LEUKOTRIENE B4
- Product Name
- LEUKOTRIENE B4
- CAS No.
- 71160-24-2
- Chemical Name
- LEUKOTRIENE B4
- Synonyms
- LTB4;LEUKOTRIENE B4;Leukotriene B?;LTB4 (Leukotriene B4);VNYSSYRCGWBHLG-AMOLWHMGSA-N;Leukotriene B4 MaxSpecStandard;leukotriene B4 ethanol solution;Leukotriene B4 Lipid Maps MS Standard;Leukotriene B - CAS 71160-24-2 - Calbiochem;[5S,12R]-DIHYDROXY-[6Z,8E,10E,14Z]-EICOSATETRAENOIC ACID
- CBNumber
- CB7159905
- Molecular Formula
- C20H32O4
- Formula Weight
- 336.47
- MOL File
- 71160-24-2.mol
LEUKOTRIENE B4 Property
- Boiling point:
- 536.4±50.0 °C(Predicted)
- Density
- 1.040±0.06 g/cm3(Predicted)
- Flash point:
- 14 °C
- storage temp.
- -20°C
- solubility
- Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 50μg/ml)
- pka
- 4.66±0.10(Predicted)
- form
- Clear oil
- color
- Colorless to light yellow
- CAS DataBase Reference
- 71160-24-2(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- L0517
- Product name
- Leukotriene B4
- Purity
- ~100?μg/mL in ethanol, ≥97%
- Packaging
- 10μg
- Price
- $336
- Updated
- 2024/03/01
- Product number
- L0517
- Product name
- Leukotriene B4
- Purity
- ~100?μg/mL in ethanol, ≥97%
- Packaging
- 25μg
- Price
- $531
- Updated
- 2024/03/01
- Product number
- L0517
- Product name
- Leukotriene B4
- Purity
- ~100?μg/mL in ethanol, ≥97%
- Packaging
- 50μg
- Price
- $916
- Updated
- 2024/03/01
- Product number
- 434625
- Product name
- Leukotriene B₄ - CAS 71160-24-2 - Calbiochem
- Packaging
- 50μG
- Price
- $503
- Updated
- 2024/03/01
- Product number
- 20110
- Product name
- Leukotriene B4
- Purity
- ≥97%
- Packaging
- 25μg
- Price
- $144
- Updated
- 2024/03/01
LEUKOTRIENE B4 Chemical Properties,Usage,Production
Description
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-
LTB4 MaxSpec® standard is a quantitative grade standard of LTB4 that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This LTB4 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Uses
LTB4 (Leukotriene B4) is a potent chemokine with roles in inflammation, immunology, the nervous system, brain and skin.
Definition
ChEBI: A leukotriene composed of (6Z,8E,10E,14Z)-icosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
Biological Activity
Potent lipid inflammatory mediator derived from the 5-lipoxygenase pathway of arachidonic acid metabolism. Binds to BLT 1 and BLT 2 receptors and acts as a potent chemotactic agent and activator of leukocytes. Also displays antiviral activity towards DNA viruses and retroviruses.
Biochem/physiol Actions
Proinflammatory agent. Stimulates c-Fos and c-Jun proto-oncogene transcription in human monocytes. Stimulates chemotaxis, aggregation, and degranulation of polymorphonuclear leukocytes.
storage
Store at -20°C
LEUKOTRIENE B4 Preparation Products And Raw materials
Raw materials
Preparation Products
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