%
Packaging: 100g
Price: $128
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK128335
Product name: 5-Nitroindazole
Purity: 98%
Packaging: 100g
Price: $92
Updated: 2021/12/16

More

Less

5-Nitroindazole Chemical Properties,Usage,Production

Chemical Properties

light yellow crystal

Uses

5-Nitroindazole inhibits citrulline formation by Ca2+-calmodulin (CaM)-dependent nitric oxide synthase from bovine brain. Nitration of 5-nitroindazole with nitric acid and acetic anhydride yields 3,5-dintroindazole and 2,5-dinitroindazole.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 21, p. 1063, 1984 DOI: 10.1002/jhet.5570210428
Organic Syntheses, Coll. Vol. 3, p. 660, 1955

Synthesis

27996-87-8

5401-94-5

General procedure: hydrazine hydrate (NH2NH2-H2O, 3.0 mmol) was added dropwise to a stirred solution of 2-fluoro-5-nitrobenzaldehyde (1.0 mmol) in DMF (5 mL) at 23 °C. The reaction mixture was stirred continuously at the same temperature for 2 h. The progress of the reaction was monitored by thin-layer chromatography (TLC, unfolding agent: 20% ethyl acetate in hexane solution) to confirm the complete conversion of the starting material 2-fluoro-5-nitrobenzaldehyde. Upon completion of the reaction, the crude reaction mixture was poured into water and extracted with ethyl acetate (2 x 15 mL). The organic phases were combined, washed sequentially with water and saturated aqueous sodium chloride, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give pure 5-nitroindazole.

References

[1] Molecules, 2018, vol. 23, # 3,
[2] Organic Process Research and Development, 2011, vol. 15, # 3, p. 565 - 569

5-Nitroindazole Preparation Products And Raw materials

Raw materials

2-Methyl-4-nitroaniline

Preparation Products

More

Less

5-Nitroindazole Suppliers

Americas 1 Belgium 2 China 287 Europe 3 Germany 7 India 31 Japan 7 Russia 1 Slovakia 1 Switzerland 3 The Netherlands 1 Ukraine 1 United Kingdom 20 United States 57 Global 422

Shandong Shining Medical Science and Technology Co., Ltd.

Tel: 18866891188
Email: xuandechem@126.com
Country: China
ProdList: 59
Advantage: 58

Shandong Xuanshuo Pharmaceutical Technology Co. LTD

Tel: 15269103900
Email: suchangzhou@shiningpharm.com
Country: China
ProdList: 330
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

More

Less

View Lastest Price from 5-Nitroindazole manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Nitroindazole 5401-94-5
Price: US $0.00/Kg/Bag
Min. Order: 1KG
Purity: 98%min
Supply Ability: 2500kg/month
Release date: 2021-06-04

Henan Aochuang Chemical Co.,Ltd.

Product: 5-Nitroindazole 5401-94-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-27

Anhui Ruihan Technology Co., Ltd

Product: 5-Nitroindazole 5401-94-5
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2023-09-08

5401-94-5, 5-NitroindazoleRelated Search:

4-Nitrobenzoic acid 3-Nitroacetophenone Nitroethane NITROGEN DIOXIDE 1-METHYL-5-NITROINDAZOLE 2-METHYL-5-NITRO-2H-INDAZOLE 3-Amino-5-nitroindazole 3-CHLORO-5-NITRO-1H-INDAZOLE Nitrobenzene TRITON 4-Nitrophenol Nitromethane 5-NITROINDAZOLE-3-CARBOXYLIC ACID 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE 6-Nitroindazole 3-BROMO-7-NITROINDAZOLE 3-IODO-6-NITROINDAZOLE 3-BROMO-5-NITROINDAZOLE

LABOTEST-BB LT00453610

5-NITROINDAZOLE

5-NITRO-1H-INDAZOLE

ALPHA-(2-METHYLAMINO)-ETHYLBENZENEMETHANOL

3-METHYLAMINO-1-PHENYL-1-PROPANOL

3-(METHYLAMINO)-1-PHENYLPROPAN-1-OL

3-METHYLAMINO-1-PHENYLPROPANOL

N-METHYL-3-HYDROXY-3-PHENYL PROPYLAMINE

N-METHYL-3-PHENYL-3-HYDROXYPROPYLAMINE

5-Nitroindazol

5-NITROINDAZOLE, 99+%

5-Nitroindazole, 98+%

5-NITRO-1H-INDAZOLE 99+%

5-Nitro-1H-indazole, 98+%

1H-Indazole,5-nitro-

5-nitro-1h-indazol

5-NITRO-1H-INDAZOLE FOR SYNTHESIS

5-Nitroindazoles

5-nitroindazole, 5-nitro-1H-indazole, 5-Nitroindazole, 5-nitro-indazole, 5-nitro-1(2)H-indazole, 5-Nitro-1(2)H-indazol, 5-nitro-1H-indazole

5-Nitroindazole&gt

5401-94-5 5-Nitroindazole

5401-94-5

C7H5N2O2

Amino Alcohols

Building Blocks

Heterocyclic Building Blocks

Indazoles

Organic Building Blocks

Oxygen Compounds

Fused Ring Systems

Building Blocks

Heterocyclic Building Blocks

(intermediate of fluoxetine hcl)

Indazoles

Indoles and derivatives

john's