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palbinone

Product Name: palbinone
CAS No.: 139954-00-0
Chemical Name: palbinone
Synonyms: palbinone;18-Norandrosta-11,13(17)-diene-15,16-dione, 3,17-dihydroxy-4,4,8,14-tetramethyl-, (3β,5α)-;(3beta,5alpha)-3,17-Dihydroxy-4,4,8,14-tetramethyl-18-norandrosta-11,13(17)-diene-15,16-dione
CBNumber: CB71388056
Molecular Formula: C22H30O4
Formula Weight: 358.4712
MOL File: 139954-00-0.mol

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palbinone Property

Boiling point:: 508.5±50.0 °C(Predicted)
Density: 1.22±0.1 g/cm3(Predicted)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: powder
pka: 6.72±0.70(Predicted)
color: Orange

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN96019
Product name: Palbinone
Packaging: 5mg
Price: $513
Updated: 2021/12/16

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palbinone Chemical Properties,Usage,Production

Uses

Palbinone is a terpenoid isolated from the roots of Paeonia albiflora Pallas, potently inhibits 3α-hydroxysteroid dehydrogenase (3α-HSD), with an IC50 of 46 nM. Anti-inflammatory activity[1].

Definition

ChEBI: A natural product found in Paeonia rockii subspecies rockii.

target

HO-1 | Nrf2 | PI3K | Akt | ERK | NADPH-oxidase

References

[1] Kadota S, et al. Palbinone, a novel terpenoid from Paeonia albiflora; potent inhibitory activity on 3 alpha-hydroxysteroid dehydrogenase. Chem Pharm Bull (Tokyo). 1993 Mar;41(3):487-90. DOI:10.1248/cpb.41.487

palbinone Preparation Products And Raw materials

Raw materials

Preparation Products

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(3beta,5alpha)-3,17-Dihydroxy-4,4,8,14-tetramethyl-18-norandrosta-11,13(17)-diene-15,16-dione

18-Norandrosta-11,13(17)-diene-15,16-dione, 3,17-dihydroxy-4,4,8,14-tetramethyl-, (3β,5α)-

139954-00-0