Catalpalactone

Product Name: Catalpalactone
CAS No.: 1585-68-8
Chemical Name: Catalpalactone
Synonyms: Catalpalactone;1(3H)-Isobenzofuranone,3-(5,6-dihydro-6,6-dimethyl-2-oxo-2H-pyran-3-yl)-
CBNumber: CB71469647
Molecular Formula: C15H14O4
Formula Weight: 258.27
MOL File: 1585-68-8.mol

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Catalpalactone Property

Melting point:: 110-111 °C
Boiling point:: 467.1±45.0 °C(Predicted)
Density: 1.269±0.06 g/cm3(Predicted)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
LogP: 2.050 (est)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN99670
Product name: Catalpalactone
Purity: ≥98%
Packaging: 5mg
Price: $373
Updated: 2021/12/16

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Catalpalactone Chemical Properties,Usage,Production

Uses

Catalpalactone has anti-inflammatory effect. Catalpalactone inhibits LPS-induced NO production and iNOS expression in RAW264.7 cells, and also inhibits IRF3, NF-κB, and IFN-β/STAT-1 activation. Catalpalactone also inhibits dopamine biosynthesis by reducing tyrosine hydroxylase (TH) and aromatic-l-amino acid decarboxylase (AADC) activities[1][2].

Definition

ChEBI: Catalpalactone is a member of 2-benzofurans.

target

cAMP | NO

References

[1] Kim HY, et al. Anti-Inflammatory Effects of Catalpalactone Isolated from Catalpa ovata in LPS-Induced RAW264.7 Cells. Molecules. 2019 Mar 29;24(7):1236. DOI:10.3390/molecules24071236
[2] Huang HS, et al. Effects of catalpalactone on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells. Environ Toxicol Pharmacol. 2008 Jul;26(1):86-91. DOI:10.1016/j.etap.2008.02.005

Catalpalactone Preparation Products And Raw materials

Raw materials

Preparation Products

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Catalpalactone Suppliers

China 45 United States 4 Global 49

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Catalpalactone

1(3H)-Isobenzofuranone,3-(5,6-dihydro-6,6-dimethyl-2-oxo-2H-pyran-3-yl)-

1585-68-8