ChemicalBook > CAS DataBase List > Methyl 4-fluoro-3-methylbenzoate

Methyl 4-fluoro-3-methylbenzoate

Product Name: Methyl 4-fluoro-3-methylbenzoate
CAS No.: 180636-50-4
Chemical Name: Methyl 4-fluoro-3-methylbenzoate
Synonyms: 4-fluoro-2,3-dimethylbenzoate;Methyl 4-fluoro-3-methylbenzoate;methyl 3-Methyl-4-fluorobenzoate;3-Methyl-4-fluoroMethyl benzoate;3-Methyl-4-Fluoro benzoic acidmethyl ester;Benzoic acid, 4-fluoro-3-methyl-, methyl ester;Methyl 4-fluoro-m-toluate, 2-Fluoro-5-(methoxycarbonyl)toluene
CBNumber: CB71457620
Molecular Formula: C9H9FO2
Formula Weight: 168.16
MOL File: 180636-50-4.mol

Less

Methyl 4-fluoro-3-methylbenzoate Property

Boiling point:: 219.2±20.0℃ (760 Torr)
Density: 1.137±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:: 84.1±16.7℃
storage temp.: Sealed in dry,Room Temperature
Appearance: Colorless to off-white Solid-liquid mixture

Less

Safety

Hazard Codes: Xi
HS Code: 2916399090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

Precautionary statements

P234Keep only in original container.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P390Absorb spillage to prevent material damage.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

TRC

Product number: M321440
Product name: Methyl4-Fluoro-3-methylbenzoate
Packaging: 100mg
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2623-3-X4
Product name: Methyl 4-fluoro-3-methylbenzoate
Packaging: 1g
Price: $18
Updated: 2021/12/16

Matrix Scientific

Product number: 075269
Product name: Methyl 4-fluoro-3-methylbenzoate
Purity: 95+%
Packaging: 1g
Price: $70
Updated: 2021/12/16

Matrix Scientific

Product number: 075269
Product name: Methyl 4-fluoro-3-methylbenzoate
Purity: 95+%
Packaging: 5g
Price: $200
Updated: 2021/12/16

AK Scientific

Product number: W3922
Product name: Methyl4-Fluoro-3-methylbenzoate
Packaging: 25g
Price: $201
Updated: 2021/12/16

Less

Methyl 4-fluoro-3-methylbenzoate Chemical Properties,Usage,Production

Synthesis

148547-19-7

180636-50-4

General procedure for the synthesis of methyl 4-fluoro-3-methylbenzoate from methyl 4-bromo-3-methylbenzoate: methyl 4-bromo-3-methylbenzoate (27.5 mg, 0.12 mmol), BrettPhos (6.4 mg, 0.012 mmol, 10 mol%), (COD)Pd(CH2TMS)2 (2.3 mg. 0.006 mmol, 5 mol%), AgF (22.8 mg, 0.18 mmol, 1.5 eq.), and toluene (2 mL) were added sequentially to an oven-dried, resealable screw-cap test tube equipped with a stir bar. After sealing the test tubes, they were removed from the glove box, wrapped in aluminum foil, and placed in a preheated 130°C oil bath with sufficient stirring for 18 hours of reaction. Upon completion of the reaction, the test tubes were removed from the oil bath and cooled to room temperature. P-fluorotoluene (6.5 μL, 0.06 mmol, 0.5 eq.) and dodecane (27.3 μL, 0.12 mmol, 1 eq.) were added as internal standards. The reaction mixture was filtered through a glass filter and Celite plug to remove solid impurities. Subsequently, the clarified yellow solution was analyzed by 19F NMR (282 MHz) to determine the yield, and the conversion and reduction products were analyzed by GC. Yield was determined by comparing the 19F NMR integrals of p-fluorotoluene (-118 ppm) and methyl 4-fluoro-3-methylbenzoate (-106 ppm, 0.100 mmol, 83% yield).GC/MS analysis confirmed that the only compound in solution was methyl 4-fluoro-3-methylbenzoate.

References

[1] Patent: US2011/15401, 2011, A1. Location in patent: Page/Page column 17

Methyl 4-fluoro-3-methylbenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Methyl 4-fluoro-3-methylbenzoate Suppliers

China 73 India 1 Switzerland 1 United Kingdom 2 United States 9 Global 86

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2806
Advantage: 65

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 021-31038972,31038973 17321035817
Fax: +86-21-51385350
Email: sales@harvest-chem.com
Country: China
ProdList: 2816
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 4000
Advantage: 55

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4720
Advantage: 55

Nanjing Credit Trading Co.,Ltd

Tel: 025-52164950
Fax: 025-86800069
Email: Googlexu_0114@sina.com
Country: China
ProdList: 644
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai ACT chemical Limited

Tel: 021-59904146 18001826933
Fax: +86-21-59904146
Email: sales@actchemical.com
Country: China
ProdList: 476
Advantage: 56

Nanjing Duolong Bio-tech Co.,Ltd.

Tel: 18905173768
Fax: 025-83263139
Email: 52513593@qq.com
Country: China
ProdList: 2331
Advantage: 50

Shanghai Jovan Biochemical Technology Co. Ltd.

