3-Fluoro-4-Bromoobenzyl Cyanide

Uses

Product Name: 3-Fluoro-4-Bromoobenzyl Cyanide
CAS No.: 499983-13-0
Chemical Name: 3-Fluoro-4-Bromoobenzyl Cyanide
Synonyms: 3-Fluoro-4-broMobenzyl cyanide;4-Bromo-3-fluorobenzyl cyanide;3-Fluoro-4-Bromoobenzyl Cyanide;4-Bromo-3-fluorophenylacetonitrile;4-Bromo-3-fluorobenzeneacetonitrile;3-Fluoro-4-bromophenyl acetonitrile;Benzeneacetonitrile, 4-bromo-3-fluoro-;2-(4-BroMo-3-fluorophenyl)acetonitrile
CBNumber: CB72485635
Molecular Formula: C8H5BrFN
Formula Weight: 214.03
MOL File: 499983-13-0.mol

More

Less

3-Fluoro-4-Bromoobenzyl Cyanide Property

Boiling point:: 279℃
Density: 1.573
Flash point:: 122℃
storage temp.: 2-8°C
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C8H5BrFN/c9-7-2-1-6(3-4-11)5-8(7)10/h1-2,5H,3H2
InChIKey: CGDCFGJXTOGEGD-UHFFFAOYSA-N
SMILES: C1(CC#N)=CC=C(Br)C(F)=C1

More

Less

Safety

RIDADR: 3439
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 2926907090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

More

Less

N-Bromosuccinimide Price

TRC

Product number: B677853
Product name: 2-(4-Bromo-3-fluorophenyl)acetonitrile
Packaging: 250mg
Price: $55
Updated: 2021/12/16

AK Scientific

Product number: J98092
Product name: 4-Bromo-3-fluorophenylacetonitrile
Packaging: 5g
Price: $60
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3637-B-X4
Product name: 4-Bromo-3-fluorophenylacetonitrile
Packaging: 1g
Price: $64
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB105504
Product name: 2-(4-bromo-3-fluorophenyl)acetonitrile
Packaging: 1g
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: J98092
Product name: 4-Bromo-3-fluorophenylacetonitrile
Packaging: 10g
Price: $100
Updated: 2021/12/16

More

Less

3-Fluoro-4-Bromoobenzyl Cyanide Chemical Properties,Usage,Production

Uses

3-Fluoro-4-bromophenylacetonitrile is a commonly used chemical intermediate, prepared by cyanidation.

Chemical Properties

Off-white powder

Synthesis

127425-73-4

773837-37-9

499983-13-0

A mixture of 3-fluoro-4-bromobenzyl bromide (27 mmol) and sodium cyanide (2.38 g, 54 mmol, 2.0 eq.) in ethanol (100 mL) was heated and reacted at 80 °C for 2 hours. Upon completion of the reaction, the mixture was concentrated to dryness under vacuum, followed by suspension of the residue in water and extraction with ethyl acetate. The organic phase was washed with brine and dried over anhydrous sodium sulfate. The solvent was removed under reduced pressure to give the crude product as a heavy oil. Purification by silica gel column chromatography (eluent gradient: 2%→12% ethyl acetate/hexane) resulted in 3-fluoro-4-bromophenylacetonitrile as white acicular crystals (1.96 g, 35% overall yield in two steps).

References

[1] Patent: WO2011/15287, 2011, A2. Location in patent: Page/Page column 13; 14
[2] Patent: US2011/39934, 2011, A1. Location in patent: Page/Page column 5
[3] Patent: EP2700643, 2014, A1. Location in patent: Paragraph 0235
[4] Patent: US2015/368278, 2015, A1. Location in patent: Paragraph 1263
[5] Patent: WO2017/98440, 2017, A1. Location in patent: Page/Page column 184

3-Fluoro-4-Bromoobenzyl Cyanide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-Fluoro-4-Bromoobenzyl Cyanide Suppliers

Canada 1 China 98 India 1 Switzerland 1 United Kingdom 3 United States 10 Global 114

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 021-31038972,31038973 17321035817
Fax: +86-21-51385350
Email: sales@harvest-chem.com
Country: China
ProdList: 2816
Advantage: 64

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 4000
Advantage: 55

Wuhan ariel chemical Co., LTD.

Tel: 18986259541
Fax: 027-87840182
Email: sales@3stc.com
Country: China
ProdList: 3764
Advantage: 58

More

Less

View Lastest Price from 3-Fluoro-4-Bromoobenzyl Cyanide manufacturers

R&D Scientific Inc.

Product: 4-Bromo-3-fluorophenylacetonitrile 499983-13-0
Price: US $500.00/g
Min. Order: 1g
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-02-12

Career Henan Chemical Co

Product: 3-Fluoro-4-Bromoobenzyl Cyanide 499983-13-0
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-17

499983-13-0, 3-Fluoro-4-Bromoobenzyl CyanideRelated Search:

α-Bromo-2,3,4,5,6-pentafluorotoluene 4-Fluorobenzyl bromide 1-BroMoheptadecafluorooctane 4-BROMO-3-FLUOROPHENYLACETIC ACID 4-Bromo-3-fluorobenzaldehyde

3-Fluoro-4-Bromoobenzyl Cyanide

3-Fluoro-4-bromophenyl acetonitrile

4-Bromo-3-fluorobenzeneacetonitrile

4-Bromo-3-fluorophenylacetonitrile

3-Fluoro-4-broMobenzyl cyanide

2-(4-BroMo-3-fluorophenyl)acetonitrile

4-Bromo-3-fluorobenzyl cyanide

Benzeneacetonitrile, 4-bromo-3-fluoro-

499983-13-0