3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate
- Product Name
- 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate
- CAS No.
- 641569-96-2
- Chemical Name
- 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate
- Synonyms
- NILOTINIB IMPURITY 22;Nilotinib Impurity 35;Nilotinib Impurity 16(Nitrate);ethyl 3-guanidino-4-methylbenzoate;Ethyl 3-guanidino-4-methylbenzoate nitrate;Ethyl 3-Carbamimidoylamino-p-toluate Nitrate;2-Methyl-5-(ethylcarboxy)phenylguanidine nitrate;Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate;3-Carbamimidoylamino-p-toluic Acid Ethyl Ester Nitrate;Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate >
- CBNumber
- CB72128666
- Molecular Formula
- C11H16N4O5
- Formula Weight
- 284.27
- MOL File
- 641569-96-2.mol
3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate Property
- Melting point:
- 197.0 to 201.0 °C
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- color
- White to Almost white
Safety
- HS Code
- 2925.29.9000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- E1079
- Product name
- Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate
- Purity
- >97.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $36
- Updated
- 2024/03/01
- Product number
- E1079
- Product name
- Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate
- Purity
- >97.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $164
- Updated
- 2024/03/01
- Product number
- 095837
- Product name
- Ethyl 3-guanidino-4-methylbenzoate nitrate
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $213
- Updated
- 2021/12/16
- Product number
- AK102656
- Product name
- Ethyl3-guanidino-4-methylbenzoatenitrate
- Purity
- 97%
- Packaging
- 25g
- Price
- $74
- Updated
- 2021/12/16
- Product number
- 095837
- Product name
- Ethyl 3-guanidino-4-methylbenzoate nitrate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $471
- Updated
- 2021/12/16
3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate Chemical Properties,Usage,Production
Chemical Properties
3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate Appearance white to almost white powder to crystals, melting point 199 °C, storage 2-8 °C.
Uses
3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate is an organic synthetic material or pharmaceutical intermediate compound that can be used in the preparation of N-phenyl-2-pyrimidinamine derivatives and in the synthesis of nilotinib and its salts. Nilotinib is a tyrosine kinase inhibitor used for the treatment of drug-resistant chronic myelogenous leukemia (CML), and in particular, for the treatment of chronic phase and accelerated phase Philadelphia chromosome positive chronic myeloid leukemia (CML) in adult patients whose disease has progressed on or who cannot tolerate other therapies that included imatinib. Nilotinib is administrated as a hydrochloride salt in the form of capsules that are marketed in the USA and the EU under the name Tasigna?.
3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate Preparation Products And Raw materials
Raw materials
Preparation Products
3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate Suppliers
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- Country
- Germany
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- 98
- Advantage
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- Germany
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View Lastest Price from 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate manufacturers
- Product
- 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate 641569-96-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-20
- Product
- 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate 641569-96-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2018-08-13