Tel: +86-021-61654350
Fax: +86-021-61654350
Email: 1245958370@qq.com
Country: China
ProdList: 2982
Advantage: 50

Nanjing ERan Biological Pharmaceutical Co., Ltd.

Tel: 13770809694
Fax: +86 25 56203983
Email: googlexu_0114@sina.com
Country: China
ProdList: 990
Advantage: 58

Changzhou Anxuan Chemical, Co., Ltd.

Tel: 13912302692 13912302692;
Fax: 0519-88064678
Email: sales@anxuanchem.com
Country: China
ProdList: 4828
Advantage: 58

NovoChemy Ltd.

Tel: 86-(0)21-31261262 373522135
Fax: 86-(0)21-33250524
Email: sales@novochemy.com
Country: China
ProdList: 6498
Advantage: 58

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Wuhan Chemwish Technology Co.， Ltd

Tel: 027-67849912
Fax: 027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 9148
Advantage: 60

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

NanJing Xienuo bio Co.,Ltd.

Tel: 025-84112752 13805181430
Fax: +86-25-84846489
Email: 154301870@qq.com
Country: China
ProdList: 1000
Advantage: 55

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai CR Corporation Limited

Tel: 13062833949; 4006653949 4006653949
Fax: QQ: 2136646215
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 9757
Advantage: 58

Dalian lichuang Chemical Co., Ltd

Tel: 0411-0411-00000000 13644282108
Fax: -
Email: 3500508746@qq.com
Country: China
ProdList: 2896
Advantage: 55

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Jinan Liheng Biotechnology Co., Ltd.

Tel: 0531-18763987518 18763987518
Email: levi@lihengpharm.com
Country: China
ProdList: 1797
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

Shanghai FWD Chemicals Limited

Tel: 021-54450827 021-54450828
Email: sales@fwdchem.com
Country: China
ProdList: 997
Advantage: 58

Xinyi Kangda Biological Technology Co., Ltd.

Tel: 13013943931 15152133928
Email: xinyikangda@163.com
Country: China
ProdList: 610
Advantage: 58

Xinyi Kaiwu Chemical Technology Co., Ltd.

Tel: 0516-0516-88997009 18651776937
Email: 4164357@qq.com
Country: China
ProdList: 3204
Advantage: 58

Allfluoro pharmaceutical co. ltd.

Tel: +86-400-0216110 +86-15958047586
Fax: 0086-21-33275002
Email: sales@allfluoro.com
Country: China
ProdList: 11385
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: sales@accelachem.com
Country: China
ProdList: 10467
Advantage: 58

Wuhan Chemwish Technology Co., Ltd

Tel: 027-67849912
Email: sales@chemwish.com
Country: CHINA
ProdList: 10821
Advantage: 58

Xinyi Huaju Pharmaceutical Technology Co., Ltd.

Tel: 13761372795
Email: huajupharm@163.com
Country: China
ProdList: 806
Advantage: 58

Yuzhou Enthalpy Carbon Pharmaceutical Technology Co. LTD

Tel: 19963477321; 19963477321
Fax: QQ:2041275825
Email: 2041275825@qq.com
Country: China
ProdList: 1447
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Shandong Mingde Biotechnology Co., Ltd

Tel: 15553348166
Email: m15553348166@163.com
Country: China
ProdList: 9967
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Heze Bona Medical Technology Co., LTD

Tel: 18615487702
Email: 614989876@qq.com
Country: China
ProdList: 3000
Advantage: 58

180636-50-4, Methyl 4-fluoro-3-methylbenzoateRelated Search:

METHYL 4-FLUORO-2-HYDROXYBENZOATE Methyl 4-fluoro-3-nitrobenzoate Benzoic acid, 4-fluoro-3-methoxy-5-nitro-, methyl ester Methyl 4-fluoro-2-methyl-5-nitrobenzoate 98% Methyl 4-fluoro-5-Methoxy-2-nitrobenzoate Methyl4-fluoro-3-iodobenzoate Benzoic acid，4-fluoro-2,6-dimethyl-， methyl ester Methyl 4-fluoro-3-(trifluoroMethyl)benzoate 4-FLUORO-2-METHOXYBENZOIC ACID METHYL ESTER METHYL 4-FLUORO-3-HYDROXYBENZOATE methyl 4-fluoro-3-methoxyphenylacetate RARECHEM AL BF 0506 methyl 4-fluoro-2-methyl-3-nitrobenzoate Methyl 3-cyano-4-fluorobenzoate Methyl 4-fluoro-3-methylbenzoate 4-FLUORO-3-METHYLBENZOIC ACID Methyl 3-methylbenzoate 2,4-DIFLUORO-5-METHYLBENZOIC ACID METHYL ESTER

Methyl 4-fluoro-3-methylbenzoate

3-Methyl-4-Fluoro benzoic acidmethyl ester

3-Methyl-4-fluoroMethyl benzoate

Methyl 4-fluoro-m-toluate, 2-Fluoro-5-(methoxycarbonyl)toluene

4-fluoro-2,3-dimethylbenzoate

Benzoic acid, 4-fluoro-3-methyl-, methyl ester

methyl 3-Methyl-4-fluorobenzoate

180636-50-4

blocks

Carboxes

FluoroCompounds