ChemicalBook > CAS DataBase List > (2R,3S)-N-Benzoyl-3-phenyl Isoserine

(2R,3S)-N-Benzoyl-3-phenyl Isoserine

Product Name
(2R,3S)-N-Benzoyl-3-phenyl Isoserine
CAS No.
132201-33-3
Chemical Name
(2R,3S)-N-Benzoyl-3-phenyl Isoserine
Synonyms
taxol side chain;TAXOL(R) SIDE CHAIN;Paclitaxel Impurity 30;Paclitaxel Impurity N1;Taxol side chain alcohol;TAXOL SIDE CHAIN ACID(SH);SIDE CHAINS OF PACLITAXEL--4;(2R,3S)-3-Benzoylamino-2-Hydro;(2R,3S)-N-Benzoylphenylisoserine;Paclitaxel Side Chain Impurity 1
CBNumber
CB7172977
Molecular Formula
C16H15NO4
Formula Weight
285.3
MOL File
132201-33-3.mol
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(2R,3S)-N-Benzoyl-3-phenyl Isoserine Property

Melting point:
169-172 °C (lit.)
Boiling point:
580.7±50.0 °C(Predicted)
Density 
1.316±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Acetonitrile (Slightly), DMSO (Slightly), Ethanol (Slightly)
form 
Solid
pka
3.40±0.17(Predicted)
color 
White to Off-White
optical activity
[α]20/D 40°, c = 1.0 in ethanol
CAS DataBase Reference
132201-33-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29242990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
444375
Product name
N-Benzoyl-(2R,3S)-3-phenylisoserine
Purity
98%
Packaging
500mg
Price
$351
Updated
2024/03/01
TRC
Product number
B208550
Product name
(2R,3S)-N-Benzoyl-3-phenylIsoserine
Packaging
1g
Price
$360
Updated
2021/12/16
ChemScene
Product number
CS-0022559
Product name
N-Benzoyl-(2R,3S)-3-phenylisoserine
Purity
99.97%
Packaging
10mg
Price
$50
Updated
2021/12/16
AK Scientific
Product number
Q744
Product name
N-Benzoyl-(2R,3S)-3-phenylisoserine
Packaging
1g
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB151111
Product name
N-Benzoyl-(2R,3S)-3-amino-2-hydroxy-3-phenyl-propionicacid
Packaging
50mg
Price
$51
Updated
2021/12/16
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(2R,3S)-N-Benzoyl-3-phenyl Isoserine Chemical Properties,Usage,Production

Uses

(2R,3S)-N-Benzoyl-3-phenylisoserine is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-N-Benzoyl-3-phenylisoserine shows cytotoxic, antiviral and immunomodulatory activity.

Uses

The presence of this chiral side chain has proven to be essential for the biological activity of taxol, one of the most promising anticancer agents being investigated. The challenging synthesis of taxol has stimulated interest in the attachment of the C-13 side chain to naturally derived taxanes like baccatin III.

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R,3S)-N-Benzoyl-3-phenyl Isoserine Suppliers

Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from (2R,3S)-N-Benzoyl-3-phenyl Isoserine manufacturers

Honest Joy Holdings Limited
Product
N-Benzoyl-(2R,3S)-3-phenylisoserine 132201-33-3
Price
US $0.00/KG
Min. Order
1KG
Purity
97.0%
Supply Ability
100 tons
Release date
2022-01-25
Career Henan Chemical Co
Product
(2R,3S)-N-Benzoyl-3-phenyl Isoserine 132201-33-3
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg , 5kg, 50kg
Release date
2020-01-17

132201-33-3, (2R,3S)-N-Benzoyl-3-phenyl IsoserineRelated Search:


  • N-BENZOYL-(2R,3S)-3-AMINO-2-HYDROXY-3-PHENYL-PROPIONIC ACID
  • N-BENZOYL-(2R,3S)-3-PHENYLISOSERINE
  • TAXOL(R) SIDE CHAIN
  • (2R,3S)-3-Benzoylamino-2-Hydro
  • (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropionacid
  • Taxol side chain alcohol
  • (2R, 3S)-3-BENZOYLAMINO-2-HYDROXY-3-PHENYLPROPIONACID,98+%
  • (2R,3S)-3-Benzoylamino-2-hydroxy-3-phenylpropionic acid
  • SIDE CHAINS OF PACLITAXEL--4
  • (2R,3S)-2-Hydroxy-3-(benzoylamino)-3-phenylpropionic acid
  • (2R,3S)-3-(Benzoylamino)-3-phenyl-2-hydroxypropanoic acid
  • (2R,3S)-N-Benzoylphenylisoserine
  • (2R,3S)-N-Benzoyl-3-phenyl Isoserine
  • (2R,3S)-N-Benzoyl-3-phenylisoserine
  • (2R,3S)-3-(benzoylaMino)-2-hydroxy-3-phenylpropanoate
  • N-benzoyl-(3S,2R)-3-phenylisoserine
  • (αR,βS)-β-(BenzoylaMino)-α-hydroxybenzenepropanoic Acid
  • [R-(R*,S*)]-β-(benzoylaMino)-α-hydroxybenzenepropanoic Acid
  • (2R,3S)-3-BenzaMido-2-hydroxy-3-phenylpropanoic acid
  • N-Benzoyl-(2R,3S)-3-phenylisoserine (2R,3S)-3-Benzoylamino-2-hydroxy-3-phenylpropionic acid
  • N-Benzoyl-(2R,3S)-3-phenylisoserine 98%
  • TAXOL SIDE CHAIN ACID(SH)
  • Paclitaxel Side Chain Impurity 1
  • Paclitaxel Impurity 30
  • taxol side chain
  • Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (αR,βS)-
  • Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (αR,βS)-
  • (2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoic Acid ((2R,3S)-N-Benzoyl-3-phenylisoserine)
  • N-Benzoyl-(2R,3S)-3-phenylisoserine,taxol side chain
  • Paclitaxel Impurity N1
  • 132201-33-3
  • 132201-33-2
  • C6H5CONHCHC6H5CHOHCO2H
  • Unnatural Amino Acid Derivatives
  • Serine Derivatives
  • Specialty Synthesis
  • Peptide Synthesis
  • Herb extract
  • Serine Derivatives
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives
  • Amino Acids & Derivatives
  • Anti-virals
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals