cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester

Product Name: cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester
CAS No.: 146231-54-1
Chemical Name: cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester
Synonyms: tert-butyl (3aR,6aS)-5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate;cis-tert-Butyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate;2-Boc-5-oxo-hexahydrocyclopenta[c]pyrrole;cis-2-Boc-5-oxohexahydrocyclopenta[c]pyrrole;(3aR,6aS)-2-Boc-5-oxohexahydrocyclopenta[c]pyrrole;tert-Butyl 5-oxo-octahydrocyclopenta-[c]pyrrole-2-carboxylate;tert-butyl cis-5-oxo-octahydrocyclopenta[c]pyrrole-2-carboxylate;cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester;(3aR,6aS)-tert-Butyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 95+%;tert-butyl cis-5-oxo-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrole-2-carboxylate
CBNumber: CB72597510
Molecular Formula: C12H19NO3
Formula Weight: 225.28
MOL File: 146231-54-1.mol

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cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester Property

Melting point:: 70-71 °C
Boiling point:: 325.8±35.0 °C(Predicted)
Density: 1.139±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: -0.82±0.20(Predicted)
form: solid
color: White to yellow
InChI: InChI=1/C12H19NO3/c1-12(2,3)16-11(15)13-6-8-4-10(14)5-9(8)7-13/h8-9H,4-7H2,1-3H3/t8-,9+
InChIKey: GGNDIMLSSMWKDR-DTORHVGONA-N
SMILES: C(N1C[C@]2([H])CC(C[C@]2([H])C1)=O)(=O)OC(C)(C)C |&1:3,8,r|

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-W005946
Product name: cis-tert-Butyl5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
Purity: 99.48%
Packaging: 1g
Price: $40
Updated: 2021/12/16

Apolloscientific

Product number: OR302643
Product name: (3aR,6aS)-tert-Butyl5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
Purity: 95+%
Packaging: 1g
Price: $103
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H51-1-4G
Product name: (3aR,6aS)-tert-Butyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
Packaging: 1g
Price: $114
Updated: 2021/12/16

ChemScene

Product number: CS-W005946
Product name: cis-tert-Butyl5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
Purity: 99.48%
Packaging: 5g
Price: $126
Updated: 2021/12/16

ChemScene

Product number: CS-W005946
Product name: cis-tert-Butyl5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
Purity: 99.48%
Packaging: 10g
Price: $240
Updated: 2021/12/16

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cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester Chemical Properties,Usage,Production

Synthesis

24424-99-5

96896-09-2

146231-54-1

Cis-hexahydrocyclopentadieno[c]pyrrol-5(1H)-one (2.0 g, 16 mmol) was used as starting material and dissolved in dichloromethane (50 mL). Subsequently, di-tert-butyl dicarbonate (5.2 g, 24 mmol), triethylamine (3.2 g, 32 mmol) and 4-dimethylaminopyridine (195 mg, 1.6 mmol) were added to the solution. The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, it was quenched by adding water (100 mL) and the aqueous and organic phases were separated. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated to give the crude product. The crude product was purified by silica gel column chromatography (eluent ratio of petroleum ether:ethyl acetate=10:1) to finally obtain tert-butyl cis-5-oxooctahydrocyclopenta[c]pyrrole-2(1H)-carboxylate (3.4 g, 94.4% yield).

References

[1] Patent: US2017/112833, 2017, A1. Location in patent: Paragraph 0550-0551

cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester Suppliers

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View Lastest Price from cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester manufacturers

Career Henan Chemical Co

Product: cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester 146231-54-1
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-08-07

146231-54-1, cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl esterRelated Search:

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146231-54-1