ChemicalBook > CAS DataBase List > 1H-INDAZOLE-5-CARBALDEHYDE

1H-INDAZOLE-5-CARBALDEHYDE

Product Name
1H-INDAZOLE-5-CARBALDEHYDE
CAS No.
253801-04-6
Chemical Name
1H-INDAZOLE-5-CARBALDEHYDE
Synonyms
5-FORMYL INDAZOLE;5-Formyl-1H-indazole;1H-Indazol-5-carbaldehyde;1H-INDAZOLE-5-CARBALDEHYDE;1H-indazole-5-carbaldehyd...;1H-Indazole-5-carboxaldehyde;Indazole-5-carboxaldehyde 96%;Indazole-5-carboxaldehyde, 96%;1H-Indazole-5-carboxaldehyde ,95%;1H-Indazole-5-carboxaldehyde (9CI)
CBNumber
CB7147726
Molecular Formula
C8H6N2O
Formula Weight
146.15
MOL File
253801-04-6.mol
More
Less

1H-INDAZOLE-5-CARBALDEHYDE Property

Melting point:
115-119°C
Boiling point:
358.3±15.0 °C(Predicted)
Density 
1.368±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
solid
pka
12.87±0.40(Predicted)
Appearance
White to light yellow Solid
More
Less

Safety

WGK Germany 
3
HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
702285
Product name
Indazole-5-carboxaldehyde
Purity
96%
Packaging
1g
Price
$149
Updated
2025/07/31
TRC
Product number
I505265
Product name
1H-Indazole-5-carbaldehyde
Packaging
500mg
Price
$225
Updated
2021/12/16
Usbiological
Product number
412391
Product name
1H-Indazole-5-carbaldehyde
Packaging
100mg
Price
$340
Updated
2021/12/16
Matrix Scientific
Product number
070374
Product name
1H-Indazole-5-carboxaldehyde
Purity
97%
Packaging
1g
Price
$114
Updated
2021/12/16
Matrix Scientific
Product number
070374
Product name
1H-Indazole-5-carboxaldehyde
Purity
97%
Packaging
5g
Price
$273
Updated
2021/12/16
More
Less

1H-INDAZOLE-5-CARBALDEHYDE Chemical Properties,Usage,Production

Synthesis

53857-57-1

68-12-2

253801-04-6

A) Preparation of intermediate 1H-indazole-5-carboxaldehyde: 2.60 g (65.00 mmol, 60% dispersed in mineral oil) of sodium hydride was added batchwise to 150 mL of tetrahydrofuran (THF) solution containing 11.64 g (59.08 mmol) of 5-bromo-1H-indazole under argon gas protection, and the addition process lasted for 10 minutes. After the addition was completed, the reaction mixture was stirred for 15 min at room temperature. Subsequently, the reaction mixture was cooled to -70°C and 100.00 mL (130.00 mmol, 1.3 M in cyclohexane) of sec-butyllithium solution was slowly added dropwise over 30 min, keeping the reaction temperature below -60°C. After the dropwise addition was completed, stirring was continued for 2 h at -70°C. The reaction mixture was then stirred for 10 min at room temperature. Then, 20.00 mL (0.260 mol) of N,N-dimethylformamide (DMF) dissolved in 20 mL of THF was added dropwise, keeping the reaction temperature below -50°C. The reaction mixture was then slowly warmed to room temperature and stirred for 16 hr. Upon completion of the reaction, the mixture was cooled to 0°C and 180 mL of aqueous 2N hydrochloric acid was slowly added dropwise and stirring was continued for 15 min. The pH was adjusted to 9-10 with saturated aqueous sodium bicarbonate. the aqueous phase was fully extracted with ethyl acetate (EtOAc) and the organic phases were combined. The organic phase was dried with magnesium sulfate and concentrated under reduced pressure. The product was purified by column chromatography (silica gel, petroleum ether/EtOAc 1:1 v/v), ground with hexane and dried. Drying under reduced pressure at 50°C gave the target product 1H-indazole-5-carbaldehyde. Yield: 4.40 g (51% yield). Thin layer chromatography (TLC) Rf = 0.37 (silica gel, petroleum ether/EtOAc 1:1 v/v). Electrospray ionization mass spectrometry (ESI-MS): (M + H)+ = 147.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 16, p. 4482 - 4485
[2] Patent: WO2005/84672, 2005, A1. Location in patent: Page/Page column 40-41
[3] Patent: US2005/227968, 2005, A1. Location in patent: Page/Page column 15-16
[4] Patent: WO2008/154241, 2008, A1. Location in patent: Page/Page column 67

1H-INDAZOLE-5-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1H-INDAZOLE-5-CARBALDEHYDE Suppliers

