5-Methyluridine

Product Name: 5-Methyluridine
CAS No.: 1463-10-1
Chemical Name: 5-Methyluridine
Synonyms: RIBOTHYMIDINE;1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione;1-(BETA-D-RIBOFURANOSYL)THYMINE;5-Me-U;5-Me-Ur;Methyluridine;5-methyuridine;ribosylthymine;5-methyl-uridin;THYMINERIBOSIDE
CBNumber: CB1322473
Molecular Formula: C10H14N2O6
Formula Weight: 258.23
MOL File: 1463-10-1.mol

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5-Methyluridine Property

Melting point:: 183-184 °C(lit.)
Density: 1.576±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Methanol (Slightly, Heated, Sonicated), Water (Sparingly, Sonicated)
pka: 9.55±0.10(Predicted)
form: powder
color: white
PH: 9.7
λmax: 267 (pH 1)；268 (pH 13)
InChI: InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
InChIKey: DWRXFEITVBNRMK-JXOAFFINSA-N
SMILES: OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)[C@H](O)[C@@H]1O
CAS DataBase Reference: 1463-10-1(CAS DataBase Reference)

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Safety

Hazard Codes: T+
Risk Statements: 26/27/28
Safety Statements: 24/25
WGK Germany: 3
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R752002
Product name: 5-METHYLURIDINE
Purity: AldrichCPR
Packaging: 25MG
Price: $29.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 535893
Product name: 5-Methyluridine
Purity: 97%
Packaging: 25g
Price: $89.3
Updated: 2023/06/20

Sigma-Aldrich

Product number: 535893
Product name: 5-Methyluridine
Purity: 97%
Packaging: 100g
Price: $235
Updated: 2023/06/20

TCI Chemical

Product number: M1405
Product name: 5-Methyluridine
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $21
Updated: 2024/03/01

TCI Chemical

Product number: M1405
Product name: 5-Methyluridine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $29
Updated: 2024/03/01

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5-Methyluridine Chemical Properties,Usage,Production

Description

5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine. It is the ribonucleoside counterpart to the deoxyribonucleoside thymidine, which lacks a hydroxyl group at the 2' position. 5-Methyluridine contains a thymine base joined to a ribose pentose sugar. It is an endogenous methylated nucleoside found in human fluids. In cells, 5-methyluridine is present in tRNA, formed during its post-transcriptional modification by the methylation of uridine.

Chemical Properties

White Powder

Uses

A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.
It enhances the antitumor activity of 5-fluorouracil in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.

Definition

ChEBI: Ribothymidine is a methyluridine having a single methyl substituent at the 5-position on the uracil ring. It has a role as a human metabolite, an Escherichia coli metabolite and an antigen.

5-Methyluridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Methyluridine Suppliers

Americas 1 Belgium 1 Canada 4 China 344 Europe 3 Germany 8 India 19 Italy 1 Japan 2 Russia 1 Slovakia 1 South Korea 1 Switzerland 3 The Netherlands 1 United Kingdom 16 United States 52 Global 458

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

chemcube

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Email: sales@chemcube.eu
Country: Germany
ProdList: 4083
Advantage: 34

PARAGOS

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Email: info@paragos.com
Country: Germany
ProdList: 6371
Advantage: 39

Service Chemical Inc.

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Email: sales@chemos-group.com
Country: Germany
ProdList: 6350
Advantage: 71

Boehringer Ingelheim GmbH

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Email: finechem@ing.boehringer-ingelheim.com
Country: Germany
ProdList: 116
Advantage: 86

ABCR GmbH & CO. KG

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Email: info@abcr.de
Country: Germany
ProdList: 6831
Advantage: 75

Pharma-Waldhof GmbH

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Country: Germany
ProdList: 184
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View Lastest Price from 5-Methyluridine manufacturers

Xinxiang Aurora Biotechnology Co.,Ltd.

Product: 5-Methyluridine 1463-10-1
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20Ton
Release date: 2024-10-31

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Methyluridine 1463-10-1
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%min
Supply Ability: 1000KGS
Release date: 2021-07-02

Hebei Weibang Biotechnology Co., Ltd

Product: 5-Methyluridine 1463-10-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-05

1463-10-1, 5-MethyluridineRelated Search:

5-Methyluridine 2,2'β-Oxy-2-deoxo-2,3-didehydro-2'-deoxy-5-methyluridine,2,2'-ANHYDRO-5-METHYLURIDINE,O2,2'-Anhydro-5-methyluridine 2'-DEOXY-2'-FLUORO-5-METHYLURIDINE DMT-2'O-Methyl-rU Phosphoramidite 2'-C-Methyluridine 2'-O-METHYL-5-METHYLURIDINE,5-METHY-5-METHYLURIDINE 2'-O-METHYLURIDINE,2''-O-METHYLURIDINE CRYSTALLINE 3-METHYLURIDINE Uridine THYMIDINE 5'-MONOPHOSPHATE, [2-14C] DISODIUM SALT (AA-UTP) SODIUM SALT 5-METHYL-[1'-13C]URIDINE HT MEDIA SUPPLEMENT AMINOALLYL UTP 5'-O-(DIMETHOXYTRITYL)-2'-O-METHYL-5-METHYLURIDINE FLUORESCEIN-12-UTP 5-formyloxymethyluridine THYMIDINE-3',5'-DIPHOSPHATE, DISODIUM SALT

5-methyl-uridin

5-methyuridine

5-Methyluridine (Patent )

THYMINERIBOSIDE

URIDINE, 5-METHYL-

5-METHYLURIDINE(5-Methyl-1-ˉ-ribofuranosyl uracil

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

5-methyluridine/ribothymidine

ribosylthymine/5-methyluridine

5-methyluridine (produced by synthesis)

Methyluridine

5-Me-U

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-5-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione

RibosylthyMine(5-Methyluridine,RibothyMidine)

1-β-D-Ribofuranosylthymine

5-Methyl-1-β-D-ribofuranosyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-quinone

1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione

5-Methyluridine, >=99%

5-Methyluridine≥ 99% (HPLC)

5-METHYLURIDINE

5-METHYL-D-URIDINE

5-METHYL-1-BETA-D-RIBOFURANOSYL URACIL

1-(BETA-D-RIBOFURANOSYL)THYMIDINE

1-(BETA-D-RIBOFURANOSYL)THYMINE

BETA-D-THYMINE RIBOSIDE

BETA-RIBOFURANOSIDE

ribosylthymine

RIBOTHYMIDINE

5-Me-Ur

5-Methyluridine&gt

5-Methyluridine USP/EP/BP

5-Methyluridine extrapure, 98%

5-Methyluridine, RNA modified ribo-nucleoside m5U

5-Methyfuridine

1463-10-1

1436-10-1

1463-10-3

C10H14N2O6

Specialty Synthesis

Nucleosides

Oligonucleotide Synthesis

Nucleosides, Nucleotides, Oligonucleotides

Nucleoside Analogs

BioChemical

Biochemicals and Reagents

Carbohydrates & Derivatives

Heterocycles

Biochemistry

Nucleosides and their analogs

Nucleosides, Nucleotides & Related Reagents

Bases & Related Reagents

Nucleotides

Pyridines, Pyrimidines, Purines and Pteredines

Miscellaneous Biochemicals

Nucleotides and Nucleosides

bc0001