ChemicalBook > CAS DataBase List > 3-((2,2,2- trifluoroethyl)thio)aniline

3-((2,2,2- trifluoroethyl)thio)aniline

Product Name
3-((2,2,2- trifluoroethyl)thio)aniline
CAS No.
1445684-99-0
Chemical Name
3-((2,2,2- trifluoroethyl)thio)aniline
Synonyms
NA12878;CarolGold;PBA-PEG-AC;WKPep Erasin;Palm-Glu-OtBu;Fmoc-D-Ala-Ala-OH;CarolGold (Lutein);Magnolol & Honokiol;BOC-(D)-HIS(TRT)-AIB;Octa(OtBu)-D-Glu-OtBu
CBNumber
CB71459710
Molecular Formula
C8H8F3NS
Formula Weight
207.22
MOL File
1445684-99-0.mol
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3-((2,2,2- trifluoroethyl)thio)aniline Property

InChI
InChI=1S/C8H8F3NS/c9-8(10,11)5-13-7-3-1-2-6(12)4-7/h1-4H,5,12H2
InChIKey
KMYQCBMXXMOPSD-UHFFFAOYSA-N
SMILES
C1(N)=CC=CC(SCC(F)(F)F)=C1
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

chempep
Product number
181931
Product name
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
Packaging
1g
Price
$300
Updated
2021/12/16
Iris Biotech GmbH
Product number
FAA7750
Product name
Fmoc-D-Lys(Palm-D-Glu-OtBu)-OH
Packaging
1g
Price
$607.5
Updated
2021/12/16
chempep
Product number
181931
Product name
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
Packaging
5g
Price
$900
Updated
2021/12/16
chempep
Product number
181931
Product name
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
Packaging
25g
Price
$2000
Updated
2021/12/16
Iris Biotech GmbH
Product number
FAA7750
Product name
Fmoc-D-Lys(Palm-D-Glu-OtBu)-OH
Packaging
5G
Price
$2160
Updated
2021/12/16
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3-((2,2,2- trifluoroethyl)thio)aniline Chemical Properties,Usage,Production

Uses

3-((2,2,2-trifluoroethyl)thio)aniline can be used as an intermediate in pharmaceutical research.

Synthesis

To a solution of 3-aminobenzenethiol (4.43 g, 35.4 mmol) in THF (225 mL) was added sodium hydride (1.77 g, 44.3 mmol) at 0 °C and stirred for 30 min. Then, 2,2,2-trifluoroethyl 4- methylbenzenesulfonate (9.0 g, 35.4 mmol) was added and the reaction mixture was stirred for 18 h. The reaction mixture was quenched with water (20 mL) and extracted with EtOAc (2x50 mL). The combined organic extracts were washed with water, dried over Na2SO4, fdtered, and concentrated under reduced pressure. The crude residue was purified by flash chromatography through a Redi-Sep pre-packed silica gel column, eluting with a gradient of 5 % to 10 % EtOAc in hexanes, to give 3-((2,2,2- trifluoroethyl)thio)aniline (5 g, 68 % yield) as a pale brown oil.

3-((2,2,2- trifluoroethyl)thio)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

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3-((2,2,2- trifluoroethyl)thio)aniline Suppliers

BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
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View Lastest Price from 3-((2,2,2- trifluoroethyl)thio)aniline manufacturers

Career Henan Chemical Co
Product
4-Chluoro-2-bromotoluene 1445684-99-0
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
98%
Supply Ability
1kg,2kg,100kg
Release date
2019-07-09

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