5-Chloro-2,3-difluoropyridine

Product Name: 5-Chloro-2,3-difluoropyridine
CAS No.: 89402-43-7
Chemical Name: 5-Chloro-2,3-difluoropyridine
Synonyms: 2,3-DIFLUORO-5-CHLOROPYRIDINE;2,3-Difulor-5-Chloropyridine;2,3-Difluoro-5-Chloro;2,3-DIFLUORO-5-CHLOROPYRIDIN;2,3-Difuoro-5-chloropyridine;2,3-fluoro-5-chloro pyridine;5-CHLORO-2,3-DIFLUOROPYRIDINE;5-Chloro-2,3 difluro pyridine;5-Chloro-2,3-Difluoropyridine96%;5-Chloro-2,3-difluoropyridine98%
CBNumber: CB8438870
Molecular Formula: C5H2ClF2N
Formula Weight: 149.53
MOL File: 89402-43-7.mol

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5-Chloro-2,3-difluoropyridine Property

Melting point:: 47-49 C
Boiling point:: 135°C
Density: 1.442 g/mL at 25 °C
refractive index: 1.4738
Flash point:: 135°C
storage temp.: 2-8°C
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka: -5.14±0.20(Predicted)
form: Oil
color: Clear Colourless
BRN: 4177319
InChI: InChI=1S/C5H2ClF2N/c6-3-1-4(7)5(8)9-2-3/h1-2H
InChIKey: PERMDYZFNQIKBL-UHFFFAOYSA-N
SMILES: C1(F)=NC=C(Cl)C=C1F
CAS DataBase Reference: 89402-43-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-52/53-10-36/37/38-20/21/22
Safety Statements: 23-36-61-26
RIDADR: 2810
WGK Germany: 3
Hazard Note: Harmful
HazardClass: IRRITANT
HazardClass: 3
PackingGroup: III
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 720208
Product name: 2,3-Difluoro-5-chloropyridine
Purity: 95%
Packaging: 5g
Price: $17.1
Updated: 2023/06/20

TCI Chemical

Product number: C2113
Product name: 5-Chloro-2,3-difluoropyridine
Purity: >93.0%(GC)
Packaging: 5g
Price: $19
Updated: 2025/07/31

TCI Chemical

Product number: C2113
Product name: 5-Chloro-2,3-difluoropyridine
Purity: >93.0%(GC)
Packaging: 25g
Price: $60
Updated: 2025/07/31

TRC

Product number: C365385
Product name: 5-Chloro-2,3-difluoropyridine
Packaging: 25g
Price: $140
Updated: 2021/12/16

TRC

Product number: C365385
Product name: 5-Chloro-2,3-difluoropyridine
Packaging: 250g
Price: $1110
Updated: 2021/12/16

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5-Chloro-2,3-difluoropyridine Chemical Properties,Usage,Production

Uses

5-Chloro-2,3-difluoropyridine is a 2,3,5-trihalopyridine used in the preparation of the herbicides and pesticides such as chodinafop-propargyl.

Synthesis

16063-70-0

89402-43-7

General procedure for the synthesis of 2,3-difluoro-5-chloropyridine from 2,3,5-trichloropyridine: First, 400 g of cyclobutanesulfone and 400 g of dimethylsulfoxide were added to a 1000 mL flask, and dehydrated to a moisture content of less than 0.05% at 200 °C under 0.05 MPa (negative pressure). Subsequently, 96 g (1.66 mol) of potassium fluoride, 120 g (0.67 mol) of 2,3,5-trichloropyridine, 2 g of 18-crown ether, and 3 g of potassium carbonate were added to the reaction flask at 120 °C and heated to 200 °C for about 3 hours. After completion of the reaction, the product was collected to give 95 g (0.51 mol) of 2,3-difluoro-5-chloropyridine in 90% yield. The purity of the product was 96.8% as determined by gas chromatography.

References

[1] Patent: CN106008329, 2016, A. Location in patent: Paragraph 0008; 0009
[2] Synthetic Communications, 2004, vol. 34, # 23, p. 4301 - 4311
[3] Patent: US33478, 1990, E1
[4] Patent: US4565568, 1986, A
[5] Patent: US4678509, 1987, A

5-Chloro-2,3-difluoropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Chloro-2,3-difluoropyridine Suppliers

Americas 1 Canada 1 China 376 Europe 2 Germany 6 India 16 Italy 1 Japan 1 Jordan 1 United Kingdom 14 United States 39 Global 458

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Energy Chemical

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Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
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View Lastest Price from 5-Chloro-2,3-difluoropyridine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-Chloro-2,3-difluoropyridine 89402-43-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-14

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 5-Chloro-2,3-difluoropyridine 89402-43-7
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2024-04-24

Hubei Lidu New Material Technology Co., Ltd

Product: 5-Chloro-2,3-difluoropyridine 89402-43-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 20tons
Release date: 2024-10-30

89402-43-7, 5-Chloro-2,3-difluoropyridineRelated Search:

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2,3-DIFLUORO-5-CHLOROPYRIDIN

2,3-DIFLUORO-5-CHLOROPYRIDINE

5-CHLORO-2,3-DIFLUOROPYRIDINE

5-Chloro-2,3-Difluoropyridine96%

2,3-Difluoro-5-Chloro

intermediate for Clodinafop-propargyl

2,3-Difulor-5-Chloropyridine

5-Chloro-2,3-difluoropyridine 98%

5-Chloro-2,3-difluoropyridine98%

5-Chloro-2,3 difluro pyridine

2,3-Difuoro-5-chloropyridine

2,3-fluoro-5-chloro pyridine

5-Chloro-2,3-difluoropyridine,97%

5-Chloro-2,3-difluoropyridine &gt

Pyridine, 5-chloro-2,3-difluoro-

5-Chloro-2,3-difluoropyridine ISO 9001：2015 REACH

2,3-Difluoro-5-chloro pyridine (CDFP)

2,3 Difluoro 5-chloro pyridine, 97%+

high quality 2,3-Difluoro-5-chloropyridine

5-Chloro-2,3-difluoropyridine（CDFP）

89402-43-7

89042-43-7

84902-43-7

C5H2CIF2N

C5H2NClF2

C5H2ClF2N

Fluorine series

alkyl Fluorine| alkyl chloride

Chloropyridines

Fluoropyridines

Halopyridines

blocks

FluoroCompounds

Pyridines

Pyridine

bc0001

89402-43-7

OLED