5-Methyluridine
- Product Name
- 5-Methyluridine
- CAS No.
- 1463-10-1
- Chemical Name
- 5-Methyluridine
- Synonyms
- RIBOTHYMIDINE;1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione;1-(BETA-D-RIBOFURANOSYL)THYMINE;5-Me-U;5-Me-Ur;Methyluridine;5-methyuridine;ribosylthymine;5-methyl-uridin;THYMINERIBOSIDE
- CBNumber
- CB1322473
- Molecular Formula
- C10H14N2O6
- Formula Weight
- 258.23
- MOL File
- 1463-10-1.mol
5-Methyluridine Property
- Melting point:
- 183-184 °C(lit.)
- Density
- 1.576±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Methanol (Slightly, Heated, Sonicated), Water (Sparingly, Sonicated)
- pka
- 9.55±0.10(Predicted)
- form
- powder
- color
- white
- PH
- 9.7
- λmax
- 267 (pH 1);268 (pH 13)
- InChI
- InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
- InChIKey
- DWRXFEITVBNRMK-JXOAFFINSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)[C@H](O)[C@@H]1O
- CAS DataBase Reference
- 1463-10-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- R752002
- Product name
- 5-METHYLURIDINE
- Purity
- AldrichCPR
- Packaging
- 25MG
- Price
- $29.8
- Updated
- 2024/03/01
- Product number
- 535893
- Product name
- 5-Methyluridine
- Purity
- 97%
- Packaging
- 25g
- Price
- $89.3
- Updated
- 2023/06/20
- Product number
- 535893
- Product name
- 5-Methyluridine
- Purity
- 97%
- Packaging
- 100g
- Price
- $235
- Updated
- 2023/06/20
- Product number
- M1405
- Product name
- 5-Methyluridine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $21
- Updated
- 2024/03/01
- Product number
- M1405
- Product name
- 5-Methyluridine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $29
- Updated
- 2024/03/01
5-Methyluridine Chemical Properties,Usage,Production
Description
5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine. It is the ribonucleoside counterpart to the deoxyribonucleoside thymidine, which lacks a hydroxyl group at the 2' position. 5-Methyluridine contains a thymine base joined to a ribose pentose sugar. It is an endogenous methylated nucleoside found in human fluids. In cells, 5-methyluridine is present in tRNA, formed during its post-transcriptional modification by the methylation of uridine.
Chemical Properties
White Powder
Uses
A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.
It enhances the antitumor activity of 5-fluorouracil in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.
Definition
ChEBI: Ribothymidine is a methyluridine having a single methyl substituent at the 5-position on the uracil ring. It has a role as a human metabolite, an Escherichia coli metabolite and an antigen.
5-Methyluridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Methyluridine manufacturers
- Product
- 5-Methyluridine 1463-10-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20Ton
- Release date
- 2024-10-31
- Product
- 5-Methyluridine 1463-10-1
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 1000KGS
- Release date
- 2021-07-02
- Product
- 5-Methyluridine 1463-10-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-05