ChemicalBook > CAS DataBase List > 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
Physical Form- Product Name
- 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
- CAS No.
- 1180132-17-5
- Chemical Name
- 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
- Synonyms
- Abemaciclib Impurity 4;LY2835219 Intermediate 1;5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridin;5-((4-Ethylpiperazin-1-y)methyDpyridin-2-amine;5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-amin;-((4-Ethylpiperazin-1-yl)Methyl)pyridin-2-aMine;5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine;5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinamine;2-Amino-5-[(4-ethyl-1-piperazinyl)methyl]pyridine;5-((4-ethylpiperazin-1-yl)methyl)pyridine-2-amine
- CBNumber
- CB72500105
- Molecular Formula
- C12H20N4
- Formula Weight
- 220.31
- MOL File
- 1180132-17-5.mol
More
Less
5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine Property
- Boiling point:
- 362℃
- Density
- 1.101
- Flash point:
- 173℃
- storage temp.
- 2-8°C(protect from light)
- pka
- 7.71±0.10(Predicted)
- Appearance
- White to yellow Solid
- InChI
- InChI=1S/C12H20N4/c1-2-15-5-7-16(8-6-15)10-11-3-4-12(13)14-9-11/h3-4,9H,2,5-8,10H2,1H3,(H2,13,14)
- InChIKey
- MNJBMPQTXVZMFZ-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=C(CN2CCN(CC)CC2)C=C1
More
Less
Safety
- HS Code
- 2933599590
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P330Rinse mouth.
P501Dispose of contents/container to..…
More
Less
N-Bromosuccinimide Price
TRC
- Product number
- E926858
- Product name
- 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
TRC
- Product number
- E926858
- Product name
- 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
AK Scientific
- Product number
- 2951AA
- Product name
- 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
- Packaging
- 5g
- Price
- $195
- Updated
- 2021/12/16
Apolloscientific
- Product number
- OR471684
- Product name
- 2-Amino-5-[(4-ethyl-1-piperazinyl)methyl]pyridine
- Packaging
- 5g
- Price
- $226
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 3H30-1-KV
- Product name
- 2-Amino-5-[(4-ethyl-1-piperazinyl)methyl]pyridine
- Purity
- 95%
- Packaging
- 5G
- Price
- $268
- Updated
- 2021/12/16
More
Less
5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine Chemical Properties,Usage,Production
Physical Form
Solid
Uses
5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine is a useful research chemical.
Flammability and Explosibility
Not classified
Synthesis
121-44-8
156973-09-0
1180132-17-5
To a 500 mL four-necked round-bottomed flask equipped with a thermometer and condenser tube were added 100 g of 1,2-dichloroethane, 12.5 g (0.1 mol) of 5-(aminomethyl)pyridin-2-amine (IV) and 30.0 g of potassium carbonate. A solution consisting of 25.0 g (0.15 mol) N,N-diethylethylamine and 20 g of 1,2-dichloroethane was added slowly and dropwise over a period of about 2 hours at 30 to 35 °C. The reaction temperature was maintained at 30~35°C and stirring was continued for 6 hours. After completion of the reaction, it was cooled to 20~25°C and layered. The aqueous layer was extracted twice with 1,2-dichloroethane at 20 g. The organic phases were combined and the 1,2-dichloroethane was removed by distillation. To the residue was added 75 g of methyl tert-butyl ether and 0.5 g of activated charcoal and stirred at 80~82°C for 1 hr. After hot filtration, the filtrate was cooled to 0~5°C for crystallization, filtered and dried to afford 18.2 g of 5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-amine as a white solid in 82.7% yield and 99.3% purity of the liquid phase.
