ChemicalBook > CAS DataBase List > 2′,3′-O-Isopropylideneuridine

2′,3′-O-Isopropylideneuridine

Product Name
2′,3′-O-Isopropylideneuridine
CAS No.
362-43-6
Chemical Name
2′,3′-O-Isopropylideneuridine
Synonyms
2',3'-IPU;Troparil Impurity 10;Uridine 2',3'-acetonide;2,3-ISOPROPYLIDENE URIDINE;2',3'-ISOPROPYLIDENEURIDENE;2',3'-ISOPROPYLIDENEURIDINE;2',3'-Isopropylideneuridine;2',3'-O-ISOPROPYLIDENEURIDINE;2',3'-O-lsopropylideneuridine;2',3'-O-Isopropylideneuridine
CBNumber
CB7156272
Molecular Formula
C12H16N2O6
Formula Weight
284.27
MOL File
362-43-6.mol
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2′,3′-O-Isopropylideneuridine Property

Melting point:
163-166 °C
Boiling point:
426.76°C (rough estimate)
Density 
1.2932 (rough estimate)
refractive index 
1.5460 (estimate)
storage temp. 
-20°C
solubility 
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
form 
Fine Crystalline Powder or Needles
pka
9.25±0.10(Predicted)
color 
White
biological source
synthetic (organic)
Water Solubility 
water: 50mg/mL, clear to very slightly hazy, colorless to light yellow
BRN 
32671
InChI
InChI=1S/C12H16N2O6/c1-12(2)19-8-6(5-15)18-10(9(8)20-12)14-4-3-7(16)13-11(14)17/h3-4,6,8-10,15H,5H2,1-2H3,(H,13,16,17)/t6-,8-,9-,10-/m1/s1
InChIKey
GFDUSNQQMOENLR-PEBGCTIMSA-N
SMILES
OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@@H]2OC(O[C@H]12)(C)C
CAS DataBase Reference
362-43-6(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S777145
Product name
2'',3''-ISOPROPYLIDENEURIDINE
Purity
AldrichCPR
Packaging
25MG
Price
$29.8
Updated
2024/03/01
Sigma-Aldrich
Product number
I5127
Product name
2′,3′-O-Isopropylideneuridine
Purity
≥99% (HPLC)
Packaging
5g
Price
$370
Updated
2024/03/01
Sigma-Aldrich
Product number
I5127
Product name
2′,3′-O-Isopropylideneuridine
Purity
≥99% (HPLC)
Packaging
25g
Price
$1430
Updated
2024/03/01
Alfa Aesar
Product number
L03686
Product name
2',3'-Isopropylideneuridine
Packaging
1g
Price
$45.65
Updated
2024/03/01
Alfa Aesar
Product number
L03686
Product name
2',3'-Isopropylideneuridine
Packaging
5g
Price
$156.65
Updated
2024/03/01
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2′,3′-O-Isopropylideneuridine Chemical Properties,Usage,Production

Description

2',3'-Isopropylideneuridine has been shown to inhibit binding of pestivirus inhibitors by monoclonal antibodies. 2',3'-Isopropylideneuridine was also found to inhibit the replication of human immunodeficiency virus (HIV) in tissue culture by binding to the viral RNA polymerase and inhibiting its activity, preventing viral replication.

Chemical Properties

White Needle-Like Crystals

Uses

2′,3′-O-Isopropylideneuridine is used in the chemical synthesis of N-benzoylated uridine derivatives and N3-substituted 2′,3′-O-isopropylideneuridines with central nervous system (CNS) depressant activity.

Uses

2',3'-O-Isopropylideneuridine can be used as a useful precursor for the preparation of nucleic acids.

2′,3′-O-Isopropylideneuridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2′,3′-O-Isopropylideneuridine Suppliers

Alfa Chemistry
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View Lastest Price from 2′,3′-O-Isopropylideneuridine manufacturers

Honest Joy Holdings Limited
Product
2',3'-O-Isopropylideneuridine 362-43-6
Price
US $0.00/KG
Min. Order
1KG
Purity
97.1%
Supply Ability
100 tons
Release date
2022-02-18
Career Henan Chemical Co
Product
2',3'-O-ISOPROPYLIDENEURIDINE 362-43-6
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-10

362-43-6, 2′,3′-O-IsopropylideneuridineRelated Search:


  • Uridine 2',3'-acetonide
  • Uridine, 2',3'-O-(1-methylethylidene)-
  • Uridine, 2',3'-O-isopropylidene-
  • 2',3'-ISOPROPYLIDENEURIDENE
  • 2,3-ISOPROPYLIDENE URIDINE
  • 2',3'-ISOPROPYLIDENEURIDINE
  • 2',3'-IPU
  • 2',3'-O-ISOPROPYLIDENEURIDINE
  • 2',3'-O-Isopropylidene-D-uridine
  • 2'-O,3'-O-Isopropylideneuridine
  • 2'.3'-Isopropylidene-Uridine,>99%
  • 2',3'-O-Isopropylideneuridine,99%
  • 2',3'-Isopropylideneuridine sopropylideneuridine
  • 1-((3AR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione
  • 2',3'-O-ISOPROPYLIDENEURIDINE USP/EP/BP
  • 1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione(BJPQ-SL-1)
  • 1-[(3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]pyrimidine-2,4-dione
  • 2',3'-O-lsopropylideneuridine
  • 1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dion
  • 2',?3'-?O-?(1-?methylethylidene)?uridine
  • 2',3'-O-Isopropylideneuridine
  • 2',3'-Isopropylideneuridine
  • Troparil Impurity 10
  • 362-43-6
  • C12H16N2O6
  • Biochemicals and Reagents
  • BioChemical
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
  • API intermediates
  • Bases & Related Reagents
  • Nucleotides
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides