DMT-2'O-Methyl-rU Phosphoramidite

Product Name: DMT-2'O-Methyl-rU Phosphoramidite
CAS No.: 110764-79-9
Chemical Name: DMT-2'O-Methyl-rU Phosphoramidite
Synonyms: 2'-OMe-U amidite;2’-OMe -dU Amidite;5'-O-DMT-2'-OMe-U-CE;Cytidine Impurity 15;2'-OMe-Uridine Amidite;2'-OMe-Uridine Amidite;2'-OMe-U Phosphoramidite;2'-OMe-rU Phosphoramidite;2'-OMe-U-CE-Phosphoramidite;5'-O-DMT-2'-O-Me-rU-3'-CEDPA
CBNumber: CB5500323
Molecular Formula: C40H49N4O9P
Formula Weight: 760.82
MOL File: 110764-79-9.mol

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DMT-2'O-Methyl-rU Phosphoramidite Property

storage temp.: Sealed in dry,2-8°C
solubility: DMSO : 100 mg/mL (131.44 mM; Need ultrasonic)
form: powder
pka: 9.39±0.10(Predicted)
color: white to off-white
InChI: InChI=1/C40H49N4O9P/c1-27(2)44(28(3)4)54(51-25-11-23-41)53-36-34(52-38(37(36)49-7)43-24-22-35(45)42-39(43)46)26-50-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37-,38-,54?/s3
InChIKey: UVUOJOLPNDCIHL-XKZJCBTISA-N
SMILES: C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OC)[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C |&1:25,27,36,39,r|

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: U211180
Product name: DMT-2′O-Methyl-rU Phosphoramidite
Purity: configured for PerkinElmer, configured for Polygen
Packaging: 1G
Price: $81.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: U211150
Product name: DMT-2′O-Methyl-rU Phosphoramidite
Purity: configured for ?KTA? and OligoPilot?
Packaging: 2g
Price: $181
Updated: 2024/03/01

Sigma-Aldrich

Product number: U211100
Product name: DMT-2′O-Methyl-rU Phosphoramidite
Purity: ≥99% (31P-NMR)
Packaging: 500g
Price: $32550
Updated: 2024/03/01

Sigma-Aldrich

Product number: U211100
Product name: DMT-2′O-Methyl-rU Phosphoramidite
Purity: ≥99% (31P-NMR)
Packaging: 100g
Price: $8080
Updated: 2022/05/15

Sigma-Aldrich

Product number: U211180
Product name: DMT-2′O-Methyl-rU Phosphoramidite
Purity: configured for PerkinElmer, configured for Polygen
Packaging: 0.5g
Price: $92.7
Updated: 2024/03/01

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DMT-2'O-Methyl-rU Phosphoramidite Chemical Properties,Usage,Production

Characteristics

DMT-2′O-Methyl-rU Phosphoramidite belongs to the class of 2′O-Methyl RNA Phosphoramidites. Its key features include:
High yield of crude oligonucleotides Compatible with DNA synthesis;
Can be employed together with DNA or RNA phosphoramidites in the same synthesis to produce mixmer oligonucleotides;
Recommended deprotection conditions are 8 hours at 55 deg C using concentrated ammonia solution, or with AMA (concentrated ammonia/40% aqueous methylamine I/I, v/v) for 10 minutes at 65 deg C;
Purification and other downstream processing of fully modified 2′OMethyl RNA oligonucleotides are simpler than in the case of RNA, as no special precautions are required to provide protection against nucleolytic degradation;
Synthesis of 2′O-Methyl RNA oligonucleotides is similar to standard DNA synthesis but requires an elongated coupling time (recommended is 6minutes compared to 90 seconds for DNA monomers);
2′O-Methyl RNA phosphoramidites are also available with fast deprotection chemistry.

Uses

DMT-2'O-Methyl-rU Phosphoramidite is a white to off-white powder and is used as a pharmaceutical intermediate for pharmaceutical synthesis and scientific research.

Application

2′O-Methyl RNA nucleoside including DMT-2′O-Methyl-rU Phosphoramidite can be advantageously incorporated in nucleic acid probes with RNA or DNA for in-vivo or in-vitro applications to convey nuclease resistance.The unique combination of properties of 2′O-Methyl RNA had found widespread use in the fields of:
Diagnostic probes
Aptamer and ribozyme development
Mixed 2′O-Methyl-RNA/DNA antisense molecules

DMT-2'O-Methyl-rU Phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

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DMT-2'O-Methyl-rU Phosphoramidite Suppliers

Canada 1 China 162 India 3 Switzerland 1 United Kingdom 2 United States 11 Global 180

Wuhu Huaren Science and Technology Co., Ltd.

Tel: 0553-0553-0553-5842013-801-801 18155347026
Fax: 086-553-5843138
Email: jinhuaren@huarensh.com
Country: China
ProdList: 295
Advantage: 64

Wuhu Nuowei Chemical Technology Co., Ltd

Tel: 0553-8233716 18055326116
Email: kendoll@cqpharm.com
Country: China
ProdList: 645
Advantage: 58

Hefei Huana Biomedical Technology Co.,Ltd

Tel: 17333066501
Email: shengwen.fang@huanaok.com.cn
Country: China
ProdList: 95
Advantage: 58

Hefei Stongbio Co.,Ltd.

Tel: 15555170917
Email: sales@stongbio.com
Country: China
ProdList: 498
Advantage: 58

Nugene Biopharm Science (Hangzhou) Co., Ltd.

