ChemicalBook > CAS DataBase List > DMT-2'O-Methyl-rU Phosphoramidite

DMT-2'O-Methyl-rU Phosphoramidite

Product Name
DMT-2'O-Methyl-rU Phosphoramidite
CAS No.
110764-79-9
Chemical Name
DMT-2'O-Methyl-rU Phosphoramidite
Synonyms
2'-OMe-U amidite;2’-OMe -dU Amidite;5'-O-DMT-2'-OMe-U-CE;Cytidine Impurity 15;2'-OMe-Uridine Amidite;2'-OMe-U Phosphoramidite;2'-OMe-rU Phosphoramidite;2'-OMe-U-CE-Phosphoramidite;5'-O-DMT-2'-O-Me-rU-3'-CEDPA;2’-O-Methy-rUPhosphoramidite
CBNumber
CB5500323
Molecular Formula
C40H49N4O9P
Formula Weight
760.82
MOL File
110764-79-9.mol
More
Less

DMT-2'O-Methyl-rU Phosphoramidite Property

storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO : 100 mg/mL (131.44 mM; Need ultrasonic)
form 
powder
pka
9.39±0.10(Predicted)
color 
white to off-white
biological source
non-animal source (no BSE/TSE risk)
InChI
InChI=1/C40H49N4O9P/c1-27(2)44(28(3)4)54(51-25-11-23-41)53-36-34(52-38(37(36)49-7)43-24-22-35(45)42-39(43)46)26-50-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37-,38-,54?/s3
InChIKey
UVUOJOLPNDCIHL-XKZJCBTISA-N
SMILES
C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OC)[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C |&1:25,27,36,39,r|
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
U211180
Product name
DMT-2′O-Methyl-rU Phosphoramidite
Purity
configured for PerkinElmer, configured for Polygen
Packaging
1G
Price
$84.7
Updated
2025/07/31
Sigma-Aldrich
Product number
U211150
Product name
DMT-2′O-Methyl-rU Phosphoramidite
Purity
configured for ?KTA? and OligoPilot?
Packaging
2g
Price
$188
Updated
2025/07/31
Sigma-Aldrich
Product number
U211140
Product name
DMT-2′O-Methyl-rU Phosphoramidite
Purity
configured for MerMade
Packaging
1 g
Price
$105
Updated
2025/07/31
Sigma-Aldrich
Product number
U211140
Product name
DMT-2′O-Methyl-rU Phosphoramidite
Purity
configured for MerMade
Packaging
1 unit
Price
$191
Updated
2025/07/31
Sigma-Aldrich
Product number
U211140
Product name
DMT-2′O-Methyl-rU Phosphoramidite
Purity
configured for MerMade
Packaging
5 g
Price
$945
Updated
2025/07/31
More
Less

DMT-2'O-Methyl-rU Phosphoramidite Chemical Properties,Usage,Production

Characteristics

DMT-2′O-Methyl-rU Phosphoramidite belongs to the class of 2′O-Methyl RNA Phosphoramidites. Its key features include:
High yield of crude oligonucleotides Compatible with DNA synthesis;
Can be employed together with DNA or RNA phosphoramidites in the same synthesis to produce mixmer oligonucleotides;
Recommended deprotection conditions are 8 hours at 55°C using concentrated ammonia solution, or with AMA (concentrated ammonia/40% aqueous methylamine I/I, v/v) for 10 minutes at 65°C;
Purification and other downstream processing of fully modified 2′OMethyl RNA oligonucleotides are simpler than in the case of RNA, as no special precautions are required to provide protection against nucleolytic degradation;
Synthesis of 2′O-Methyl RNA oligonucleotides is similar to standard DNA synthesis but requires an elongated coupling time (recommended is 6minutes compared to 90 seconds for DNA monomers);
2′O-Methyl RNA phosphoramidites are also available with fast deprotection chemistry.

Uses

DMT-2'O-Methyl-rU Phosphoramidite is a white to off-white powder and is used as a pharmaceutical intermediate for pharmaceutical synthesis and scientific research.

Application

2′O-Methyl RNA nucleoside including DMT-2′O-Methyl-rU Phosphoramidite can be advantageously incorporated in nucleic acid probes with RNA or DNA for in-vivo or in-vitro applications to convey nuclease resistance.The unique combination of properties of 2′O-Methyl RNA had found widespread use in the fields of:
Diagnostic probes
Aptamer and ribozyme development
Mixed 2′O-Methyl-RNA/DNA antisense molecules

