KIGAMICIN C

Product Name: KIGAMICIN C
CAS No.: 680571-51-1
Chemical Name: KIGAMICIN C
Synonyms: KIGAMICIN C;Oxazolo[3,2-b]xantheno[4',3',2':4,5][1,3]benzodioxino[7,6-g]isoquinoline-16,19-dione, 3-[[(2S,5S,6R)-5-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1,2,3,4,8a,9,11,11a,13,14-decahydro-1,4,17,18-tetrahydroxy-11a-methyl-, (1S,3R,4S,8aR,11aR)-
CBNumber: CB72453298
Molecular Formula: C41H47NO16
Formula Weight: 809.81
MOL File: 680571-51-1.mol

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KIGAMICIN C Property

storage temp.: Store at -20°C
solubility: DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form: Yellow powder.

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19445
Product name: Kigamicin C
Purity: ≥98%
Packaging: 500μg
Price: $303
Updated: 2024/03/01

Cayman Chemical

Product number: 19445
Product name: Kigamicin C
Purity: ≥98%
Packaging: 2.5mg
Price: $1133
Updated: 2024/03/01

TRC

Product number: K570508
Product name: KigamicinC
Packaging: 500μg
Price: $255
Updated: 2021/12/16

Usbiological

Product number: K1765-25
Product name: Kigamicin C
Packaging: 500ug
Price: $523
Updated: 2021/12/16

Usbiological

Product number: 453048
Product name: Kigamicin C
Packaging: 500μg
Price: $573
Updated: 2021/12/16

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KIGAMICIN C Chemical Properties,Usage,Production

Uses

Kigamicin C was discovered by an anti-austerity strategy, targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blockade of aPKB/Akt activation, caused by the withdrawal of nutrients. It is active in vivo against a human pancreatic cancer xenograft model. Kigamicin C also inhibits the growth of Gram positive bacteria including MRSA, but is not active against Gram negative bacteria.

Uses

Kigamicin C is a novel antibiotic antiproliferative with novel action.

KIGAMICIN C Preparation Products And Raw materials

Raw materials

Preparation Products

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KIGAMICIN C Suppliers

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680571-51-1, KIGAMICIN CRelated Search:

21-hydroxyoligomycin A anguinomycin A Hexacyclinic acid KAZUSAMYCIN A FROM STREPTOMYCES SP. echinosporin Daunorubicin hydrochloride PD 124895 Cladospirone bisepoxide Cochliodinol,fromChaetomiumglobosum. 6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 4-(6-deoxy-alpha-galactofuranosy l)-1-hydroxy-10,12-dimethoxy-8-methyl- Maltoryzine KIGAMICIN C 3',4'-DIMETHOXYBIPHENYL-3-CARBALDEHYDE 2,5-DIHYDROXY-4'-METHYLBIPHENYL 1-(2-HYDROXY-5-METHOXY-4-METHYL-PHENYL)-ETHANONE 7-METHYL-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 4-hydroxy-5-methoxy-1,1'-biphenyl-3-carbaldehyde 8-HYDROXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE

KIGAMICIN C

Oxazolo[3,2-b]xantheno[4',3',2':4,5][1,3]benzodioxino[7,6-g]isoquinoline-16,19-dione, 3-[[(2S,5S,6R)-5-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1,2,3,4,8a,9,11,11a,13,14-decahydro-1,4,17,18-tetrahydroxy-11a-methyl-, (1S,3R,4S,8aR,11aR)-

680571-51-1

C41H47NO16