Dibenzoylmethane

Product Name: Dibenzoylmethane
CAS No.: 120-46-7
Chemical Name: Dibenzoylmethane
Synonyms: DBM;1,3-diphenylpropane-1,3-dione;1,3-DIPHENYL-1,3-PROPANEDIONE;karenzudk2;phenylphenacylketone;Phenyl phenacyl ketone;1,3-Diphenylpropanedione;1,3-diphenyl-3-propanedione;DBM83;dppd-h
CBNumber: CB7175433
Molecular Formula: C15H12O2
Formula Weight: 224.25
MOL File: 120-46-7.mol

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Dibenzoylmethane Property

Melting point:: 77-79 °C(lit.)
Boiling point:: 219-221 °C18 mm Hg(lit.)
Density: 0.800 g/cm3
vapor pressure: 0.01Pa at 20℃
refractive index: 1.6600 (estimate)
Flash point:: 219-221°C/18mm
storage temp.: Store below +30°C.
solubility: Chloroform (Slightly), Methanol (Slightly, Sonicated)
pka: 8.95±0.10(Predicted)
form: Crystals
color: Light yellow to yellow
Water Solubility: It is Soluble in ether, chloroform, and aqueous sodium hydroxide. Insoluble in water.
Merck: 14,3009
BRN: 514910
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: NZZIMKJIVMHWJC-UHFFFAOYSA-N
LogP: 4.59 at 25℃
CAS DataBase Reference: 120-46-7(CAS DataBase Reference)
NIST Chemistry Reference: 1,3-Propanedione, 1,3-diphenyl-(120-46-7)
EPA Substance Registry System: 1,3-Propanedione, 1,3-diphenyl- (120-46-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25
WGK Germany: 3
RTECS: TZ1930000
Hazard Note: Irritant
TSCA: Yes
HS Code: 29143900
Toxicity: rat,LD,oral,> 500mg/kg (500mg/kg),National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 28, 1953.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D33454
Product name: 1,3-Diphenyl-1,3-propanedione
Purity: 98%
Packaging: 25g
Price: $56.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: D33454
Product name: 1,3-Diphenyl-1,3-propanedione
Purity: 98%
Packaging: 100g
Price: $196.65
Updated: 2025/07/31

TCI Chemical

Product number: D0910
Product name: 1,3-Diphenyl-1,3-propanedione
Purity: >98.0%(GC)
Packaging: 25g
Price: $20
Updated: 2025/07/31

TCI Chemical

Product number: D0910
Product name: 1,3-Diphenyl-1,3-propanedione
Purity: >98.0%(GC)
Packaging: 100g
Price: $38
Updated: 2025/07/31

TCI Chemical

Product number: D0910
Product name: 1,3-Diphenyl-1,3-propanedione
Purity: >98.0%(GC)
Packaging: 500g
Price: $116
Updated: 2025/07/31

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Dibenzoylmethane Chemical Properties,Usage,Production

Chemical Properties

Dibenzoylmethane (DB), a minor constituent of the root extract of licorice, belongs to the flavonoid family. It is a colorless rhombus flake crystal or yellowish-white powder. soluble in chlorohydrin and chloroform, soluble in sodium hydroxide solution, insoluble in sodium carbonate solution, and very slightly soluble in water. It is used as a colorimetric reagent for the determination of uranium.

Occurrence

Dibenzoylmethane(DBM) is a 1,3-diketone derivative of acetylacetone that has both methyl groups replaced with phenyl groups.Although smaller in size and lacking hydroxyl and methoxy groups，DBM resembles the turmeric spice curcumin (CUR),a diferuloylmethane. Both molecules are metal-chelating agents，contain a B-diketone flanked by two aryl groups,and exhibit anti-proliferative and anticarcinogenic activity. In addition to sharing structural similarity with DBM,CUR,which is also a naturally occurring compound is found in the plant Curcuma longa and has numerous medicinal uses.
DBM and its many naturally occurring derivatives are minor constituentsof licorice. DBM has been isolated from licorice root extracts and otherspecies of Glycyrrhiza.

Uses

Dibenzoylmethane is a new kind of PVC heat stabilizer, it has better transparency, nontoxic and odorless. In case of combined use with Calcium/Zinc, Barium/Zin and other heat stabilizer, it can greatly improve the initial color, transparency, long term stability of PVC, and also can improve the precipitation and “zinc burning” problem during the process. It has very good synergy with zinc soaps, and can protect the PVC color. This material can absorb UV at 290nm, which has the effect as light stabilizer and act as long term stabilizer for PVC products.

Uses

Dibenzoylmethane is a compound known to inhibit tumorigenesis in mice.

