6-Methoxy-2-naphthaldehyde

Product Name: 6-Methoxy-2-naphthaldehyde
CAS No.: 3453-33-6
Chemical Name: 6-Methoxy-2-naphthaldehyde
Synonyms: TIMTEC-BB SBB010060;Mitotane Impurity 17;LABOTEST-BB LT01147524;ASINEX-REAG BAS 07663025;6-Methoxy-2-Naphtaldehyde;6-Methoxy-2-napthaldehyde;6-METHOXY-2-NAPHTHALDEHYDE;6-Methoxy-2-Naphthaidehyde;6-methoxy-2-naphthalaldehyde;6-Methoxy-2-naphthaldehyde>
CBNumber: CB7136100
Molecular Formula: C12H10O2
Formula Weight: 186.21
MOL File: 3453-33-6.mol

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6-Methoxy-2-naphthaldehyde Property

Melting point:: 81-84 °C(lit.)
Boiling point:: 196 °C / 10mmHg
Density: 1.169±0.06 g/cm3(Predicted)
vapor pressure: 0.022Pa at 25℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly, Sonicated)
form: powder to crystal
color: White to Light yellow to Light orange
Water Solubility: 150.1mg/L at 25℃
Sensitive: Air Sensitive
BRN: 1945989
InChI: InChI=1S/C12H10O2/c1-14-12-5-4-10-6-9(8-13)2-3-11(10)7-12/h2-8H,1H3
InChIKey: VZBLASFLFFMMCM-UHFFFAOYSA-N
SMILES: C1=C2C(C=C(OC)C=C2)=CC=C1C=O
LogP: 2.97 at 25℃
CAS DataBase Reference: 3453-33-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25-37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29124990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 533084
Product name: 6-Methoxy-2-naphthaldehyde
Purity: 98%
Packaging: 5g
Price: $66.12
Updated: 2025/07/31

TCI Chemical

Product number: M1090
Product name: 6-Methoxy-2-naphthaldehyde
Purity: >97.0%(GC)
Packaging: 5g
Price: $41
Updated: 2025/07/31

TCI Chemical

Product number: M1090
Product name: 6-Methoxy-2-naphthaldehyde
Purity: >97.0%(GC)
Packaging: 25g
Price: $113
Updated: 2025/07/31

TRC

Product number: M264760
Product name: 6-Methoxy-2-naphthalenecarboxaldehyde
Packaging: 250g
Price: $745
Updated: 2021/12/16

TRC

Product number: M264760
Product name: 6-Methoxy-2-naphthalenecarboxaldehyde
Packaging: 25g
Price: $100
Updated: 2021/12/16

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6-Methoxy-2-naphthaldehyde Chemical Properties,Usage,Production

Chemical Properties

yellow to beige-yellow crystals or crystalline

Uses

6-Methoxy-2-naphthaldehyde is used as a diagnostic reagent in tumor studies involving aldehyde dehydrogenase enzymes. In addition it is used in organic synthesis reactions forming fluorescent substrates for inhibition studies relating to hypertension and vascular inflammation. It is also used as intermediate of Nabumetone.

Uses

6-Methoxy-2-naphthaldehyde may be used in the preparation of the following 4-(6-methoxy-2-naphthyl)butan-2-one related compounds:

4-(6-methoxy-2-naphthyl)but-3-en-2-one
4-(6-methoxy-2-naphthyl)-3-methylbutan-2-one
5-(6-methoxy-2-naphthyl)pentan-3-one

It may also be used in the synthesis of the following chalcone derivatives:

(2E)-1-(2-hydroxyphenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one
(2E)-1-(2-chloropyridin-4-yl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one
(2E)-3-(6-methoxy-2-naphthyl)-1-pyridin-4-ylprop-2-en-1-one
(2E)-1-(2,4-dichlorophenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 4587, 1988 DOI: 10.1021/jo00254a035

General Description

6-Methoxy-2-naphthaldehyde can be prepared by reacting 2-bromo 6-methoxy naphthalene with triethylorthoformate via Grignard reaction. Its crystals belong to the orthorhombic space group, P212121 and shows excellent NLO (non-linear optical) property.