DMT-2'O-Methyl-rU Phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

DMT-2'O-Methyl-rU Phosphoramidite Suppliers

Canada 1 China 175 India 4 Switzerland 1 United Kingdom 2 United States 11 Global 194
Wuhu Huaren Science and Technology Co., Ltd.
Tel
0553-5842013-801 18155347026
Fax
086-553-5843138
Email
jinhuaren@huarensh.com
Country
China
ProdList
255
Advantage
64
Wuhu Nuowei Chemical Technology Co., Ltd
Tel
0053-0553-8233716-803 18055326116
Email
sales@nuowei-chem.com
Country
China
ProdList
641
Advantage
58
Hefei Stongbio Co.,Ltd.
Tel
15555170917
Email
sales@stongbio.com
Country
China
ProdList
509
Advantage
58
Nugene Biopharm Science (Hangzhou) Co., Ltd.
Tel
13326014885
Email
service@nugene.com.cn
Country
China
ProdList
55
Advantage
58
Shanghai Bolu Biotechnology Co., Ltd
Tel
13062875887
Email
3662942976@QQ.com
Country
China
ProdList
465
Advantage
58
Tianjin Orilife Biopharma Co.,Ltd.
Tel
15032236037; 17602299400
Email
yangjiaqi@cnorilife.com
Country
China
ProdList
175
Advantage
58
Hongene Biotech Corporation
Tel
021-64757213
Fax
86-21-64700613
Email
info@hongene.com
Country
China
ProdList
672
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Nanjing Baifuli Technology Co., Ltd.
Tel
25-25-58740604 15951658055
Fax
+86-25-58356858
Email
sales@unisyn.cn
Country
China
ProdList
591
Advantage
58
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Wuhan Chemduro Pharm Tech Co. Ltd.
Tel
18040571231/1402788087
Fax
sales@chemduro.com
Country
China
ProdList
1973
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Tianjin Scaxchem Limited Compnay
Tel
18020011318 18630949181
Email
sales@cosychem.com
Country
China
ProdList
642
Advantage
55
Birdo (Shanghai) Medical Technology Co., Ltd.
Tel
021-58099077
Fax
-
Email
sales@birdochem.com
Country
China
ProdList
185
Advantage
55
Wuhu Nuowei Chemical Technology Co., Ltd
Tel
0553-0553-8233716-803-803 18055326116
Email
sales@nuowei-chem.com
Country
China
ProdList
953
Advantage
55
Hangzhou Dingyan Chem Co., LTD
Tel
0571-87157530-8008 17369838938
Fax
0571-87156470
Email
sales@dingyanchem.com
Country
China
ProdList
2386
Advantage
58
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9274
Advantage
55
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
6059
Advantage
65
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Suzhou GenePharma Co., Ltd.
Tel
+86 512 86668828 ,8026
Fax
+86 512 86668828
Email
chem@genepharma.com
Country
China
ProdList
46
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Yihe Biological Technology Co., Ltd.
Tel
021-68882955 17721395025
Fax
021-68882955
Email
2423903095@qq.com
Country
China
ProdList
4991
Advantage
58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-50664929, 13971561712
Fax
027-50664927 / QQ: 3452835437
Email
hubxys2001@163.com
Country
China
ProdList
1437
Advantage
55
Wellman Pharmaceutical Group Limited
Tel
027-027-83778875 15807197853
Fax
027-83991220
Email
15807197853@163.com
Country
China
ProdList
3931
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Fuyang Ziyi Biological Pharmaceutical Co., Ltd.
Tel
19308655899; 19308655899
Fax
-
Email
2677609105@qq.com
Country
China
ProdList
500
Advantage
58
Maanshan geneyan biotech Co.,LTD
Tel
18913822354
Email
market@geneyan-bio.com
Country
China
ProdList
300
Advantage
58
SuZhou Medinoah Co.,LTD.
Tel
0512-69561983 13914027025
Fax
0512-69561982
Email
zhang_q@medinoah.com
Country
China
ProdList
3811
Advantage
58
Shandong utilizing biological technology co., LTD
Tel
15966937598
Fax
3407640895 3071519937
Email
3407650895@qq.com
Country
China
ProdList
2274
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd.
Tel
19981275275
Email
sales@zsdpharm.com
Country
China
ProdList
381
Advantage
58
SHANGHAI SEAGA BIO-TECH CO.,LTD
Tel
13764598896
Email
grace8018@163.com
Country
China
ProdList
289
Advantage
58
Shanghai Xianggeng Technology Development Co. Ltd.
Tel
021-021-56152668 18116302010
Fax
18116300787
Email
sharing@sharingtechcn.com
Country
China
ProdList
506
Advantage
58
Wuhan Boye Technology Development Co., Ltd.
Tel
027-81625225 15377010747
Fax
027-81625225
Email
hui@boyechemicals.com
Country
China
ProdList
495
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
9939
Advantage
58
Hunan chemfish Scientific co.,ltd
Tel
19313119705 15707487186
Email
sales@chemfish.com
Country
China
ProdList
4960
Advantage
58
ROSEWA HOLDING GROUP CO.,LIMITED
Tel
+86-023-62871537
Email
sales@rosewachem.com
Country
China
ProdList
2803
Advantage
58
Zhengzhou Granlen Sciences, ltd.
Tel
0371-85513397 +86-18610099868
Email
info@granlen.com
Country
China
ProdList
1890
Advantage
58
Henan Alfa Chemical Co., Ltd
Tel
+8615838112936
Email
alfa10@alfachem.cn
Country
China
ProdList
12921
Advantage
58
Finetech Industry Limited
Tel
+86-27-8746-5837 +8619945049750
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9629
Advantage
58
NewCan Biotech Limited
Tel
+86-0571-86912261 +8613735419629
Email
sales@newcanbio.com
Country
China
ProdList
9985
Advantage
58
More
Less

