3-Methoxy-2-methylaniline
- Product Name
- 3-Methoxy-2-methylaniline
- CAS No.
- 19500-02-8
- Chemical Name
- 3-Methoxy-2-methylaniline
- Synonyms
- 3-Methoxy-2-nitroaniline;3-Metho;3-methoxy-2-methylbenzenamine;2-Nitro-m-anisidine;2-Methyl-M-anisidine;3-METHOXY-O-TOLUIDINE;3-Methoxy-2-methylanili;2-METHYL-3-AMINO ANISOLE;3-AMINO-2-METHYL-ANISOLE;2-AMino-6-Methoxytoluene
- CBNumber
- CB4278801
- Molecular Formula
- C8H11NO
- Formula Weight
- 137.18
- MOL File
- 19500-02-8.mol
3-Methoxy-2-methylaniline Property
- Melting point:
- 27-28°C
- Boiling point:
- 243.4±20.0 °C(Predicted)
- Density
- 1.08
- refractive index
- 1.5730-1.5770
- Flash point:
- >110℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- 4.03±0.10(Predicted)
- color
- Brown to Dark Brown
- InChI
- InChI=1S/C8H11NO/c1-6-7(9)4-3-5-8(6)10-2/h3-5H,9H2,1-2H3
- InChIKey
- OPXLVWLFDKRYRB-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=CC(OC)=C1C
- CAS DataBase Reference
- 19500-02-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M1493
- Product name
- 3-Methoxy-2-methylaniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $89
- Updated
- 2025/07/31
- Product number
- M1493
- Product name
- 3-Methoxy-2-methylaniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $330
- Updated
- 2025/07/31
- Product number
- M263300
- Product name
- 3-Methoxy-2-methylaniline
- Packaging
- 5G
- Price
- $95
- Updated
- 2021/12/16
- Product number
- J94864
- Product name
- 3-Methoxy-2-methylaniline
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- 072758
- Product name
- 3-Methoxy-2-methylaniline
- Purity
- 95+%
- Packaging
- 5g
- Price
- $34
- Updated
- 2021/12/16
3-Methoxy-2-methylaniline Chemical Properties,Usage,Production
Chemical Properties
Brown Oil
Uses
3-Methoxy-2-methylaniline is a aniline derivative used in the preparation of indoles and indazoles with potential neurochemical activity, as well as in the preparation of quinoline based antiviral agents.
Synthesis
4837-88-1
19500-02-8
The general procedure for the synthesis of 3-methoxy-2-methylaniline from 2-methyl-3-nitroanisole is as follows (reference Example 42): 1. 9.98 g of a suspension of 5% palladium-carbon (wet) in 100 mL of ethanol was added to a solution of 30.7 g (184 mmol) of 2-methyl-3-nitroanisole in 300 mL of ethanol. 2. The reaction mixture was stirred at room temperature and under hydrogen atmosphere for 3 hours. 3. Upon completion of the reaction, the reaction solution was filtered through diatomaceous earth. 4. The filtrate was concentrated under vacuum to give 25.5 g of 3-methoxy-2-methylaniline as a light purple oil (Yield: quantitative). Rf value: 0.38 (hexane: ethyl acetate = 2:1, v/v). Mass spectrum (EI, m/z): 137 (M+). 1H-NMR spectrum (CDCl3, δ ppm): 2.04-2.05 (m, 3H), 3.60 (brs, 2H), 3.80 (s, 3H), 6.33-6.37 (m, 2H), 6.94-7.01 (m, 1H).
References
[1] Patent: EP1679308, 2006, A1. Location in patent: Page/Page column 56
[2] Patent: US2009/12123, 2009, A1. Location in patent: Page/Page column 14-15
[3] Patent: WO2004/103996, 2004, A1. Location in patent: Page 38-39
[4] Patent: WO2006/7700, 2006, A1. Location in patent: Page/Page column 61
[5] Patent: US2006/19905, 2006, A1. Location in patent: Page/Page column 24
3-Methoxy-2-methylaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Methoxy-2-methylaniline manufacturers
- Product
- 3-Methoxy-2-methylaniline 19500-02-8
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-19
- Product
- 3-Methoxy-2-methylaniline 19500-02-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-11-06
- Product
- 3-Methoxy-2-methylaniline 19500-02-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10