5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone

Product Name: 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone
CAS No.: 173140-90-4
Chemical Name: 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone
Synonyms: (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one;BNKY004-IM01;8-benzoxy-5-(R)-oxiranyl-1H-quinolin-2-one;5-(2R) -2-epoxyl-8-benzoxy-2 (1H) -quinolone;5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone;(R)-5-(2-oxiranyl)-8-benzyloxy-2(1H)-quinolinone;2 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone;8-(Benzyloxy)-5-[(2R)-oxiran-2-yl]quinolin-2(1H)-one;2(1H)-Quinolinone, 5-(2R)-oxiranyl-8-(phenylmethoxy)-;5-(2R)-2-Oxiranyl-8-(phenylmethoxy)-2(1H)-quinolinone
CBNumber: CB72516579
Molecular Formula: C18H15NO3
Formula Weight: 293.32
MOL File: 173140-90-4.mol

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5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Property

Melting point:: 155 - 157°C
Boiling point:: 556.0±50.0 °C(Predicted)
Density: 1.298
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 10.92±0.70(Predicted)
form: Solid
color: White to Pale Yellow
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B194026
Product name: (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B194026
Product name: (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one
Packaging: 100mg
Price: $195
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0032983
Product name: (R)-8-(BENZYLOXY)-5-(OXIRAN-2-YL)QUINOLIN-2(1H)-ONE
Purity: 95.00%
Packaging: 25MG
Price: $226.8
Updated: 2021/12/16

Oakwood

Product number: 212988
Product name: (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one
Purity: 95+%
Packaging: 1g
Price: $420
Updated: 2021/12/16

AK Scientific

Product number: J11352
Product name: IndacaterolImpurity5
Packaging: 25mg
Price: $45
Updated: 2021/12/16

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5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Chemical Properties,Usage,Production

Uses

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone is used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

A 5 liter flask equipped with a mechanical stirrer, thermometer, and refluxing condenser was charged with 8-benzyloxy-5-[(R)-(2-bromo-1-hydroxyethyl)]-carbostyriI (70gms/0.187 moles), potassium carbonate (74 gmsl 0.536 moles), acetone (3.5 liters) and water (35 ml). The resulting slurry 'was heated to reflux and maintained for 2% hours. After completion of reaction, the hot mass was filtered on hylo bed to remove inorganics. The residue was slurried in dichloromethane (200 ml) and filtered on hyflo bed. The filtrates were combined together and concentrated under vacuum completely. The residue was dissolved. in dichloromethane (500ml) and filtered on hyflo bed to remove traces of insolubles and washed with dichloromethane(100 ml). The clear filtrate was distilled completely to obtain residue. The residue was charged with methanol (70 ml), stirred and heated to 50??C for 30 minutes. The slurry obtained was cooled to 25-30??C,chilled to 0- 5??C, stirred for 1 hour. The resulting solid was isolated by filtration, washed with methanol (30ml), followed by diisopropylether (100ml) and dried under vacuum at 60-65 ??C for 10-12 hours to yield 40-41 gms of 8-benzyloxy- 5-(R)-oxiranylcarbostyril.

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Suppliers

China 170 India 3 United States 3 Global 176

Standardpharm Co. Ltd.

Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Country: United States
ProdList: 14332
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81215950 4000-868-328
Email: customer@uwalab.com
Country: United States
ProdList: 10404
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

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View Lastest Price from 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd

Product: 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone 173140-90-4
Price: US $65.00-650.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-06

Henan Aochuang Chemical Co.,Ltd.

Product: 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone 173140-90-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Career Henan Chemical Co

Product: 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone 173140-90-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1000KG
Release date: 2019-09-04

173140-90-4, 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinoneRelated Search:

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(R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one

2(1H)-Quinolinone, 5-(2R)-oxiranyl-8-(phenylmethoxy)-

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone

Indacaterol interMediate :2 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone

8-(Benzyloxy)-5-[(2R)-oxiran-2-yl]quinolin-2(1H)-one

2 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone

8-benzoxy-5-(R)-oxiranyl-1H-quinolin-2-one

(R)-5-(2-oxiranyl)-8-benzyloxy-2(1H)-quinolinone

BNKY004-IM01

5-[(2R)-oxiran-2-yl]-8-phenylmethoxy-1H-quinolin-2-one

2(1H)-Quinolinone, 5-(2R)-2-oxiranyl-8-(phenylmethoxy)-

8-(benzyloxy)-5-((1R)-2-((5-ethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-one fumarate

(R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one( Indacaterol Impurity 5)

5-(2R)-2-Oxiranyl-8-(phenylmethoxy)-2(1H)-quinolinone

5- (2R) -2-epoxyethanyl-8-benzyloxy-2 (1H) - quinolone

5-(2R) -2-epoxyl-8-benzoxy-2 (1H) -quinolone

173140-90-4