ChemicalBook > CAS DataBase List > 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate

3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate

Product Name
3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate
CAS No.
641569-96-2
Chemical Name
3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate
Synonyms
NILOTINIB IMPURITY 22;Nilotinib Impurity 35;Nilotinib Impurity(Nitrate);Nilotinib Impurity 16(Nitrate);ethyl 3-guanidino-4-methylbenzoate;Ethyl 3-guanidino-4-methylbenzoate nitrate;Ethyl 3-Carbamimidoylamino-p-toluate Nitrate;2-Methyl-5-(ethylcarboxy)phenylguanidine nitrate;Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate;3-Carbamimidoylamino-p-toluic Acid Ethyl Ester Nitrate
CBNumber
CB72128666
Molecular Formula
C11H16N4O5
Formula Weight
284.27
MOL File
641569-96-2.mol
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3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate Property

Melting point:
197.0 to 201.0 °C
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
color 
White to Almost white
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Safety

HS Code 
2925.29.9000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1079
Product name
Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate
Purity
>97.0%(HPLC)(T)
Packaging
1g
Price
$36
Updated
2024/03/01
TCI Chemical
Product number
E1079
Product name
Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate
Purity
>97.0%(HPLC)(T)
Packaging
5g
Price
$164
Updated
2024/03/01
Matrix Scientific
Product number
095837
Product name
Ethyl 3-guanidino-4-methylbenzoate nitrate
Purity
95+%
Packaging
250mg
Price
$213
Updated
2021/12/16
Ark Pharm
Product number
AK102656
Product name
Ethyl3-guanidino-4-methylbenzoatenitrate
Purity
97%
Packaging
25g
Price
$74
Updated
2021/12/16
Matrix Scientific
Product number
095837
Product name
Ethyl 3-guanidino-4-methylbenzoate nitrate
Purity
95+%
Packaging
1g
Price
$471
Updated
2021/12/16
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3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate Chemical Properties,Usage,Production

Chemical Properties

3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate Appearance white to almost white powder to crystals, melting point 199 °C, storage 2-8 °C.

Uses

3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate is an organic synthetic material or pharmaceutical intermediate compound that can be used in the preparation of N-phenyl-2-pyrimidinamine derivatives and in the synthesis of nilotinib and its salts. Nilotinib is a tyrosine kinase inhibitor used for the treatment of drug-resistant chronic myelogenous leukemia (CML), and in particular, for the treatment of chronic phase and accelerated phase Philadelphia chromosome positive chronic myeloid leukemia (CML) in adult patients whose disease has progressed on or who cannot tolerate other therapies that included imatinib. Nilotinib is administrated as a hydrochloride salt in the form of capsules that are marketed in the USA and the EU under the name Tasigna?.

3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate Suppliers

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View Lastest Price from 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate manufacturers

Nanjing Fred Technology Co., Ltd
Product
3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate 641569-96-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-20
Career Henan Chemical Co
Product
3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate 641569-96-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-13

641569-96-2, 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrateRelated Search:

N,N-Dimethyl-1,4-phenylenediamine Hexamethyleneimine Tris(hydroxymethyl)aminomethane Ethyl 4-hydroxybenzoate,sodium salt Glycine Tris(trimethylsilyl)phosphate Ethyl benzoate Ethyl acetate Ethylparaben Nilotinib Impurity 7 Nilotinib genotoxic impurity 3 Nilotinib Impurity 1 Nilotinib Impurity 20 3-Amino-4-methylbenzoic acid Nilotinib Impurity 28 Nilotinib impurity 3 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamide Methyl methacrylate

  • 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate
  • 3-[(AMinoiMinoMethyl)aMino]-4-Methylbenzoic acid ethyl ester Mon
  • Ethyl 3-guanidino-4-methylbenzoate nitrate
  • Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate
  • 3-[(Aminoimethyl)amino]-4-methylbenzoic acid ethyl estermononitrate
  • ((aminoiminomethyl)amino)-4-methylbenzoic acid ethyl ester mononitrate
  • ethyl 3-guanidino-4-methylbenzoate
  • 3-(hydrazinylmethylideneamino)-4-methylbenzoic acid ethyl ester
  • NILOTINIB IMPURITY 22
  • Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate &gt
  • 3-Carbamimidoylamino-4-methylbenzoic Acid Ethyl Ester Nitrate
  • 3-Carbamimidoylamino-p-toluic Acid Ethyl Ester Nitrate
  • Ethyl 3-Carbamimidoylamino-p-toluate Nitrate
  • Nilotinib Impurity 35
  • Nilotinib Impurity 16(Nitrate)
  • 2-Methyl-5-(ethylcarboxy)phenylguanidine nitrate
  • Ethyl 3-[(Diaminomethylidene)amino]-4-methylbenzoate Nitrate
  • Benzoic acid, 3-[(aminoiminomethyl)amino]-4-methyl-, ethyl ester, nitrate (1:1)
  • 3-[(aminoiminomethyl)amino]-4-methyl-Benzoic acid ethyl ester nitrate (1:1)
  • 3-[(AMINOIMINOMETHYL)AMINO]-4-METHYL ENZOICACIDMETHYLESTERMONONITRATE
  • Nilotinib Impurity(Nitrate)
  • 641569-96-2
  • C11H15N3O2HNO3