Tel: 13326014885
Email: service@nugene.com.cn
Country: China
ProdList: 55
Advantage: 58

Shanghai Bolu Biotechnology Co., Ltd

Tel: 13062875887 13062875887
Email: 3662942976@QQ.com
Country: China
ProdList: 436
Advantage: 58

Asymchem Labs.

Tel: 17347534561; 17347534561
Email: liujingjing0710@asymchem.com.cn
Country: China
ProdList: 434
Advantage: 58

Hongene Biotech Corporation

Tel: 021-64757213
Fax: 86-21-64700613
Email: info@hongene.com
Country: China
ProdList: 672
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9511
Advantage: 66

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

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View Lastest Price from DMT-2'O-Methyl-rU Phosphoramidite manufacturers

Hefei Huana Biomedical Technology Co.,Ltd.

Product: 5'-O-DMT-2'-OMe-U-CE 110764-79-9
Price: US $0.00/mg
Min. Order: 100mg
Purity: ≥98%
Supply Ability: 20tons
Release date: 2023-03-09

R&D Scientific Inc.

Product: 5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite 110764-79-9
Price: US $600.00/g
Min. Order: 1g
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-02-11

SHANGHAI NOVRIBO BIOTECH

Product: 2'-OMe-U CE Phosphoramidite 110764-79-9
Price: US $100.00/kg
Min. Order: 0.009999999776482582kg
Purity: 99%
Supply Ability: 5tons
Release date: 2023-03-20

110764-79-9, DMT-2'O-Methyl-rU PhosphoramiditeRelated Search:

3-Chloropropyltrimethoxysilane Trimethoxypropylsilane 3-Mercaptopropyltriethoxysilane UMP 1-beta-D-Arabinofuranosyluracil N,N-Diisopropylethylamine Trifluridine Doxifluridine Ac-rC Phosphoramidite DMT-2′O-TBDMS-rU Phosphoramidite DMT-dT Phosphoramidite 2'-O-Methyluridine Uridine L-Uridine FLUORESCEIN-DT CEP N-blocked-5'-O-DMT 3'-CED iododeoxyuridine phosphoramidite 5-[E-2-[N-[N-[N1-(4-T-BUTYLBENZOYL)-D-(+)-BIOTINYL]-6-AMINOHEXYL]CARBOXAMIDO]VINYL]-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYURIDINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE 2'-O-METHYL-5-METHYL-U CEP

3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-5-(2,4-DIOXO-3H-PYRIMIDIN-1-YL)-4-METHOXYOXOLA

DMT-2'O-ME-RU AMIDITE 0.5G 89 SINGLE

2'-O-methyluridine-ce phosphoramidite*for abi

DMT-2'O-Me-rU Amidite 10g, Single

DMT-2'O-ME-RU AMIDITE 0.5G AB SINGLE

2’-O-Methy-rUPhosphoramidite

N-blocked-5'-O-DMT-2'-O-Me CED uridine phosphoramidite

5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

5'-O-DMT-2'-O-Me-rU-3'-CEDPA

5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite

2'-Deoxy-2'-O-Me-5'-O-DMT-Uridine-3'-CED PhosphoraMidite

Uridine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-Methyl-, 3'-[2-cyanoethyl bis(1-Methylethyl)phosphoraMidite]

DMT-2′O-Methyl-rU Phosphoramidite

2'-O-Methyl-rU phosphoramidite

5'-DMT-2'-OMe-rU Phosphoramidite

5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine 3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite

5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidit

5'-O-(4, 4'-Dimethoxytrityl)-2'-O-methyl-Uridine-3'-CE-Phosphoramidite

Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

5'-Dimethoxytrityl-Uridine,2'-O-methyl,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

5'-DMTr-2'-O-Me-3'-O-CEP-URIDINE

5'-O-DMT-2'-OMe-rU Phosphoramidite

5'-O-DMT-2'-OMe-Uridine-CE Phosphoramidite

2'-OMe-U amidite

DMT-2-O-ME-U-CE Phosphoramidite

DMT-2'-O-Me-U Phosphoramidite

5'-O-DMT-2'-OMe-U-CE

5'-O-DMT-2'-OMe- Uridine -3’-Cyanoethyl Phosphoramidite

2'-OMe-Uridine Amidite

DMTr-2'-O-Me-rU-3'-CE-Phosphoramidite

2’-OMe -dU Amidite

5'-ODMT-2'-OMe Uridine-3'-OCEPA

2'-OMe-U Phosphoramidite

DMT-2'O-Methyl-rU Phosphoramidite

DMT-2'-O-Me-U-CE Phosphoramidite

5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxy-tetrahydrofuran-3-yl]oxy-(diisopropylamino)phosphanyl]oxypropanenitrile

5'-O-DMT-2'-OMe-Uridine-CE Phosphoramidite

2'-OMe-U-CE-Phosphoramidite

2'-O-Methyl Uridine CED Phosphoramidite

2'-O-Me-5'-O-DMT-U-3'-CE-Phosphoramidite

2'-OMe-rU Phosphoramidite

5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite

2'-Deoxy-2'-O-Me-5'-O-DMT-Uridine-3'-CED Phosphoramidite

5'-O-DMT-2'-OMe- Uridine -3’-Cyanoethyl Phosphoramidite

5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

2'-OMe-Uridine Amidite

Cytidine Impurity 15

110764-79-9