Flammability and Explosibility

Not classified

6-Methoxy-2-naphthaldehyde Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide Tin 2-Methoxynaphthalene Tetrahydrofuran Bromine Acetic acid n-Butyllithium

Preparation Products

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6-Methoxy-2-naphthaldehyde Suppliers

Americas 1 Belgium 1 Canada 2 China 271 Europe 3 France 1 Germany 6 India 38 Japan 3 Russia 1 Slovakia 1 South Korea 2 Switzerland 2 The Netherlands 1 Ukraine 2 United Kingdom 12 United States 35 Global 382

Hubei Hongxin Ruiyu Fine Chemical Co., Ltd.

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Energy Chemical

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Capot Chemical Co., Ltd

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View Lastest Price from 6-Methoxy-2-naphthaldehyde manufacturers

Anhuyan (Hainan) Biotechnology Co., LTD

Product: 6-Methoxy-2-naphthaldehyde 3453-33-6
Price: US $0.00/G/KG
Min. Order: 1G/KG
Purity: 99%
Supply Ability: 100000
Release date: 2025-02-12

Shaanxi Dideu Medichem Co. Ltd

Product: 6-Methoxy-2-naphthaldehyde 3453-33-6
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-25

Henan Fengda Chemical Co., Ltd

Product: 6-Methoxy-2-naphthaldehyde 3453-33-6
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-16

3453-33-6, 6-Methoxy-2-naphthaldehydeRelated Search:

6-methoxy-1-tetralone 2-Bromo-6-methoxynaphthalene 2-Acetyl-6-methoxynaphthalene 6-Methoxy-2-naphthaldehyde CHROMOMYCIN A3 6-METHOXY-2-NAPHTHOIC ACID 6-ACETOXY-2-NAPHTHOIC ACID 2-ACETYL-5-BROMO-6-METHOXYNAPHTHALENE MITHRAMYCIN A 6'-Methoxy-2'-propiononaphthone 3,8-DIMETHOXY-2-NAPHTHALDEHYDE 2-METHOXY-1-NAPHTHALDEHYDE 4-METHOXY-1-NAPHTHALDEHYDE 2-Naphthaldehyde 1-(5-BROMO-6-METHOXY-2-NAPHTHYL)-1-PROPANONE 5,6,7-trimethoxy-2-naphthoic acid 2-methoxy-1-naphthaldehyde thiosemicarbazone 1,2,3,4-Tetrahydro-6-methoxy-2-naphthaldehyde

LABOTEST-BB LT01147524

ASINEX-REAG BAS 07663025

6-METHOXY-2-NAPHTHALDEHYDE

TIMTEC-BB SBB010060

6-methoxy-2-naphthalaldehyde

6-methoxynaphthalene-2-carbaldehyde

6-Methoxy-2-Naphtaldehyde

6-Methoxy-2-naphthaldehyde,99%

6-METHOXY-2-NAPHTHALDEHYDENABUMETONE

6-Methoxy-2-naphthaldehyde ,98%

6-Methoxy-2-naphthalenecarbaldehyde

2-Naphthalenecarboxaldehyde, 6-Methoxy-

6-Methoxy-2-Naphthaidehyde

6-Methoxy -2-naphthalene forMaldehyde

6-Methoxy-2-naphthaldehyde 98%

6-Methoxy-2-naphthaldehyde&gt

2-ACETYL-6-METHOXYNAPHTHALENE 3900-45-6

6-Methoxy-naphthalen-2-carbaldehyde

6-Methoxy-2-napthaldehyde

Mitotane Impurity 17

3453-33-6

CH3OC10H6CHO

Organic Building Blocks

ARYL ALDEHYDE

Carbonyl Compounds

C10 to C21

Building Blocks

Aldehydes

Building Blocks

C10-C12

Carbonyl Compounds

Chemical Synthesis

Organic Building Blocks

Aromatic Aldehydes & Derivatives (substituted)

Aldehydes

C10 to C21

Carbonyl Compounds

1

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