China 141 Europe 1 Germany 3 India 2 United Kingdom 3 United States 26 Global 176
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.
Tel
21-57721279
Fax
QQ：14057904
Email
sales@shydchem.com.cn
Country
China
ProdList
998
Advantage
56
Shangchem Co., Ltd.
Tel
+86-21-68182121
Fax
+86-21-68182121
Country
China
ProdList
882
Advantage
52
ZEROSCHEM.CO.,LTD.
Tel
10-61256048 13810278579
Fax
+86 10 61256049
Email
sales@zeroschem.com
Country
China
ProdList
1370
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
skychemical Co.Ltd
Tel
021-20958197 20965099
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
1183
Advantage
57
SpringPharma Tech Co.,Ltd
Tel
+86-25-68710855, +86-25-68710897
Fax
025-68710856
Email
sales@springpharma.net
Country
China
ProdList
1261
Advantage
62
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Shanghai Keepontech Co.,Ltd
Tel
021-54849683 13601642561
Fax
+86-21-54375689
Email
sales@keepontech.com
Country
China
ProdList
998
Advantage
59
Shanghai Sheepchem Co., Ltd.
Tel
+86 (21) 6715-7650
Fax
+86 (21) 6715-7651
Email
sheepchem@163.com
Country
China
ProdList
994
Advantage
60
Runpharm Technology Limited
Tel
18171398856 2968382473
Fax
0086-21-50758330
Email
service@runpharm.com
Country
China
ProdList
716
Advantage
55
Shanghai Arbor Chemical Co., Ltd.
Tel
021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
896
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Nantong MYBio-pharm. Co., Ltd.
Tel
0513-85921823 18662920231
Fax
86-513-85012876
Email
sales@ntminyanmedical.com
Country
China
ProdList
4107
Advantage
58
Shanghai YuYuan Pharmaceutical Co., Ltd.
Tel
13052276172
Fax
13052276172
Email
product@yuyuanpharm.com
Country
China
ProdList
493
Advantage
55
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6874
Advantage
55
Changsha Luxing Bio-Chem Technology Co., Ltd.
Tel
0731-88827538 15873153880
Fax
0731-88827238
Email
luxingbc@126.com
Country
China
ProdList
1995
Advantage
65
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Shenzhen Gre-syn Chemical Technology Co., Ltd.
Tel
0755-0755-89366401 18617066401
Fax
-
Email
hangbingfang@163.com
Country
China
ProdList
951
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
3A SpeedChemical Inc
Tel
21-65679720
Fax
0086-21-5186 1128
Email
service@speedchemical.com
Country
China
ProdList
604
Advantage
55
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12000
Advantage
58
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Shanghai Kahn Pharmaceutical Co., Ltd.
Tel
021-34979681; 17701870669
Fax
021-34979681
Email
41513101@qq.com
Country
China
ProdList
1785
Advantage
55
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7991
Advantage
55
skychemical Co.Ltd
Tel
021-20960837,QQ1332204249
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
3341
Advantage
55
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9274
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
TaiChem Taizhou Limited
Tel
052386810091
Email
zcwy9518@yeah.net
Country
China
ProdList
3912
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Changzhou PBpharmaceutical R&D Co.,Ltd
Tel
086-0519-83990708 18915800124
Fax
0519-83990708
Email
info@pbpharm.com
Country
China
ProdList
487
Advantage
55
Taizhou Blazer Biomedical Technology Co., Ltd.
Tel
0523-86112008 13915404123
Fax
0523-86112008
Email
sales@blazerbio.com
Country
China
ProdList
274
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Huaxing Biological Technology Co., Ltd.
Tel
18621295758
Fax
-QQ:1449085402
Email
1449085402@qq.com
Country
China
ProdList
1724
Advantage
55
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7570
Advantage
55
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15083
Advantage
58
Shanghai WangFa Chemical Technology Co., Ltd.
Tel
13918479294
Fax
-
Email
xiebenfa@163.com
Country
China
ProdList
4087
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
More
Less

View Lastest Price from 1H-INDAZOLE-5-CARBALDEHYDE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
1H-indazole-5-carboxaldehyde 253801-04-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
Career Henan Chemical Co
Product
1H-INDAZOLE-5-CARBALDEHYDE 253801-04-6
Price
US $500.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2018-08-04

253801-04-6, 1H-INDAZOLE-5-CARBALDEHYDERelated Search:

5-Carboxyindazole hydrochloride 1H-INDAZOLE-4-CARBOXYLIC ACID Ethyl 3-indoleacetate 2-Methoxycarbonyl-indane, 98 % LUCIFER YELLOW VS DILITHIUM SALT 5-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER 1-METHYL-1H-INDAZOLE-3-CARBALDEHYDE 7-METHYL-1H-INDAZOLE-3-CARBALDEHYDE 5-CHLORO-1H-INDAZOLE-3-CARBALDEHYDE,5-Chloro-1H-indazole-3-carbaldehyde ,97% 1H-INDAZOLE-3-CARBALDEHYDE 5-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE, 95+%,5-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE 1-Methyl-1H-indazole-4-carbaldehyde 6-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE 5-BROMO-1H-INDAZOLE-3-CARBALDEHYDE, 95+%,5-BROMO-1H-INDAZOLE-3-CARBALDEHYDE 6-NITRO-1H-INDAZOLE-3-CARBALDEHYDE 5-METHYL-1H-INDAZOLE-3-CARBALDEHYDE 6-BROMO-1H-INDAZOLE-3-CARBALDEHYDE 2-METHYL-2H-INDAZOLE-3-CARBALDEHYDE

  • 5-FORMYL INDAZOLE
  • 1H-INDAZOLE-5-CARBALDEHYDE
  • 1H-Indazole-5-carboxaldehyde (9CI)
  • 1H-indazole-5-carbaldehyd...
  • 6-[(4-nitrophenyl)hydrazinylidene]hexane-1,2,3,4,5-pentol
  • 6-[(4-nitrophenyl)hydrazono]hexane-1,2,3,4,5-pentol
  • 1H-Indazole-5-carboxaldehyde
  • Indazole-5-carboxaldehyde 96%
  • Indazole-5-carboxaldehyde, 96%
  • 5-Formyl-1H-indazole
  • 1H-Indazole-5-carboxaldehyde ,95%
  • 1H-Indazole-5-carboxaldehyde (9CI, ACI)
  • 1H-Indazol-5-carbaldehyde
  • 253801-04-6
  • Indazoles
  • ALDEHYDE
  • Building Blocks
  • Indazole