Definition

ChEBI: Dibenzoylmethane is a beta-diketone that is acetylacetone (acac) in which both methyl groups have been replaced by phenyl groups. It is a minor constituent of the root extract of licorice (Glycyrrhiza glabra) and exhibits antimutagenic and anticancer effects. It has a role as an antineoplastic agent, a metabolite and an antimutagen. It is a beta-diketone and an aromatic ketone.

Preparation

dibenzoylmethane is prepared by condensation of ethyl benzoate with acetophenone.

Synthesis Reference(s)

Tetrahedron Letters, 37, p. 3885, 1996 DOI: 10.1016/0040-4039(96)00689-2
Chemical and Pharmaceutical Bulletin, 29, p. 2762, 1981 DOI: 10.1248/cpb.29.2762

Flammability and Explosibility

Non flammable

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating vapors

Purification Methods

Dibenzoylmethane (1,3-diphenyl-1,3-propanedione) [120-46-7] M 224.3, m 8 0o. Crystallise dibenzoylmethane from pet ether or MeOH. [Beilstein 7 IV 2512.]

Dibenzoylmethane Preparation Products And Raw materials

Raw materials

Preparation Products

3,5-DIPHENYLPYRAZOLE

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View Lastest Price from Dibenzoylmethane manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Dibenzoylmethane 120-46-7
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-12

Hebei Chuanghai Biotechnology Co., Ltd

Product: Dibenzoylmethane 120-46-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-30

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Dibenzoylmethane 120-46-7
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-14

120-46-7, DibenzoylmethaneRelated Search:

Benzhydrylamine 4,4'-Methylenedianiline Biphenyl Bromodiphenylmethane Diphenylmethane Triformylmethane Chlorodiphenylmethane Benzophenone hydrazone diphenylmethanimine hydrochloride Benzophenone imine Diphenyldiazomethane 1,3-DIPHENYLPROPANETRIONE 1,3-BIS(4-METHOXYPHENYL)-1,3-PROPANEDIONE ISOPROPYL DIBENZOYLMETHANE Tris(dibenzoylmethane)mono (phenanthroline) erbium(III),Tris(dibenzoylmethane)mono(phenanthroline)erbium TRIS(DIBENZOYLMETHANE)MONO(PHENANTHROLINE)EUROPIUM (III) 1,3-DIPHENYLPROPANE 1-(2-HYDROXYPHENYL)-3-PHENYL-1,3-PROPANEDIONE

,3-Diphenyl-propane-1,3-dione

1,3-Diphenyl-1,3-propanediamine

1,3-diphenyl-3-propanedione

1,3-Diphenylpropanedione

Phenyl-hydroxystyrylketone

phenylphenacylketone

rhodiastab83

DBM

DIBENZOYLMETHANE

1,3-diphenylpropane-1,3-dione

1,3-DIPHENYL-1,3-PROPANEDIONE

1,3-Diphenyl-1,3-propanedione~Dppd-H

DIBENZOYLMMETHANE 98% (GC) &

Dibenzoylmethane,>99%

1,3-Propanedione, 1,3-diphenyl-

dppd-h

2-Benzoylacetophenone

3-Propanedione,1,3-diphenyl-1

arenzu dk 2

-Benzoylacetophenone

-Benzoylace-tophenone

Dibenzoylmethan

hodiastab 83

-Hydroxy-chalkone

karenzudk2

omega-Benzoylacetophenone

Phenyl phenacyl ketone

Dibenzoylmethane, 98+%

DIBENZOYLMETHANE extrapure

Karenz DK 2

Phenacyl phenyl ketone

1,3-Diphenyl-1,3-propanedione, 98+%

Dibenzoylmethane,1,3-Diphenyl-1,3-propanedione

1,3-Diphenyl-1,3-propanedione,Dibenzoylmethane

DibenzoylMethane, 98% 100GR

DibenzoylMethane, 98% 10GR

DibenzoylMethane, 98% 25GR

DibenzoylMethane (DBM)

1,3-Diphenyl-1,3-propanedione 98%

DibenzoylMethane, 97+%

(Z)-3-hydroxy-1,3-diphenyl-2-propen-1-one

Dibenzoylmethane in stock Factory

1,3-Diphenylpropane-1,3-dione 99%

Dibenzoylmethane, 98%, for synthesis

1,3-Diphenyl-1,3-propanedione &gt

1,3-DIPHENYL-1,3-PROPANEDIONE FOR SYNTHE

ibenzoylmethane

TIANFU-CHEM CAS:120-46-7 Dibenzoylmethane

2-Aminoacetophenone 551-93-9

1,3-Diphenyl-1,3-propanedione, ≥ 98.0%

DBM83

120-46-7

120-47-7

41451-95-7

83120-46-7

1877-06-0

C6H5CO2CH2

C6H5COCH2COC6H5