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Disodium edetate dihydrate

Product Name
Disodium edetate dihydrate
CAS No.
6381-92-6
Chemical Name
Disodium edetate dihydrate
Synonyms
EDTA ACID;EDTA disodium salt dihydrate;Ethylenediaminetetraacetic acid disodium salt dihydrate;VERSENE;Disodium edetate CRS;EDTA disodium salt 2-hydrate;HAMPENE ACID;EDTA SOLUTION;RED PRIMARY SOLUTION;Disodium Edetate Hydrate
CBNumber
CB7153352
Molecular Formula
C10H19N2NaO9
Formula Weight
334.26
MOL File
6381-92-6.mol
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Disodium edetate dihydrate Property

Melting point:
250 °C (dec.)(lit.)
Boiling point:
>100 °C
Density 
1.01 g/mL at 25 °C
bulk density
700kg/m3
FEMA 
4520 | ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
refractive index 
n20/D 1.363
Flash point:
>100℃
storage temp. 
room temp
solubility 
3  M NaOH: 100 mg/mL
form 
crystalline
pka
pK1:1.99;pK2:2.67;pK3:6.16;pK4:10.26 (25°C)
color 
≤5 (0.5 M)(APHA)
PH
4.0-5.5 (25℃, 0.1M in H2O)
Odor
Odorless
PH Range
4 - 5 at 10 g/l at 23 °C
biological source
synthetic (organic)
Water Solubility 
soluble
λmax
λ: 260 nm Amax: 0.145
λ: 280 nm Amax: 0.025
BRN 
3900609
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
QCDUWWPHAVXXQS-UHFFFAOYSA-L
CAS DataBase Reference
6381-92-6(CAS DataBase Reference)
EPA Substance Registry System
Ethylenediaminetetraacetic acid disodium salt dihydrate (6381-92-6)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36-52/53-36/38-36/37/38-22
Safety Statements 
26-61-37/39-36/37/39-36
WGK Germany 
2
RTECS 
AH4025000
3
TSCA 
Yes
HS Code 
29224995
Toxicity
LD50 orally in Rabbit: > 2000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H332Harmful if inhaled

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D2900000
Product name
Disodium edetate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
40 mg
Price
$236
Updated
2025/07/31
Sigma-Aldrich
Product number
79884
Product name
Ethylenediaminetetraacetic acid disodium salt dihydrate
Purity
suitable for HPLC, LiChropur?, 99.0-101.0% (KT)
Packaging
10G
Price
$55.8
Updated
2025/07/31
Sigma-Aldrich
Product number
BP1224
Product name
Disodium edetate
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100 mg
Price
$225
Updated
2025/07/31
Sigma-Aldrich
Product number
79884
Product name
Ethylenediaminetetraacetic acid disodium salt dihydrate
Purity
suitable for HPLC, LiChropur?, 99.0-101.0% (KT)
Packaging
50G
Price
$72.1
Updated
2025/07/31
Sigma-Aldrich
Product number
4010-OP
Product name
OmniPur EDTA, Disodium Salt, Dihydrate - CAS 6381-92-6 - Calbiochem
Packaging
250g
Price
$99.1
Updated
2025/07/31
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Disodium edetate dihydrate Chemical Properties,Usage,Production

Chemical Properties

White or almost white, crystalline powder.

Uses

Chelating agent; sequestering agent

Uses

Ethylenediamine tetraacetic acid disodium dihydrate is used as chelating agent for metals and as pharmaceutic aid (chelating agent); as preservative in cosmetic products; anticoagulant.

Uses

Ethylenediaminetetraacetic acid disodium salt dihydrate is used as a chelator of divalent cations. It inhibits enzymes such as metalloproteases that require divalent cations for activity. It is also used in chelation therapy. It acts as a sequestering agent in shampoos, cleaners and other personal care products and serves as an anticoagulant for blood samples.

Definition

ChEBI: A hydrate that is the dihydrate form of EDTA disodium salt.

General Description

Ethylenediaminetetraacetic acid disodium salt dehydrate is designated as Molecular Biology grade and is suitable for molecular biology applications. It has been analyzed for the presence of nucleases and proteases.

reaction suitability

reagent type: chelator

Biochem/physiol Actions

Zinc-dependent metalloproteinases, as well as other proteases that are stabilized by calcium, can be effectively inhibited by chelation of divalent metal ions with EDTA. Other chelators such as EGTA, specific for calcium, and 1,10-phenanthroline, highly specific for zinc, can be used to target these two different types of proteases.

Purification Methods

Analytical reagent grade material can be used as primary standard after drying at 80o. Commercial grade material can be purified by crystallisation from water or by preparing a 10% aqueous solution at room temperature, then adding ethanol slowly until a slight permanent precipitate is formed, filtering, and adding an equal volume of ethanol. The precipitate is filtered off onto a sintered-glass funnel, is washed with acetone, followed by diethyl ether, and dried in air overnight to give the dihydrate. Drying at 80o for at least 24hours converts it to the anhydrous form. [Beilstein 4 IV 2451.]

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Disodium edetate dihydrate Suppliers

Tianjin Guangfu Technology Development Co. LTD
Tel
022-85689490 13132141716
Email
sales@guangfubiaowu.com
Country
China
ProdList
1630
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
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China
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Nanjing chemical reagent co. LTD
Tel
025-58369808 17895012682
Fax
025-85312034
Email
3236925839@qq.com
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China
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Hubei Chenghai Chemical Co., Ltd
Tel
027-59220433 18327245847
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1400838877@qq.com
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China
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ShangHai Anpel Co, Ltd.
Tel
18501792038 18502138905
Email
shanpel@anpel.com.cn
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China
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shandongxinheng
Tel
1526-9161022 15269161022
Email
15269161022@163.com
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China
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Shanghai Titan Scientific Co.,Ltd
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16621234537
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chenyj@titansci.com
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China
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10000
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Hunan Hui Bai Yi New Materials Co., Ltd
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0745-2866551 19976851779
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China
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Tianjin Jinhui Taiya Chemical Reagent Co., Ltd
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022-59582624 18622766592
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2163746375@qq.com
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China
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270
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
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jkinfo@jkchemical.com
Country
China
ProdList
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View Lastest Price from Disodium edetate dihydrate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Disodium edetate dihydrate 6381-92-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-19
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
Disodium edetate dihydrate 6381-92-6
Price
US $100.00-75.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000Ton
Release date
2024-08-12
Watson Biotechnology Co.,Ltd
Product
EDTA-2Na 6381-92-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20MT
Release date
2024-10-30

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