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Rutundic acid

Product Name
Rutundic acid
CAS No.
20137-37-5
Chemical Name
Rutundic acid
Synonyms
Rutundic acid;Rotundic acid;I1exo1ic acid;Ilexolic acid A;Rotundic acid-RM;CAS20137-37-5 Rutundic acid;Rotundic acid, 10 mM in DMSO;3β,19,23-Trihydroxyurs-12-en-28-oic acid;3β,19α,23-Trihydroxyurs-12-ene-28-oic acid;(3beta,4alpha)-3,19,23-Trihydroxyurs-12-en-28-oic acid
CBNumber
CB72291900
Molecular Formula
C30H48O5
Formula Weight
488.7
MOL File
20137-37-5.mol
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Rutundic acid Property

Melting point:
272-274℃
Boiling point:
622.8±55.0 °C(Predicted)
Density 
1.19
storage temp. 
4°C, protect from light
solubility 
Soluble in DMSO and methanol;
form 
powder
pka
4.47±0.70(Predicted)
color 
White
Water Solubility 
insoluble in water
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL84256
Product name
Rotundic acid
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$403
Updated
2025/07/31
Usbiological
Product number
361870
Product name
Rotundic Acid
Packaging
10mg
Price
$439
Updated
2021/12/16
ChemScene
Product number
CS-0019536
Product name
Rotundicacid
Purity
≥99.0%
Packaging
5mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-0019536
Product name
Rotundicacid
Purity
≥99.0%
Packaging
10mg
Price
$250
Updated
2021/12/16
Biorbyt Ltd
Product number
orb105574
Product name
Rutundic acid
Purity
>98%,Standard References Grade
Packaging
20mg
Price
$569.5
Updated
2021/12/16
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Rutundic acid Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Ilex pubescens.

Uses

Rotundic acid, a triterpenoid obtained from Ilex rotunda Thunb., induces DNA damage and cell apoptosis in hepatocellular carcinoma through AKT/mTOR and MAPK Pathways. Rotundic acid possesses anti-inflammatory and cardio-protective abilities[1].

Definition

ChEBI: A natural product found in Euscaphis japonica.

IC 50

mTOR; p38 MAPK

References

[1] Roy G, et al. Rotundic Acid Induces DNA Damage and Cell Death in Hepatocellular Carcinoma Through AKT/mTOR and MAPK Pathways. Front Oncol. 2019 Jun 26;9:545. DOI:10.3389/fonc.2019.00545

Rutundic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Rutundic acid Suppliers

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View Lastest Price from Rutundic acid manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Rutundic acid 20137-37-5
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-25
Career Henan Chemical Co
Product
Rutundic acid 20137-37-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-12

20137-37-5, Rutundic acidRelated Search:

roburic acid Poricoic acid A(F) Terrestrosin D Pachymic acid Carboxyatractyloside Gastrodin talatisamine Stevioside (S)-3-(Allylsulphinyl)-L-alanine Specneuzhenide SANTALOL Sakakin RUBUSOSIDE Amentoflavone Aucubin GAMBOGIC ACID (3beta,5alpha,11alpha,12beta,14beta,17alpha)-12-(Acetyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-beta-D-allopyranosyl)-3-O-methyl-beta-D-arabinohexopyranosyl]oxy]-8,14-epoxy-11-(2-methyl-1-oxobutoxy)pregnan-20-one Betaine

  • 3β,19,23-Trihydroxyurs-12-en-28-oic acid
  • 3β,19α,23-Trihydroxyurs-12-ene-28-oic acid
  • Rotundic acid
  • Rutundic acid
  • (3beta,4alpha)-3,19,23-Trihydroxyurs-12-en-28-oic acid
  • (1R,2R,4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-1,10-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid
  • Ilexolic acid A
  • I1exo1ic acid
  • (1R,2R,4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-1,10-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylicaci
  • (1R,2R,4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-1,10-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
  • CAS20137-37-5 Rutundic acid
  • Rotundic acid-RM
  • Rotundic acid, 10 mM in DMSO
  • 20137-37-5