ChemicalBook > CAS DataBase List > 2'-O-Methyluridine

2'-O-Methyluridine

Product Name
2'-O-Methyluridine
CAS No.
2140-76-3
Chemical Name
2'-O-Methyluridine
Synonyms
1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxyMethyl)-3-Methoxytetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione;OMe-rU;2'-OMe-Ur;2'-OMe-rU;2-Methyoxy uridine;2'-O-METHYLURIDINE;2'-O-Methyluridine;2 '- Methoxyuridine;2'-O-Methyluridine>Uridine, 2'-O-methyl-
CBNumber
CB8397539
Molecular Formula
C10H14N2O6
Formula Weight
258.23
MOL File
2140-76-3.mol
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2'-O-Methyluridine Property

Melting point:
154-156°C
Density 
1.53±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
9.39±0.10(Predicted)
form 
Powder
color 
White to Off-white
λmax
261nm(MeOH)(lit.)
CAS DataBase Reference
2140-76-3(CAS DataBase Reference)
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
24/25
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2290
Product name
2'-O-Methyluridine
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$65
Updated
2024/03/01
TCI Chemical
Product number
M2290
Product name
2'-O-Methyluridine
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$195
Updated
2024/03/01
Alfa Aesar
Product number
J64897
Product name
2'-O-Methyluridine, 99%
Packaging
1g
Price
$33.3
Updated
2023/06/20
TRC
Product number
M338200
Product name
2''-O-MethylUridine
Packaging
50g
Price
$1245
Updated
2021/12/16
Biosynth Carbosynth
Product number
NM04259
Product name
2'-O-Methyluridine
Packaging
50g
Price
$350
Updated
2021/12/16
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2'-O-Methyluridine Chemical Properties,Usage,Production

Description

2'-O-Methyluridine is an analog of uridine and has been shown to have antiviral and anticancer properties. 2'-O-Methyluridine inhibits protein synthesis by competing with uridine for the active site of the enzyme ribonucleotide reductase, which converts ribonucleotides to dNMPs. This compound also inhibits RNA synthesis by disrupting the pairing of adenine and cytosine residues in RNA strands.

Chemical Properties

White Solid

Uses

Uridine analog. Used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replication.

Uses

Uridine analog. 2'-O-Methyluridine is used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replication.

Definition

ChEBI: A methyluridine that consists of uridine bearing a single methyl substituent located at position O-2' on the ribose ring.

2'-O-Methyluridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-O-Methyluridine Suppliers

Jiangsu Synthgene Biotechnology Co.,Ltd.
Tel
18136497538
Email
znf@syngenebio.com
Country
China
ProdList
901
Advantage
58
Wuhu Huaren Science and Technology Co., Ltd.
Tel
0553-0553-5842013-801 18155347026
Fax
086-553-5843138
Email
sale@huarensh.com
Country
China
ProdList
296
Advantage
64
Wuhu Nuowei Chemical Technology Co., Ltd
Tel
0553-8233716 18055326116
Email
sales@nuowei-chem.com
Country
China
ProdList
949
Advantage
55
Jinan Kabotang Biological Technology Co.,Ltd.
Tel
0531-61320525 15866703830
Email
495745175@qq.com
Country
China
ProdList
6864
Advantage
58
Zhengzhou First biochem technology Co.,Ltd.
Tel
0371-68865717 13213090566
Email
firstbio@126.com
Country
China
ProdList
15
Advantage
58
Shandong utilizing biological technology co., LTD
Tel
15966937598
Fax
3407640895 3071519937
Email
3407650895@qq.com
Country
China
ProdList
1016
Advantage
58
Nugene Biopharm Science (Hangzhou) Co., Ltd.
Tel
13326014885
Email
service@nugene.com.cn
Country
China
ProdList
51
Advantage
58
Shanghai Bolu Biotechnology Co., Ltd
Tel
13062875887 13062875887
Email
3662942976@QQ.com
Country
China
ProdList
298
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
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View Lastest Price from 2'-O-Methyluridine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2'-O-Methyluridine 2140-76-3
Price
US $0.00/Kg/Bag
Min. Order
100g
Purity
98%min HPLC
Supply Ability
10KGS
Release date
2021-06-28
Zhejiang Hengkang Pharmaceutical Co., Ltd.
Product
2'-O-Methyluridine 2140-76-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
500kg per month
Release date
2022-12-27
Hefei Huana Biomedical Technology Co.,Ltd.
Product
2'-OME-rU 2140-76-3
Price
US $0.00/g
Min. Order
100g
Purity
≥98%(HPLC)
Supply Ability
20t
Release date
2023-03-23

2140-76-3, 2'-O-MethyluridineRelated Search:


  • 2'-O-METHYLURIDINE (CHIRAL)
  • 2''-O-METHYLURIDINE CRYSTALLINE
  • 1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidine-2,4-quinone
  • 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidine-2,4-dione
  • 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
  • 2'-O-METHYLURIDINE
  • 1-[(2R,3R,4R,5R)-4-HYDROXY-5-(HYDROXYMETHYL)-3-METHOXYOXOLAN-2-YL]-3H-PYRIMIDINE-2,4-DIONE
  • 2'-O-Methyluridine 98+%
  • 2'-O-Methyluridine, 98.0 %
  • 2-Methyoxy uridine
  • 1-[(2S,3S,4R,5S)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-1,2,3,4-tetrahydropyriMidine-2,4-dione
  • 1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxyMethyl)-3-Methoxytetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione
  • 1-(2-O-Methyl-beta-D-ribofuranosyl)uracil
  • 2'-OMe-Ur
  • 2'-O-Methyluridine&gt
  • Uridine, 2'-O-methyl-
  • 2'-OMe-rU
  • 2'-O-Methyluridine USP/EP/BP
  • 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 2’-O-Methyl uridine, RNA modified nucleoside Um
  • RNA modified nucleoside Um
  • 1-((2S,3S,4S,5S)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
  • 2 '- Methoxyuridine
  • OMe-rU
  • 2'-O-Methyluridine
  • 2140-76-3
  • 2140-79-3
  • 2104-76-3
  • pyrimidine
  • Heterocycle-Pyrimidine series
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Heterocycles
  • Nucleotides
  • Pharmaceutical
  • 2140-76-3
  • Nucleosides
  • Modified(deoxy)nucleoside