3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID
- Product Name
- 3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID
- CAS No.
- 328-69-8
- Chemical Name
- 3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID
- Synonyms
- -Carboxy-5-(trifluoromethyl)phenol;3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID;Benzoic acid, 3-hydroxy-5-(trifluoromethyl)-;3-Carboxy-5-(trifluoromethyl)phenol, 3-Carboxy-5-hydroxybenzotrifluoride
- CBNumber
- CB7171006
- Molecular Formula
- C8H5F3O3
- Formula Weight
- 206.12
- MOL File
- 328-69-8.mol
3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID Property
- Melting point:
- 191-193°C
- Boiling point:
- 333.7±42.0 °C(Predicted)
- Density
- 1.539±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 3.65±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant
- HS Code
- 2918290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H977538
- Product name
- 3-Hydroxy-5-(trifluoromethyl)benzoicacid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- HCH0021956
- Product name
- 3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $693.92
- Updated
- 2021/12/16
- Product number
- HCH0021956
- Product name
- 3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1216.45
- Updated
- 2021/12/16
- Product number
- PC9912
- Product name
- 3-Hydroxy-5-(trifluoromethyl)benzoicacid
- Packaging
- 10g
- Price
- $197
- Updated
- 2021/12/16
- Product number
- 2829-3-35
- Product name
- 3-Hydroxy-5-(trifluoromethyl)benzoic acid
- Purity
- 97%
- Packaging
- 5G
- Price
- $197
- Updated
- 2021/12/16
3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID Chemical Properties,Usage,Production
Synthesis
328-68-7
328-69-8
Step 2: To an aqueous suspension of 3-amino-5-trifluoromethylbenzoic acid (4.36 g, 21.3 mmol) was slowly added concentrated sulfuric acid (10.6 mL, 191 mmol) at 0 °C. The reaction mixture was stirred continuously until the solid was completely dissolved. Subsequently, an aqueous solution (40 mL) of sodium nitrite (1.47 g, 21.3 mmol) was added dropwise. The reaction mixture was continued to be stirred at 0 °C for 15 min, and then warmed up to reflux state maintained for 15 min. Upon completion of the reaction, the mixture was cooled to room temperature and extracted three times with ether. All organic layers were combined, washed with saturated brine and dried over anhydrous magnesium sulfate. The desiccant was removed by filtration and the filtrate was concentrated under reduced pressure to give 3-hydroxy-5-(trifluoromethyl)benzoic acid (25-2, 4.06 g) as a yellow solid.
References
[1] Patent: WO2007/64045, 2007, A1. Location in patent: Page/Page column 341-342
[2] Patent: US2018/312523, 2018, A1. Location in patent: Paragraph 1842; 1844
3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID Suppliers
- Tel
- +91 9891111994
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- Country
- India
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View Lastest Price from 3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID manufacturers
- Product
- 3-Hydroxy-5-(trifluoromethyl)benzoic acid 328-69-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.0%
- Supply Ability
- 100 tons
- Release date
- 2022-02-20