6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine

Product Name: 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
CAS No.: 867017-68-3
Chemical Name: 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
Synonyms: BAY-549;TC-S 7001;Azaindole 1;Rho Kinase Inhibitors;TC-S 7001(Azaindole 1);RHO-KINASE INHIBITOR;RHO KINASE INHIBITOR;RHO-KINASE INHIBITOR; RHO KINASE INHIBITOR; ROCK;6-CHLORO-N4-[3,5-DIFLUORO-4-[(3-METHYL-1H-PYRROLO[2,3-B]PYRIDIN-4-YL)OXY]PHENYL]PYRIMIDIN-2,4-DIAMINE;6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine;6-Chloro-N4-(3,5-difluoro-4-((3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)pyrimidine-2,4-diamine
CBNumber: CB72510092
Molecular Formula: C18H13ClF2N6O
Formula Weight: 402.79
MOL File: 867017-68-3.mol

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6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine Property

Density: 1.61
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: DMSO: Soluble; Ethanol: Soluble
form: A solid
pka: 13.56±0.40(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19129
Product name: TC-S 7001
Packaging: 500μg
Price: $117
Updated: 2024/03/01

Cayman Chemical

Product number: 19129
Product name: TC-S 7001
Packaging: 1mg
Price: $186
Updated: 2024/03/01

Cayman Chemical

Product number: 19129
Product name: TC-S 7001
Packaging: 5mg
Price: $521
Updated: 2024/03/01

Tocris

Product number: 4961
Product name: TC-S7001
Purity: ≥98%(HPLC)
Packaging: 1
Price: $215
Updated: 2021/12/16

Usbiological

Product number: 466890
Product name: TC-S 7001
Packaging: 1mg
Price: $460
Updated: 2021/12/16

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6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine Chemical Properties,Usage,Production

Uses

TC-S 7001 is a novel potent and highly selective azaindole-based inhibitor of Rho-kinase (ROCK). It exhibits long-acting vasodilator activity and decreases pulmonary and systemic arterial pressure in rats.

storage

Store at -20°C

6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine Suppliers

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867017-68-3, 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamineRelated Search:

5-Chloro-2,3-difluoropyridine Dichlorodifluoromethane 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-[4-(1-methylpropyl)phenyl]acetamide

6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine

Rho Kinase Inhibitors

6-CHLORO-N4-[3,5-DIFLUORO-4-[(3-METHYL-1H-PYRROLO[2,3-B]PYRIDIN-4-YL)OXY]PHENYL]PYRIMIDIN-2,4-DIAMINE

TC-S 7001

Azaindole 1

RHO-KINASE INHIBITOR;RHO KINASE INHIBITOR

RHO-KINASE INHIBITOR; RHO KINASE INHIBITOR; ROCK

2,4-Pyrimidinediamine, 6-chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-

6-chloro-4-N-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]pyrimidine-2,4-diamine

6-Chloro-N4-(3,5-difluoro-4-((3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)pyrimidine-2,4-diamine

inhibit,Rho-kinase,Rho-associated protein kinase,Azaindole-1,ROCKIN2,Rho-associated kinase,Inhibitor,ROCK,ROCK IN 2,Azaindole1,ROK

BAY-549

TC-S 7001(Azaindole 1)

6-Chloro-N4-(3,5-difluoro-4-((3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)pyrimidine-2,4-diamine , BAY-549

867017-68-3

C18H13ClF2N6O

10mg/4780