ChemicalBook > CAS DataBase List > KIGAMICIN C
KIGAMICIN C
- Product Name
- KIGAMICIN C
- CAS No.
- 680571-51-1
- Chemical Name
- KIGAMICIN C
- Synonyms
- KIGAMICIN C;Oxazolo[3,2-b]xantheno[4',3',2':4,5][1,3]benzodioxino[7,6-g]isoquinoline-16,19-dione, 3-[[(2S,5S,6R)-5-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1,2,3,4,8a,9,11,11a,13,14-decahydro-1,4,17,18-tetrahydroxy-11a-methyl-, (1S,3R,4S,8aR,11aR)-
- CBNumber
- CB72453298
- Molecular Formula
- C41H47NO16
- Formula Weight
- 809.81
- MOL File
- 680571-51-1.mol
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KIGAMICIN C Property
- storage temp.
- Store at -20°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form
- Yellow powder.
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 19445
- Product name
- Kigamicin C
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $303
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 19445
- Product name
- Kigamicin C
- Purity
- ≥98%
- Packaging
- 2.5mg
- Price
- $1133
- Updated
- 2024/03/01
TRC
- Product number
- K570508
- Product name
- KigamicinC
- Packaging
- 500μg
- Price
- $255
- Updated
- 2021/12/16
Usbiological
- Product number
- K1765-25
- Product name
- Kigamicin C
- Packaging
- 500ug
- Price
- $523
- Updated
- 2021/12/16
Usbiological
- Product number
- 453048
- Product name
- Kigamicin C
- Packaging
- 500μg
- Price
- $573
- Updated
- 2021/12/16
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KIGAMICIN C Chemical Properties,Usage,Production
Uses
Kigamicin C was discovered by an anti-austerity strategy, targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blockade of aPKB/Akt activation, caused by the withdrawal of nutrients. It is active in vivo against a human pancreatic cancer xenograft model. Kigamicin C also inhibits the growth of Gram positive bacteria including MRSA, but is not active against Gram negative bacteria.
Uses
Kigamicin C is a novel antibiotic antiproliferative with novel action.
KIGAMICIN C Preparation Products And Raw materials
Raw materials
Preparation Products
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KIGAMICIN C Suppliers
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KIGAMICIN C
3',4'-DIMETHOXYBIPHENYL-3-CARBALDEHYDE
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1-(2-HYDROXY-5-METHOXY-4-METHYL-PHENYL)-ETHANONE
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