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2-Aminobenzo[b]thiophene

Product Name
2-Aminobenzo[b]thiophene
CAS No.
4521-30-6
Chemical Name
2-Aminobenzo[b]thiophene
Synonyms
benzothiophen-2-amine;2-Aminobenzo[b]thiophene
CBNumber
CB72140424
Molecular Formula
C8H7NS
Formula Weight
149.21
MOL File
4521-30-6.mol
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2-Aminobenzo[b]thiophene Property

Melting point:
115-117 °C
Boiling point:
313.1±15.0 °C(Predicted)
Density 
1.294±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
Chloroform (Sligthly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
3.79±0.10(Predicted)
color 
Pale Red to Very Dark Brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B206875
Product name
Benzo[b]thiophen-2-amine
Packaging
250mg
Price
$470
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0391809
Product name
BENZO[B]THIOPHEN-2-AMINE
Purity
95.00%
Packaging
5MG
Price
$496.28
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140394
Product name
Benzo[b]thiophen-2-amine
Packaging
2g
Price
$615
Updated
2021/12/16
Matrix Scientific
Product number
075877
Product name
Benzo[b]thiophen-2-amine
Purity
95+%
Packaging
250mg
Price
$629
Updated
2021/12/16
Matrix Scientific
Product number
075877
Product name
Benzo[b]thiophen-2-amine
Purity
95+%
Packaging
1g
Price
$1357
Updated
2021/12/16
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2-Aminobenzo[b]thiophene Chemical Properties,Usage,Production

Synthesis

89673-36-9

4521-30-6

General procedure for the synthesis of benzo[b]thiophen-2-amine from tert-butyl benzothiophen-2-ylcarbamate: tert-butyl 1-benzothiophen-2-ylcarbamate (1.0 g, 4.01 mmol) was added to a solution of 1-benzothiophen-2-ylcarbamate in dichloromethane (DCM, 10 mL), and the reaction was stirred at room temperature for 12 hours. Upon completion of the reaction, the reaction mixture was concentrated and the resulting residue was redissolved in dichloromethane, washed sequentially with 1N sodium hydroxide solution (2 x 50 mL) and saturated saline, and the organic phase was dried with anhydrous sodium sulfate. The drier was removed by filtration and the filtrate was concentrated to give the pure benzo[b]thiophen-2-amine (0.54 g, 91% yield).LCMS (m/z): 150.0 (M + H).

References

[1] Patent: WO2006/41968, 2006, A1. Location in patent: Page/Page column 38
[2] Patent: US2007/105864, 2007, A1. Location in patent: Page/Page column 193
[3] Patent: US2007/117804, 2007, A1. Location in patent: Page/Page column 125

2-Aminobenzo[b]thiophene Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Aminobenzo[b]thiophene Suppliers

Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
Advantage
55
Shanghai Run-Biotech Co., Ltd.
Tel
021-57171705 13817537615
Fax
QQ3095748324
Email
sales@run-biotech.com
Country
China
ProdList
2337
Advantage
58
Shanghai Boyners Pharm-Tech Co., Ltd.
Tel
13817873692
Fax
021-31329586
Email
mkt@boynerspharm.com
Country
China
ProdList
1707
Advantage
55
DebyeTec.com Inc.
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18-086626237 18086626237
Fax
qq:2693528373
Email
2693528373@qq.com
Country
China
ProdList
2973
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56
Shanghai RenYue Chemical Technology Co., Ltd.
Tel
021-62219190; 18321139117
Email
316441092@qq.com
Country
China
ProdList
2905
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55
Shanghai Kahn Pharmaceutical Co., Ltd.
Tel
021-34979681; 17701870669
Fax
021-34979681
Email
41513101@qq.com
Country
China
ProdList
1785
Advantage
55
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View Lastest Price from 2-Aminobenzo[b]thiophene manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Aminobenzo[b]thiophene 4521-30-6
Price
US $25.00-11.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000KG
Release date
2024-08-12