3-Chloro-4-methylphenyl isocyanate
- Product Name
- 3-Chloro-4-methylphenyl isocyanate
- CAS No.
- 28479-22-3
- Chemical Name
- 3-Chloro-4-methylphenyl isocyanate
- Synonyms
- 3-Chlor-p-tolylisocyanat;3-chloro-p-tolyl isocyanate;2-CHLORO-4-ISOCYANATO-TOLUENE;3-Chloro-4-MethylPhenylIsocynate;3-CHLORO-4-METHYLPHENYL ISOCYANATE;3-Chlore-4-methylphenyl isocyanate;Isocyanato-3-chloro-4-methyl benzene;3-Chloro-4-methylphenylIsocyanate>3-Chloro-4-methylphenyl isocyanate-98%;3-Chloro-4-methylphenyl isocyanate ,99%
- CBNumber
- CB7172841
- Molecular Formula
- C8H6ClNO
- Formula Weight
- 167.59
- MOL File
- 28479-22-3.mol
3-Chloro-4-methylphenyl isocyanate Property
- Melting point:
- 20-24℃
- Boiling point:
- 107 °C/3 mmHg (lit.)
- Density
- 1.224 g/mL at 25 °C (lit.)
- vapor pressure
- 13.5Pa at 25℃
- refractive index
- n20/D 1.557(lit.)
- Flash point:
- 229 °F
- storage temp.
- 2-8°C
- form
- Liquid or Low Melting Solid
- color
- Colorless to yellow
- Sensitive
- Moisture Sensitive
- BRN
- 2690771
- LogP
- 3.78
- CAS DataBase Reference
- 28479-22-3(CAS DataBase Reference)
- EPA Substance Registry System
- 3-Chloro-4-methylphenyl isocyanate (28479-22-3)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38-42
- Safety Statements
- 23-26-36/37-45
- RIDADR
- UN 2206 6.1/PG 3
- WGK Germany
- 1
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29291090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H330Fatal if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 478245
- Product name
- 3-Chloro-4-methylphenyl isocyanate
- Purity
- 98%
- Packaging
- 5g
- Price
- $51.59
- Updated
- 2025/07/31
- Product number
- I0563
- Product name
- 3-Chloro-4-methylphenyl Isocyanate
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $54
- Updated
- 2025/07/31
- Product number
- I0563
- Product name
- 3-Chloro-4-methylphenyl Isocyanate
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $160
- Updated
- 2025/07/31
- Product number
- C349925
- Product name
- 3-Chloro-4-methylphenyl isocyanate
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 267397
- Product name
- 3-Chloro-4-methylphenyl isocyanate
- Packaging
- 5g
- Price
- $382
- Updated
- 2021/12/16
3-Chloro-4-methylphenyl isocyanate Chemical Properties,Usage,Production
Description
Chloromethyl phenyl isocyanate is a colorlessto yellow liquid or beige, low-melting solid. Molecularweight =167.59; Melting point =143℃; Vaporpressure =Very low; Flash point ≥ 93℃. Soluble in water;solubility =33 mg/L at 25℃. Insoluble in water
Chemical Properties
Chloromethyl phenyl isocyanate is a colorless to yellow liquid or beige, low-melting solid. Acrid odor.
Uses
3-Chloro-4-methylphenyl isocyanate may be used in the synthesis of the following urea compounds:
- 1-(1-(1-adamantyl)methyl)-3-(3-chloro-4-methylphenyl)urea
- 1-(3-chloro-4-methylphenyl)-3-heptylurea
- 1-(3-chloro-4-methylphenyl)-3-cyclooctylurea
- 1-(3-chloro-4-methylphenyl)-3-(3-fluorobenzyl)urea
- 1-(3-chloro-4-methylphenyl)-3-(4-phenylbutan-2-yl)urea
General Description
A colorless liquid with an acrid odor. Denser than water. Contact may irritate skin, eyes and mucous membranes. Flash point 132°F. Toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.
Air & Water Reactions
Flammable. 3-Chloro-4-methylphenyl isocyanate decomposes in water. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff.
Reactivity Profile
Isocyanates and thioisocyanates, such as 3-Chloro-4-methylphenyl isocyanate, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].
Health Hazard
TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
Potential Exposure
This material is used in organic synthesis.
First aid
If chloromethyl phenyl isocyanate gets into theeyes, remove any contact lenses at once and irrigate immediately for at least 15 min, occasionally lifting upper andlower lids. Seek medical attention immediately. If thischemical contacts the skin, remove contaminated clothingand wash immediately with soap and water. Seek medicalattention immediately. If this chemical has been inhaled,remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped.Transfer promptly to a medical facility. When this chemicalhas been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit
storage
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with chloromethyl phenyl isocyanate you should be trained on itsproper handling and storage. Chloromethyl phenyl isocyanate must be stored to avoid contact with acids (such ashydrochloric and nitric), alkalis (such as sodium hydroxideand potassium hydroxide), and amines (like ammonia),since violent reactions occur. Store in tightly closedcontainers in a cool, well-ventilated area away from heat,light, and moisture. Do not store at temperatures above30℃/86F. Sources of ignition, such as smoking and openflames, are prohibited where 3-Chloro-4-methyl phenyl isocyanate is used, handled, or stored in a manner that couldcreate a potential fire or explosion hazard
Shipping
UN22363-Chloro-4-methylphenyl isocyanate, liquid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Incompatibilities
May form explosive mixture with air. Isocyanates are highly flammable and reactive with many compounds, even with themselves. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Reaction with moist air, water or alcohols may form amines and insoluble polyureas and react exothermically, releasing toxic, corrosive, or flammable gases, including carbon dioxide; and, at the same time, may generate a violent release of heat increasing the concentration of fumes in the air. Incompatible with amines, aldehydes, alkali metals, ammonia, carboxylic acids, caprolactum, alkaline materials, glycols, ketones, mercaptans, hydrides, organotin catalysts, phenols, strong acids, strong bases, strong reducing agents such as hydrides, urethanes, ureas. Elevated temperatures or contact with acids, bases, tertiary amines, and acyl-chlorides may cause explosive polymerization. Attacks some plastics, rubber, and coatings. Contact with metals may evolve flammable hydrogen gas. May accumulate static electrical charges, and may cause ignition of its vapors. Do not store in temperatures above 30C/86F.
3-Chloro-4-methylphenyl isocyanate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Chloro-4-methylphenyl isocyanate manufacturers
- Product
- 3-Chloro-4-methylphenyl isocyanate 28479-22-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25
- Product
- 2-chloro-4-isocyanato-1-methylbenzene 28479-22-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25