(4-OXO-4-PHENYL-BUTYL)-CARBAMIC ACID TERT-BUTYL ESTER
- Product Name
- (4-OXO-4-PHENYL-BUTYL)-CARBAMIC ACID TERT-BUTYL ESTER
- CAS No.
- 116437-41-3
- Chemical Name
- (4-OXO-4-PHENYL-BUTYL)-CARBAMIC ACID TERT-BUTYL ESTER
- Synonyms
- 4-(Boc-amino)-1-phenyl-butan-1-o;4-(Boc-amino)-1-phenyl-1-butanone;4-(BOC-AMINO)-1-PHENYL-BUTAN-1-ONE;4-(N-BOC-Amino)-1-phenylbutan-1-one;tert-butyl 4-oxo-4-phenylbutylcarbaMate;tert-Butyl N-(4-oxo-4-phenylbutyl)carbamate;(4-Oxo-4-phenyl-butyl)-carbamic acid tert-butyl;1,1-Dimethylethyl N-(4-oxo-4-phenylbutyl)carbamate;(4-OXO-4-PHENYL-BUTYL)-CARBAMIC ACID TERT-BUTYL ESTER;N-(4-oxo-4-phenylbutyl)carbaMic acid tert-butyl ester
- CBNumber
- CB7198829
- Molecular Formula
- C15H21NO3
- Formula Weight
- 263.33
- MOL File
- 116437-41-3.mol
(4-OXO-4-PHENYL-BUTYL)-CARBAMIC ACID TERT-BUTYL ESTER Property
- Melting point:
- 90-91°C
- Boiling point:
- 406.8±28.0 °C(Predicted)
- Density
- 1.058±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 12.66±0.46(Predicted)
- Appearance
- White to pink Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B810083
- Product name
- tert-Butyl(4-Oxo-4-phenylbutyl)carbamate
- Packaging
- 250mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 4656-1-72
- Product name
- tert-Butyl N-(4-oxo-4-phenylbutyl)carbamate
- Purity
- 98.0%
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- CS-M1642
- Product name
- Carbamicacid,N-(4-oxo-4-phenylbutyl)-,1,1-dimethylethylester
- Packaging
- 5g
- Price
- $167
- Updated
- 2021/12/16
- Product number
- CS-M1642
- Product name
- Carbamicacid,N-(4-oxo-4-phenylbutyl)-,1,1-dimethylethylester
- Packaging
- 10g
- Price
- $306
- Updated
- 2021/12/16
- Product number
- 2693AA
- Product name
- tert-Butyl(4-oxo-4-phenylbutyl)carbamate
- Packaging
- 5g
- Price
- $327
- Updated
- 2021/12/16
(4-OXO-4-PHENYL-BUTYL)-CARBAMIC ACID TERT-BUTYL ESTER Chemical Properties,Usage,Production
Synthesis
85909-08-6
100-58-3
116437-41-3
Step A: Preparation of tert-butyl N-(4-oxo-4-phenylbutyl)carbamate: tert-butyl 2-oxo-pyrrolidine-1-carboxylate (7.03 g, 38 mmol) was dissolved in tetrahydrofuran (130 mL) and cooled to -78°C. Phenylmagnesium bromide (1.0 M solution, 50 mL) was slowly added at -78 °C. The reaction mixture was stirred at -78 °C for 2 h before the reaction was quenched with 2 M hydrochloric acid solution (35 mL). Subsequently, the reaction mixture was slowly warmed to room temperature and the aqueous layer was extracted with ethyl acetate (2 x 100 mL). The organic phases were combined, washed with saturated brine (50 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 9.56 g of the title compound in 96% yield.
References
[1] Patent: WO2006/44825, 2006, A2. Location in patent: Page/Page column 55
[2] Patent: US2012/184542, 2012, A1. Location in patent: Page/Page column 109
[3] Organic Letters, 2011, vol. 13, # 16, p. 4348 - 4351
(4-OXO-4-PHENYL-BUTYL)-CARBAMIC ACID TERT-BUTYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (4-OXO-4-PHENYL-BUTYL)-CARBAMIC ACID TERT-BUTYL ESTER manufacturers
- Product
- (4-OXO-4-PHENYL-BUTYL)-CARBAMIC ACID TERT-BUTYL ESTER 116437-41-3
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-02-20