Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid
- Product Name
- Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid
- CAS No.
- 756526-00-8
- Chemical Name
- Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid
- Synonyms
- CBZ-NH-PEG4-COOH;CBZ-NH-PEG4-acid;CBZ-AMINO-PEG4-ACID;Cbz-NH-PEG4-C2-acid;Cbz-amido-PEG4-acid;Z-NH-PEG4-CH2CH2COOH;Cbz-N-amido-PEG4-acid;CBZ-N-AMIDO-PEG4-COOH;CBZ-NH-PEG4-CH2CH2COOH;CBZ-NH-PEG?-CH?CH?COOH
- CBNumber
- CB72547010
- Molecular Formula
- C19H29NO8
- Formula Weight
- 399.44
- MOL File
- 756526-00-8.mol
Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid Property
- Boiling point:
- 571.2±50.0 °C(Predicted)
- Density
- 1.188±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 4.28±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 10268
- Product name
- CBZ-N-amido-dPEG??-acid
- Packaging
- 100mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- 10268
- Product name
- CBZ-N-amido-dPEG??-acid
- Packaging
- 1000mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- AS104151
- Product name
- CbzNH-PEG4-CH2CH2COOH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $305
- Updated
- 2021/12/16
- Product number
- 280307
- Product name
- Z-NH-PEG4-CH2CH2COOH
- Purity
- >=95%
- Packaging
- 1g
- Price
- $306
- Updated
- 2021/12/16
- Product number
- PEG1495
- Product name
- Z-NH-dPEG(4)-COOH
- Packaging
- 100mg
- Price
- $310.5
- Updated
- 2021/12/16
Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid Chemical Properties,Usage,Production
Description
Cbz-N-amido-PEG4-acid is a PEG linker containing a CBZ-protected amino group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected by acidic conditions.
Uses
Cbz-NH-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid manufacturers
- Product
- CBZ-NH-PEG4-CH2CH2COOH 756526-00-8
- Price
- US $613.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-24
- Product
- 3-oxo-1-phenyl-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid 756526-00-8
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12