References
[1] Patent: CN107337634, 2017, A. Location in patent: Paragraph 0040; 0053; 0054; 0057; 0058; 0061; 0062
5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine Suppliers
- Tel
- 19862069201
- 3844950497@qq.com
- Country
- China
- ProdList
- 290
- Advantage
- 55
- Tel
- 0571-89081561; 10006559855
- Fax
- 0571 89081561
- info@cheminspire.com
- Country
- China
- ProdList
- 412
- Advantage
- 58
- Tel
- 0571-86828652 18857119830
- Fax
- 0571-83522824
- sales@chemtrue-bio.com
- Country
- China
- ProdList
- 252
- Advantage
- 58
- Tel
- 0512-67903504 13814824891
- Fax
- QQ604360797
- 604360797@qq.com
- Country
- China
- ProdList
- 399
- Advantage
- 58
- Tel
- 0534-2152677 18660163165
- sale@inyelchem.com
- Country
- China
- ProdList
- 264
- Advantage
- 58
- Tel
- 0531-82371986 15269101859
- Fax
- 0531-82375893
- 3276840968@qq.com
- Country
- China
- ProdList
- 1604
- Advantage
- 58
- Tel
- 18632776803
- 355803330@qq.com
- Country
- China
- ProdList
- 630
- Advantage
- 58
- Tel
- 0317-5106596 15533709196
- 1154424302@qq.com
- Country
- China
- ProdList
- 2262
- Advantage
- 58
- Tel
- 025-58741518 13327700685
- sales@vcarepharmatech.com
- Country
- China
- ProdList
- 496
- Advantage
- 58
- Tel
- Fax
- 86-21-57758967
- sales@boylechem.com
- Country
- China
- ProdList
- 2922
- Advantage
- 55
- Tel
- 025-86918202 4000255188
- Fax
- 86-025-86918232
- sales@pharmablock.com
- Country
- China
- ProdList
- 5000
- Advantage
- 55
- Tel
- 18515581800 18501085097
- Fax
- 010-89508210
- sales.bj@hwrkchemical.com
- Country
- China
- ProdList
- 9400
- Advantage
- 55
- Tel
- 28-83379370 13880556291
- Fax
- 028-87747383
- tcy@tcypharm.com
- Country
- China
- ProdList
- 510
- Advantage
- 57
- Tel
- 13526569071
- sales@leadmedpharm.com
- Country
- China
- ProdList
- 7892
- Advantage
- 64
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 021-34975603-808 18721111801
- Fax
- +86-21-34975602-805
- sales@bocpharma.com
- Country
- China
- ProdList
- 1009
- Advantage
- 64
- Tel
- 027-88320699
- Fax
- 027-88320962
- tycshyy@126.com
- Country
- China
- ProdList
- 297
- Advantage
- 66
- Tel
- 021-58950125
- Fax
- (86) 21-58955996
- info@chemexpress.com
- Country
- China
- ProdList
- 7552
- Advantage
- 61
- Tel
- 13661494087 18964793018
- Fax
- 86-021-51821718 QQ：2427604606
- sales@mof-chemicals.com
- Country
- China
- ProdList
- 293
- Advantage
- 55
- Tel
- 0551-66399836 18955197623
- sales@enlipharma.com
- Country
- China
- ProdList
- 1876
- Advantage
- 55
- Tel
- 0512-62857507
- Fax
- +86-512-62857507
- sales@sinorarechem.com
- Country
- China
- ProdList
- 991
- Advantage
- 58
- Tel
- 0523-86818997 18652728585
- sales@allyrise.com
- Country
- China
- ProdList
- 2966
- Advantage
- 60
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 13816752554
- 1745533547@qq.com
- Country
- China
- ProdList
- 129
- Advantage
- 58
- Tel
- 023-89130144 18523560356
- Fax
- 023-67534737
- zhyong1011@163.com
- Country
- China
- ProdList
- 290
- Advantage
- 58
- Tel
- 0512-62968256 18550502935
- Fax
- 0512-62968256
- export@laingbiotec.com
- Country
- China
- ProdList
- 981
- Advantage
- 58
- Tel
- 027-87465837 19945049750
- Fax
- 027-8777-2287
- sales@finetechnology-ind.com
- Country
- China
- ProdList
- 9637
- Advantage
- 58
- Tel
- 18112588827
- sales4@sepharm.com.cn
- Country
- China
- ProdList
- 285
- Advantage
- 60
- Tel
- 0531-68652053 15863796298;
- 2310993908@qq.com
- Country
- China
- ProdList
- 2437
- Advantage
- 58
- Tel
- 86(21)68097365
