ChemicalBook > CAS DataBase List > Isoescin IB
Isoescin IB
Chemical Properties Pharmacological Action Escin Ia & Isoescin Ib- Product Name
- Isoescin IB
- CAS No.
- 219944-46-4
- Chemical Name
- Isoescin IB
- Synonyms
- Aescin D;Escin IVb;Isoescin Ib;Isoescin IB(Isoaescin IB);Escin Impurity 4（Isoescin IB）;Aescin D，Isoescin Ib,Escin ivb;Escin,inhibit,Inhibitor,Escin IB,Isoescin IB;β-D-Glucopyranosiduronic acid, (3β,4β,16α,21β,22α)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-;(3beta,4beta,16alpha,21beta,22alpha)-28-(Acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-beta-D-glucopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-4)]-beta-D-glucopyranosiduronic acid
- CBNumber
- CB72554315
- Molecular Formula
- C55H86O24
- Formula Weight
- 1131.26
- MOL File
- 219944-46-4.mol
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Isoescin IB Property
- Boiling point:
- 1148.1±65.0 °C(Predicted)
- Density
- 1.46
- solubility
- Soluble in methanol;
- pka
- 2.63±0.70(Predicted)
- form
- powder
- color
- White
- Water Solubility
- slightly soluble in water
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- PHL83863
- Product name
- Isoescin IB
- Purity
- phyproof? Reference Substance
- Packaging
- 10MG
- Price
- $709
- Updated
- 2024/03/01
Usbiological
- Product number
- 300477
- Product name
- Isoescin IB
- Packaging
- 5mg
- Price
- $490
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb259321
- Product name
- Isoescin IB
- Purity
- 95%
- Packaging
- 10mg
- Price
- $552.5
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FI145247
- Product name
- Isoescin IB
- Packaging
- 2mg
- Price
- $98.76
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FI145247
- Product name
- Isoescin IB
- Packaging
- 5mg
- Price
- $197.5
- Updated
- 2021/12/16
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Isoescin IB Chemical Properties,Usage,Production
Chemical Properties
The saponins found in escin exist in two forms, β-escin and α-escin, which can be distinguished by melting point, hemolytic index, specific rotation and solubility in water. β-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts.
Pharmacological Action
Escin exhibits remarkable anti-inflammatory, anti-edematous and vasoprotective properties in a dose-dependent manner which are quite evident at 10-6–10-7 M. Escin has been traditionally used to treat conditions such as chronic venous insufficiency, hemorrhoids, inflammation and cerebral ischemic damage.
Escin Ia & Isoescin Ib
As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity. Similar to isoescin Ia is the isomer of escin Ia, Isoescin Ib is an isomer of escin Ib. Both of them were found to be isomerizable in vitro. Escin Ib and isoescin Ib exhibits stronger pharmacological activity than escin Ia and isoescin Ia. As the result, pharmacokinetics study of them would be helpful for improving the practice of escin application.
Isoescin IB Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Isoescin IB manufacturers
Career Henan Chemical Co
- Product
- Aescin D 219944-46-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 1000kg
- Release date
- 2018-12-25
219944-46-4, Isoescin IBRelated Search:
Escin
escin IIa
GYPENOSIDE-XVII
Gypenoside XLVI
AESCIN IB(SH)
Escin, monosodium salt
salviaflaside
Isoescin Ie
Isoastragaloside IV
Isoginsenoside Rh3
isocucurbitacin B
Ginsenoside Rg3
Notoginsenoside R1
Ginsengrootextract
AESCIN IA(SH)
(3beta,4beta,16alpha,21beta,22alpha)-28-(Acetyloxy)-16,22,23-trihydroxy-21-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-beta-D-glucopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-4)]-beta-D-glucopyranosiduronic acid
Escin Ie
ESCIN IIB