7-AMINOACTINOMYCIN D
- Product Name
- 7-AMINOACTINOMYCIN D
- CAS No.
- 7240-37-1
- Chemical Name
- 7-AMINOACTINOMYCIN D
- Synonyms
- 7-AAD;7-ADD;7-AMINO-AMD;7-AAD/CH85402;7-ACTINOMYCIN C;7-AMINOACTINOMYCIN;7-AMINODACTINOMYCIN;7-AMINOACTINOMYCIN D;7-AMINOACTINOMYCIN C1;ACTINOMYCIN D, 7-AMINO
- CBNumber
- CB7145520
- Molecular Formula
- C62H87N13O16
- Formula Weight
- 1270.43
- MOL File
- 7240-37-1.mol
7-AMINOACTINOMYCIN D Property
- Melting point:
- 252～253℃
- Boiling point:
- 1400.8±65.0 °C(Predicted)
- Density
- 1.44
- Flash point:
- 801℃
- storage temp.
- -20°C
- solubility
- chloroform: 1 mg/mL, clear, red
- form
- powder
- pka
- 8.90±0.70(Predicted)
- color
- red to dark purple
- BRN
- 5915844
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions should be made fresh daily.
Safety
- Hazard Codes
- T+,T
- Risk Statements
- 26/27/28-36/37/38
- Safety Statements
- 26-28-36/37-45
- RIDADR
- UN 3462 6.1/PG 2
- WGK Germany
- 3
- RTECS
- AU1579000
- F
- 8-10-21
- HazardClass
- 6.1(a)
- PackingGroup
- II
- HS Code
- 29419090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A9400
- Product name
- 7-Aminoactinomycin D
- Purity
- ~97% (HPLC), powder
- Packaging
- 1mg
- Price
- $118.8
- Updated
- 2024/03/01
- Product number
- 129935
- Product name
- Actinomycin D, 7-Amino-
- Packaging
- 1mg
- Price
- $173.9
- Updated
- 2021/12/16
- Product number
- 11397
- Product name
- 7-Aminoactinomycin D
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $110
- Updated
- 2024/03/01
- Product number
- 11397
- Product name
- 7-Aminoactinomycin D
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $433
- Updated
- 2024/03/01
- Product number
- SML1633
- Product name
- 7-Aminoactinomycin D
- Purity
- 1 mg/mL
- Packaging
- 1ml
- Price
- $340
- Updated
- 2024/03/01
7-AMINOACTINOMYCIN D Chemical Properties,Usage,Production
Description
7-Aminoactinomycin D (7-AAD) is a fluorescent DNA dye that is commonly used for the detection or exclusion of non-viable cells in flow cytometric analysis, as it is generally excluded by live cells. It displays excitation spectra of 488, 546, and 578 nm and an emission spectrum of 650 nm. As 7-AAD is detected in the far red range of the spectrum, it exhibits minimal spectral overlap with commonly used probes, therefore it can be used in conjunction with probes such as FITC. 7-AAD has been used to evaluate apoptosis and cell-mediated cytotoxicity and to stain DNA in cells that have been fixed and permeabilized by a variety of methods.
Chemical Properties
Purple powder
Uses
Fluorescent DNA stain. A featured product for Apoptosis research.
Uses
7-Aminoactinomycin D is a fluorescent DNA dye for apoptosis and flow cytomtery studies.
Definition
ChEBI: 7-aminoactinomycin D is a chromopeptide. It has a role as a fluorochrome.
General Description
Free form:
Excitation: 503 nm (0.01 M phosphate buffer, pH 7.0 containing 0.1 mM EDTA); 550 nm
Emission: 675 nm (0.01 M phosphate buffer, pH 7.0 containing 0.1 mM EDTA); 672 nm
DNA Complex:
Excitation: 543 nm; 555 nm
Emission: 655 nm; 665 nm
Biochem/physiol Actions
Primary Targetleukemias and sarcomas
storage
Store at -20°C
References
1) Telieps?et al.?(2013)?Cellular-FLIP, Raji isoform (c-FLIP R) modulates cell death induction upon T-cell activation and infection, Eur. J. Immunol. 43 1499 2) Schmid?et al.?(2007)?Live-cell assay for detection of apoptosis by dual-laser flow cytometry using Hoechst 33342 and 7-amino-actinomycin D, Nat. Protoc.?2?187 3) Toba?et al.?(2000) Cell kinetic study of normal human bone marrow hematopoiesis and acute leukemia using 7AAD/PY, Eur.J.Haematol. 64 10 4) Lecoeur?et al.?(1997)?Strategies for phenotyping apoptotic peripheral human lymphocytes comparing ISNT, annexin-V and 7-AAD cytofluorometric staining methods, J. Immunol. Methods?209?111 5) Su?et al.?(1996)?Hematopoietic cell protein-tyrosine phosphatase-deficient motheaten mice exhibit T cell apoptosis defect, J. Immunol.?156?4198
7-AMINOACTINOMYCIN D Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-AMINOACTINOMYCIN D manufacturers
- Product
- 7-AMinoactinoMycin D 7240-37-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2020-05-09
- Product
- 7-AMINOACTINOMYCIN D 7240-37-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-06-24
- Product
- 7-AMINOACTINOMYCIN D 7240-37-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2019-12-30