- Fax
- 86(21)33321566
- sales@anpharma.net
- Country
- China
- ProdList
- 4891
- Advantage
- 55
- Tel
- +86-18512541987
- Fax
- 0555-5963572
- hll@farmasino.com
- Country
- China
- ProdList
- 241
- Advantage
- 60
- Tel
- 13585175604 13057662806
- Fax
- +86-25-52261140
- sales@chicopharm.com
- Country
- China
- ProdList
- 500
- Advantage
- 65
- Tel
- 18068075658
- Fax
- -
- sales@chempioneer.com
- Country
- China
- ProdList
- 1811
- Advantage
- 58
- Tel
- 0512-63009836 18994340901
- Fax
- 0512-63006936
- helen@struchem.com
- Country
- China
- ProdList
- 3981
- Advantage
- 60
- Tel
- 21-619849051-1 18521059765
- synchempharma@aliyun.com
- Country
- China
- ProdList
- 6468
- Advantage
- 55
- Tel
- 0514-80939770 13773367191
- Fax
- 0514-82664689
- yzqyyykj@163.com
- Country
- China
- ProdList
- 252
- Advantage
- 55
- Tel
- 021-38751876 15000076078
- Fax
- 021-50275764
- Info@rochipharma.com
- Country
- China
- ProdList
- 611
- Advantage
- 55
- Tel
- 18915409046
- Fax
- 0510-86566870
- 1102409417@qq.com
- Country
- China
- ProdList
- 268
- Advantage
- 55
- Tel
- +86-400-851-9921
- Fax
- +86-10-82826195
- sales@pharmacodia.com
- Country
- China
- ProdList
- 2317
- Advantage
- 55
- Tel
- 027-87614241 3310618156
- Fax
- -
- 3310618156@qq.com
- Country
- China
- ProdList
- 62
- Advantage
- 50
- Tel
- 025-83453382-8005
- Fax
- 025-83453382
- sale@parabiochem.com
- Country
- China
- ProdList
- 9595
- Advantage
- 55
- Tel
- 23-67950001 13883380852
- Fax
- 023-68265899
- cqhfyy@foxmail.com
- Country
- China
- ProdList
- 72
- Advantage
- 55
- Tel
- 0317-5296180 15533709196
- Fax
- 0317-5106596
- sale@enkepharma.com
- Country
- China
- ProdList
- 2267
- Advantage
- 55
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8000
- Advantage
- 62
- Tel
- 028-83379370 13880556291
- Fax
- 028-87747383
- tcy@tcypharm.com
- Country
- China
- ProdList
- 7218
- Advantage
- 58
- Tel
- Fax
- -
- 13006575422@163.com
- Country
- China
- ProdList
- 6355
- Advantage
- 58
- Tel
- 18601958187
- Fax
- 18601958187
- 247340078@qq.com
- Country
- China
- ProdList
- 144
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 15374522761
- Fax
- QQ:2853117752
- 3003392093@yongstandards.com
- Country
- China
- ProdList
- 10000
- Advantage
- 55
- Tel
- 18800375331
- Fax
- 021-50908862
- kangmansales@163.com
- Country
- China
- ProdList
- 7570
- Advantage
- 55
More
Less
View Lastest Price from 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine manufacturers
Jinan Ruitong Biotech Co., Ltd.
- Product
- 5-((4-ethylpiperazin-1-yl)methyl)pyridine-2-amine 1180132-17-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1
- Release date
- 2025-08-28
Shaanxi Dideu New Materials Co. Ltd
- Product
- 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine 1180132-17-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-06-10
Yangzhou Qinyuan Pharmatech Co.,ltd
- Product
- 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine 1180132-17-5
- Price
- US $10.00/g
- Min. Order
- 10g
- Purity
- 0.99
- Supply Ability
- 1ton
- Release date
- 2025-05-14
1180132-17-5, 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amineRelated Search:
1H-BenziMidazole, 4-fluoro-2-Methyl-1-(1-Methylethyl)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole
2-bromo-8-fluoro-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one
PF-01367338
4-(8-fluoro-6-oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)benzaldehyde
1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)-