View Lastest Price from DMT-2'O-Methyl-rU Phosphoramidite manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 110764-79-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26
Hefei Huana Biomedical Technology Co.,Ltd.
Product
5'-O-DMT-2'-OMe-U-CE 110764-79-9
Price
US $0.00/mg
Min. Order
100mg
Purity
≥98%
Supply Ability
20tons
Release date
2023-03-09
R&D Scientific Inc.
Product
5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite 110764-79-9
Price
US $600.00/g
Min. Order
1g
Purity
98
Supply Ability
500 Kg
Release date
2024-02-11

110764-79-9, DMT-2'O-Methyl-rU PhosphoramiditeRelated Search:

3-Chloropropyltrimethoxysilane Trimethoxypropylsilane 3-Mercaptopropyltriethoxysilane 1-beta-D-Arabinofuranosyluracil N,N-Diisopropylethylamine Trifluridine Doxifluridine Ac-rC Phosphoramidite Uridine 5'-monophosphate DMT-2′O-TBDMS-rU Phosphoramidite DMT-dT Phosphoramidite 2'-O-Methyluridine Uridine L-Uridine FLUORESCEIN-DT CEP N-blocked-5'-O-DMT 3'-CED iododeoxyuridine phosphoramidite 5-[E-2-[N-[N-[N1-(4-T-BUTYLBENZOYL)-D-(+)-BIOTINYL]-6-AMINOHEXYL]CARBOXAMIDO]VINYL]-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYURIDINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE 2'-O-METHYL-5-METHYL-U CEP

  • 3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-5-(2,4-DIOXO-3H-PYRIMIDIN-1-YL)-4-METHOXYOXOLA
  • DMT-2'O-ME-RU AMIDITE 0.5G 89 SINGLE
  • 2'-O-methyluridine-ce phosphoramidite*for abi
  • DMT-2'O-Me-rU Amidite 10g, Single
  • DMT-2'O-ME-RU AMIDITE 0.5G AB SINGLE
  • 2’-O-Methy-rUPhosphoramidite
  • N-blocked-5'-O-DMT-2'-O-Me CED uridine phosphoramidite
  • 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • 5'-O-DMT-2'-O-Me-rU-3'-CEDPA
  • 5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite
  • Uridine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-Methyl-, 3'-[2-cyanoethyl bis(1-Methylethyl)phosphoraMidite]
  • DMT-2′O-Methyl-rU Phosphoramidite
  • 2'-O-Methyl-rU phosphoramidite
  • 5'-DMT-2'-OMe-rU Phosphoramidite
  • 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine 3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite
  • 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidit
  • 5'-O-(4, 4'-Dimethoxytrityl)-2'-O-methyl-Uridine-3'-CE-Phosphoramidite
  • Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
  • 5'-Dimethoxytrityl-Uridine,2'-O-methyl,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • 5'-DMTr-2'-O-Me-3'-O-CEP-URIDINE
  • 5'-O-DMT-2'-OMe-rU Phosphoramidite
  • 5'-O-DMT-2'-OMe-Uridine-CE Phosphoramidite
  • 2'-OMe-U amidite
  • DMT-2-O-ME-U-CE Phosphoramidite
  • DMT-2'-O-Me-U Phosphoramidite
  • 5'-O-DMT-2'-OMe-U-CE
  • 5'-O-DMT-2'-OMe- Uridine -3’-Cyanoethyl Phosphoramidite
  • 2'-OMe-Uridine Amidite
  • DMTr-2'-O-Me-rU-3'-CE-Phosphoramidite
  • 2’-OMe -dU Amidite
  • 5'-ODMT-2'-OMe Uridine-3'-OCEPA
  • 2'-OMe-U Phosphoramidite
  • DMT-2'O-Methyl-rU Phosphoramidite
  • DMT-2'-O-Me-U-CE Phosphoramidite
  • 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxy-tetrahydrofuran-3-yl]oxy-(diisopropylamino)phosphanyl]oxypropanenitrile
  • 2'-OMe-U-CE-Phosphoramidite
  • 2'-O-Methyl Uridine CED Phosphoramidite
  • 2'-O-Me-5'-O-DMT-U-3'-CE-Phosphoramidite
  • 2'-OMe-rU Phosphoramidite
  • 2'-Deoxy-2'-O-Me-5'-O-DMT-Uridine-3'-CED Phosphoramidite
  • 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • Cytidine Impurity 15
  • 5’-O-DMT-2’- OCH 3 -U-CE- Phosphoramidite
  • 2'-O-Methyl Uridine CED Phosphoramidite
  • 5'-O-DMT-2'-OMe-U-CE, 99%, ≤0.2%(K.F.)
  • DMT-2'-0Me-U-CE-Phosphoramidite
  • 5'-O-DMT-2' -O-methyluridine-3'-O-[O-(2-cyanoethyl)-N, N' -diisopropylphosphoramidite, Me-rU Phosphoramidite,
  • 5'-o-[Bis(4-methoxy-phenyl)phenylmethyl]-2'-o-methyl-uridine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
  • 110764-79-9