ChemicalBook > CAS DataBase List > Disodium edetate dihydrate

Disodium edetate dihydrate

Product Name
Disodium edetate dihydrate
CAS No.
6381-92-6
Chemical Name
Disodium edetate dihydrate
Synonyms
EDTA ACID;EDTA disodium salt dihydrate;Ethylenediaminetetraacetic acid disodium salt dihydrate;VERSENE;Disodium edetate CRS;EDTA disodium salt 2-hydrate;HAMPENE ACID;EDTA SOLUTION;RED PRIMARY SOLUTION;Disodium Edetate Hydrate
CBNumber
CB7153352
Molecular Formula
C10H19N2NaO9
Formula Weight
334.26
MOL File
6381-92-6.mol
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Disodium edetate dihydrate Property

Melting point:
250 °C (dec.)(lit.)
Boiling point:
>100 °C
Density 
1.01 g/mL at 25 °C
refractive index 
n20/D 1.363
FEMA 
4520 | ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
Flash point:
>100℃
storage temp. 
room temp
solubility 
3  M NaOH: 100 mg/mL
form 
crystalline
pka
pK1:1.99;pK2:2.67;pK3:6.16;pK4:10.26 (25°C)
color 
≤5 (0.5 M)(APHA)
PH
4.0-5.5 (25℃, 0.1M in H2O)
Odor
Odorless
PH Range
4 - 5 at 10 g/l at 23 °C
Water Solubility 
soluble
λmax
λ: 260 nm Amax: 0.145
λ: 280 nm Amax: 0.025
BRN 
3900609
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
QCDUWWPHAVXXQS-UHFFFAOYSA-L
CAS DataBase Reference
6381-92-6(CAS DataBase Reference)
EPA Substance Registry System
Ethylenediaminetetraacetic acid disodium salt dihydrate (6381-92-6)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36-52/53-36/38-36/37/38-22
Safety Statements 
26-61-37/39-36/37/39-36
WGK Germany 
2
RTECS 
AH4025000
F 
3
TSCA 
Yes
HS Code 
29224995
Toxicity
LD50 orally in Rabbit: > 2000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H332Harmful if inhaled

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
4010-OP
Product name
OmniPur EDTA, Disodium Salt, Dihydrate - CAS 6381-92-6 - Calbiochem
Packaging
250g
Price
$91.4
Updated
2024/03/01
Sigma-Aldrich
Product number
324503
Product name
EDTA, Disodium Salt, Dihydrate, Molecular Biology Grade - CAS 6381-92-6 - Calbiochem
Packaging
100g
Price
$67.2
Updated
2024/03/01
Sigma-Aldrich
Product number
27285
Product name
Ethylenediaminetetraacetic acid disodium salt dihydrate
Purity
meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%
Packaging
500g
Price
$203
Updated
2024/03/01
Sigma-Aldrich
Product number
27285
Product name
Ethylenediaminetetraacetic acid disodium salt dihydrate
Purity
meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%
Packaging
1kg
Price
$285
Updated
2024/03/01
Sigma-Aldrich
Product number
27285
Product name
Ethylenediaminetetraacetic acid disodium salt dihydrate
Purity
meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%
Packaging
6x1kg
Price
$1460
Updated
2024/03/01
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Disodium edetate dihydrate Chemical Properties,Usage,Production

Chemical Properties

White or almost white, crystalline powder.

Uses

Chelating agent; sequestering agent

Uses

Ethylenediamine tetraacetic acid disodium dihydrate is used as chelating agent for metals and as pharmaceutic aid (chelating agent); as preservative in cosmetic products; anticoagulant.

Uses

Ethylenediaminetetraacetic acid disodium salt dihydrate is used as a chelator of divalent cations. It inhibits enzymes such as metalloproteases that require divalent cations for activity. It is also used in chelation therapy. It acts as a sequestering agent in shampoos, cleaners and other personal care products and serves as an anticoagulant for blood samples.

Definition

ChEBI: A hydrate that is the dihydrate form of EDTA disodium salt.

General Description

Ethylenediaminetetraacetic acid disodium salt dehydrate is designated as Molecular Biology grade and is suitable for molecular biology applications. It has been analyzed for the presence of nucleases and proteases.

Biochem/physiol Actions

Zinc-dependent metalloproteinases, as well as other proteases that are stabilized by calcium, can be effectively inhibited by chelation of divalent metal ions with EDTA. Other chelators such as EGTA, specific for calcium, and 1,10-phenanthroline, highly specific for zinc, can be used to target these two different types of proteases.

Purification Methods

Analytical reagent grade material can be used as primary standard after drying at 80o. Commercial grade material can be purified by crystallisation from water or by preparing a 10% aqueous solution at room temperature, then adding ethanol slowly until a slight permanent precipitate is formed, filtering, and adding an equal volume of ethanol. The precipitate is filtered off onto a sintered-glass funnel, is washed with acetone, followed by diethyl ether, and dried in air overnight to give the dihydrate. Drying at 80o for at least 24hours converts it to the anhydrous form. [Beilstein 4 IV 2451.]

Disodium edetate dihydrate Preparation Products And Raw materials

Raw materials

Ethylenediamine Chloroacetic acid Ethylenediamine aqueous solution Concentrated sulfuric acid Hydrochloric acid Sodium hydroxide Ethylenediaminetetraacetic acid

Preparation Products

Deinking agent for paper Triamterene copper cleaning agent JC-832 Sodium edetate cocoamide propyl amine oxide N-(4-THIOPHEN-2-YL-PHENYL)-ACETAMIDE high effective scouring agent KR-75 Paraquat alomond gum,cedo gum Bleomycin sulfate Super effect deoil agent
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View Lastest Price from Disodium edetate dihydrate manufacturers

Shandong Juchuang Chemical Co., LTD
Product
Disodium edetate dihydrate 6381-92-6
Price
US $28.00-18.00/kg
Min. Order
500kg
Purity
99.9
Supply Ability
200tons
Release date
2024-03-11
Shanghai UCHEM Inc.
Product
EDTA 2Na 6381-92-6
Price
US $18.00-211.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100kg
Release date
2023-10-27
Hebei Dongdu Import and Export Co. LTD
Product
Disodium edetate dihydrate 6381-92-6
Price
US $1250.00/ton
Min. Order
10ton
Purity
99%
Supply Ability
5000ton
Release date
2023-12-07

6381-92-6, Disodium edetate dihydrateRelated Search:

EDTA magnesium disodium EDTA calcium disodium IDRANAL(R),IDRANAL(R) II,IDRANAL II R. G.,idranal ii Folic acid Chlorophyllin Ethylenediaminetetraacetic acid disodium salt EDTA ferric sodium salt Ethyl 2-(Chlorosulfonyl)acetate Citric acid Diethyl oxalacetate sodium salt ETHYLENEDIAMINETETRAACETIC ACID CALCIUM DISODIUM SALT HYDRATE Ethylenediaminetetraacetic acid trisodium salt solution DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Sodium edetate ETHYLENEDIAMINETETRAACETIC ACID TRIPOTASSIUM SALT DIHYDRATE Ethylenediaminetetraacetic acid dipotassium salt dihydrate Manganese disodium EDTA trihydrate Ferric ammonium EDTA Edta Disodium Salt Dihydrate Ethylenediaminetetraacetic Acid Disodium Salt Dihydrate

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