4-Methoxy-1-naphthaldehyde

Product Name: 4-Methoxy-1-naphthaldehyde
CAS No.: 15971-29-6
Chemical Name: 4-Methoxy-1-naphthaldehyde
Synonyms: AKOS B022255;TIMTEC-BB SBB000256;4-Methoxy-1-Naphtol;4-METHOXY-1-NAPHTHALDEHYDE;4-Methoxy-1-naphthylaldehyde;4-methoxy-1-naphthalaldehyde;1-Naphthaldehyde, 4-methoxy-;4-Methoxy-1-naphthaldehyde>4-Methoxy-1-naphthaldehyde,99%;4-monomethoxy-1-naphthaldehyde
CBNumber: CB7207516
Molecular Formula: C12H10O2
Formula Weight: 186.21
MOL File: 15971-29-6.mol

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4-Methoxy-1-naphthaldehyde Property

Melting point:: 35-36 °C(lit.)
Boiling point:: 212 °C40 mm Hg(lit.)
Density: 1.1879
refractive index: 1.6640
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Low Melting Solid
color: Slightly beige to pink-brown
Sensitive: Air Sensitive
BRN: 2046436
CAS DataBase Reference: 15971-29-6(CAS DataBase Reference)
NIST Chemistry Reference: 1-Naphthalenecarboxaldehyde, 4-methoxy-(15971-29-6)

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Safety

Risk Statements: 36/37/38
Safety Statements: 24/25
WGK Germany: 3
HS Code: 29124990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 103241
Product name: 4-Methoxy-1-naphthaldehyde
Purity: 99%
Packaging: 10g
Price: $211
Updated: 2025/07/31

TCI Chemical

Product number: M1049
Product name: 4-Methoxy-1-naphthaldehyde
Purity: >97.0%(GC)
Packaging: 5g
Price: $128
Updated: 2025/07/31

TRC

Product number: M331398
Product name: 4-Methoxy-1-naphthaldehyde
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M331398
Product name: 4-Methoxy-1-naphthaldehyde
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 081748
Product name: 4-Methoxy-1-naphthaldehyde
Purity: 97%
Packaging: 1g
Price: $47
Updated: 2021/12/16

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4-Methoxy-1-naphthaldehyde Chemical Properties,Usage,Production

Chemical Properties

slightly beige to pink-brown low melting solid

Uses

4-Methoxy-1-naphthaldehyde was used in fluorometric enzymatic assay for determination of activity of class I and II alcohol dehydrogenase isoenzymes in human pancreas and in human liver homogenates.

Biochem/physiol Actions

4-Methoxy-1-naphthaldehyde is fluorogenic substrate for human alcohol dehydrogenase (ADH).

Synthesis

7770-45-8

74-88-4

15971-29-6

General method: A mixture of 4-hydroxy-1-naphthaldehyde (1 eq.), potassium carbonate (K2CO3, 1.5 eq.) and iodomethane (1.5 eq.) in acetone (12 mL/mmol) was stirred under reflux conditions for 4 to 24 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) until complete disappearance of the raw material. Upon completion of the reaction, the solvent was removed by evaporation under reduced pressure. The residue was purified by silica gel column chromatography with an eluent ratio of cyclohexane/ethyl acetate (90:10 to 70:30).

References

[1] Physical Chemistry Chemical Physics, 2015, vol. 17, # 15, p. 10238 - 10249
[2] European Journal of Medicinal Chemistry, 2016, vol. 123, p. 161 - 170
[3] Justus Liebigs Annalen der Chemie, 1907, vol. 357, p. 373
[4] Journal of the American Chemical Society, 1982, vol. 104, # 16, p. 4469 - 4477
[5] Journal of Medicinal Chemistry, 2012, vol. 55, # 20, p. 8969 - 8973

4-Methoxy-1-naphthaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Methoxy-1-naphthaldehyde Suppliers

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China Langchem Inc.

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View Lastest Price from 4-Methoxy-1-naphthaldehyde manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: 4-Methoxy-1-naphthaldehyde 15971-29-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 2000
Release date: 2025-04-18

Career Henan Chemical Co

Product: 4-Methoxy-1-naphthaldehyde 15971-29-6
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: JD 828
Release date: 2019-09-02

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15971-29-6

Building Blocks

Aldehydes

C10 to C21

Carbonyl Compounds

ALDEHYDE

Organic Building Blocks

Aldehydes

C10 to C21

Carbonyl Compounds