ChemicalBook > CAS DataBase List > 6-Methoxy-2-naphthaldehyde

6-Methoxy-2-naphthaldehyde

Product Name
6-Methoxy-2-naphthaldehyde
CAS No.
3453-33-6
Chemical Name
6-Methoxy-2-naphthaldehyde
Synonyms
TIMTEC-BB SBB010060;Mitotane Impurity 17;LABOTEST-BB LT01147524;ASINEX-REAG BAS 07663025;6-Methoxy-2-Naphtaldehyde;6-Methoxy-2-napthaldehyde;6-METHOXY-2-NAPHTHALDEHYDE;6-Methoxy-2-Naphthaidehyde;6-methoxy-2-naphthalaldehyde;6-Methoxy-2-naphthaldehyde>
CBNumber
CB7136100
Molecular Formula
C12H10O2
Formula Weight
186.21
MOL File
3453-33-6.mol
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6-Methoxy-2-naphthaldehyde Property

Melting point:
81-84 °C(lit.)
Boiling point:
196 °C / 10mmHg
Density 
1.169±0.06 g/cm3(Predicted)
vapor pressure 
0.022Pa at 25℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly, Sonicated)
form 
powder to crystal
color 
White to Light yellow to Light orange
Water Solubility 
150.1mg/L at 25℃
Sensitive 
Air Sensitive
BRN 
1945989
LogP
2.97 at 25℃
CAS DataBase Reference
3453-33-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29124990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
533084
Product name
6-Methoxy-2-naphthaldehyde
Purity
98%
Packaging
5g
Price
$67.5
Updated
2024/03/01
TCI Chemical
Product number
M1090
Product name
6-Methoxy-2-naphthaldehyde
Purity
>97.0%(GC)
Packaging
5g
Price
$41
Updated
2024/03/01
TCI Chemical
Product number
M1090
Product name
6-Methoxy-2-naphthaldehyde
Purity
>97.0%(GC)
Packaging
25g
Price
$113
Updated
2024/03/01
Alfa Aesar
Product number
B23943
Product name
6-Methoxy-2-naphthaldehyde, 99%
Packaging
5g
Price
$40.65
Updated
2024/03/01
Alfa Aesar
Product number
B23943
Product name
6-Methoxy-2-naphthaldehyde, 99%
Packaging
25g
Price
$133.65
Updated
2024/03/01
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6-Methoxy-2-naphthaldehyde Chemical Properties,Usage,Production

Chemical Properties

yellow to beige-yellow crystals or crystalline

Uses

6-Methoxy-2-naphthaldehyde is used as a diagnostic reagent in tumor studies involving aldehyde dehydrogenase enzymes. In addition it is used in organic synthesis reactions forming fluorescent substrates for inhibition studies relating to hypertension and vascular inflammation. It is also used as intermediate of Nabumetone.

Uses

6-Methoxy-2-naphthaldehyde may be used in the preparation of the following 4-(6-methoxy-2-naphthyl)butan-2-one related compounds:

  • 4-(6-methoxy-2-naphthyl)but-3-en-2-one
  • 4-(6-methoxy-2-naphthyl)-3-methylbutan-2-one
  • 5-(6-methoxy-2-naphthyl)pentan-3-one

It may also be used in the synthesis of the following chalcone derivatives:
  • (2E)-1-(2-hydroxyphenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one
  • (2E)-1-(2-chloropyridin-4-yl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one
  • (2E)-3-(6-methoxy-2-naphthyl)-1-pyridin-4-ylprop-2-en-1-one
  • (2E)-1-(2,4-dichlorophenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 4587, 1988 DOI: 10.1021/jo00254a035

General Description

6-Methoxy-2-naphthaldehyde can be prepared by reacting 2-bromo 6-methoxy naphthalene with triethylorthoformate via Grignard reaction. Its crystals belong to the orthorhombic space group, P212121 and shows excellent NLO (non-linear optical) property.

Flammability and Explosibility

Not classified

6-Methoxy-2-naphthaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Methoxy-2-naphthaldehyde Suppliers

TCI Chemicals (India) Pvt. Ltd.
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View Lastest Price from 6-Methoxy-2-naphthaldehyde manufacturers

Hubei Yiling biotechnology Co Ltd
Product
6-Methoxy-2-naphthaldehyde 3453-33-6
Price
US $0.00/G/KG
Min. Order
1G/KG
Purity
99%
Supply Ability
100000
Release date
2025-02-12
Shaanxi Dideu Medichem Co. Ltd
Product
6-Methoxy-2-naphthaldehyde 3453-33-6
Price
US $1.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20T
Release date
2024-07-25
Henan Fengda Chemical Co., Ltd
Product
6-Methoxy-2-naphthaldehyde 3453-33-6
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-16

3453-33-6, 6-Methoxy-2-naphthaldehydeRelated Search:


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  • Mitotane Impurity 17
  • 3453-33-6
  • CH3OC10H6CHO
  • Organic Building Blocks
  • ARYL ALDEHYDE
  • Carbonyl Compounds
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