ChemicalBook > CAS DataBase List > 1,4-Cyclohexanedione

1,4-Cyclohexanedione

Product Name
1,4-Cyclohexanedione
CAS No.
637-88-7
Chemical Name
1,4-Cyclohexanedione
Synonyms
CHD;Cyclohexane-1,4-dione;CYCLOHEXANEDIONE;1,4-Cyclohexadione;Tetrahydroquinone;1,4-CYCHEXANEDIONE;1,4-CYCLOHEXANDIONE;1,4-cyclohexanedion;Cyclohexan-1,4-dione;1,4-Dioxocyclohexane
CBNumber
CB7138205
Molecular Formula
C6H8O2
Formula Weight
112.13
MOL File
637-88-7.mol
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1,4-Cyclohexanedione Property

Melting point:
77-78.5 °C (lit.)
Boiling point:
112 °C (19.5026 mmHg)
Density 
1.0861
refractive index 
1.4570 (estimate)
Flash point:
132 °C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in methanol and ethanol.
form 
Crystalline Powder or Flakes
color 
Light yellow to yellow or beige
BRN 
774152
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
LogP
-0.910 (est)
CAS DataBase Reference
637-88-7(CAS DataBase Reference)
NIST Chemistry Reference
1,4-Cyclohexanedione(637-88-7)
EPA Substance Registry System
1,4-Cyclohexanedione (637-88-7)
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Safety

Hazard Codes 
Xi
Safety Statements 
22-24/25
WGK Germany 
3
F 
8
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29142900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
125423
Product name
1,4-Cyclohexanedione
Purity
98%
Packaging
10g
Price
$60.5
Updated
2024/03/01
Sigma-Aldrich
Product number
125423
Product name
1,4-Cyclohexanedione
Purity
98%
Packaging
50g
Price
$111
Updated
2024/03/01
TCI Chemical
Product number
C0730
Product name
1,4-Cyclohexanedione
Purity
>98.0%(GC)
Packaging
25g
Price
$54
Updated
2024/03/01
TCI Chemical
Product number
C0730
Product name
1,4-Cyclohexanedione
Purity
>98.0%(GC)
Packaging
500g
Price
$527
Updated
2024/03/01
Alfa Aesar
Product number
A11100
Product name
1,4-Cyclohexanedione, 98%
Packaging
25g
Price
$58
Updated
2024/03/01
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1,4-Cyclohexanedione Chemical Properties,Usage,Production

Chemical Properties

tan or yellow crystalline powder

Uses

1,4-Cyclohexanedione is used in the preparation of 1,4 benzoquinone and bromoorganics. It is also used to study the influence of visible light on the bromate-1,4-cyclohexanedione-ferroin oscillating reaction. It plays a vital role in pharmaceuticals, plant growth regulator and as a conducting material.

Definition

ChEBI: 1,4-Cyclohexanedione is a cyclohexanedione with oxo substituents at positions 1 and 4.

Preparation

Synthesis of 1,4-cyclohexanedione: put diethyl succinylsuccinate into a flask, add a mixture of concentrated sulfuric acid, water and ethanol, reflux in oil solution for 5 days, cool, and neutralize to pH with ammonia water = 8; then extract 4 times with chloroform, and recover the chloroform to obtain the crude product; then the crude product is subjected to vacuum distillation, and the distillate is poured into cold petroleum ether, filtered, and air-dried to obtain 1,4-cyclohexanedi Ketone Products.

Synthesis Reference(s)

Synthesis, p. 165, 1981 DOI: 10.1055/s-1981-29377

General Description

1,4-Cyclohexanedione(CHD) undergoes uncatalyzed oscillatory reactions during oxidation by acidic bromate in nitric acid and sulphuric acid solution. It reacts with acidic bromate to form 1,4-dihydroxybenzene which on further oxidation and bromination yields 1,4-benzoquinone and bromoorganics.

Pharmacology

The cyclohexanedione (CHD) herbicides inhibit fatty acid synthesis in plants by interfering with the activity of the enzyme Acetyl-Coenzyme A Carboxylase (ACCase). ACCase-inhibiting herbicides provide excellent control of grass weeds in dicotyledonous and some grass crops. A less-sensitive ACCase mediates the intrinsic resistance of dicotyledonous plants to the AOPP and CHD herbicides (34,35). Although grasses are target species of this group of herbicides, not all are equally affected, and sensitivity differences can occur between varieties or even within a genus.

1,4-Cyclohexanedione Preparation Products And Raw materials

Raw materials

dilute sulphuric acid Diethyl succinosuccinate Diethyl succinate

Preparation Products

HOMOGENTISIC ACID GAMMA-LACTONE trans-1,4-Diaminocyclohexane trans-4-Aminocyclohexanol Pentacene
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1,4-Cyclohexanedione Suppliers

Americas 1 Belgium 1 China 334 Europe 3 Germany 8 India 19 Japan 4 Slovakia 1 South Korea 2 Switzerland 1 United Kingdom 8 United States 33 Global 415
Pure Chemistry Scientific Inc.
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View Lastest Price from 1,4-Cyclohexanedione manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
1,4-Cyclohexanedione 637-88-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 MT
Release date
2024-11-08
Hebei Mujin Biotechnology Co.,Ltd
Product
1,4-Cyclohexanedione 637-88-7
Price
US $50.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20tons
Release date
2023-07-31
Hebei Yanxi Chemical Co., Ltd.
Product
1,4-Cyclohexanedione 637-88-7
Price
US $40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-10-16

637-88-7, 1,4-Cyclohexanedione Related Search:

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