N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINE

Product Name: N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINE
CAS No.: 23126-82-1
Chemical Name: N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINE
Synonyms: AKOS BBS-00003135;6-Chloro-N-methyl-5-nitro-4-pyrimidinamine;N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINE;4-Pyrimidinamine, 6-chloro-N-methyl-5-nitro-
CBNumber: CB7260333
Molecular Formula: C5H5ClN4O2
Formula Weight: 188.57
MOL File: 23126-82-1.mol

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N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINE Property

Melting point:: 134 °C
Boiling point:: 374.9±42.0 °C(Predicted)
Density: 1.582±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: -0.74±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C429353
Product name: 6-Chloro-N-methyl-5-nitro-4-pyrimidinamine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC156281
Product name: 6-Chloro-N-methyl-5-nitro-4-pyrimidinamine
Packaging: 250mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC156281
Product name: 6-Chloro-N-methyl-5-nitro-4-pyrimidinamine
Packaging: 500mg
Price: $150
Updated: 2021/12/16

Matrix Scientific

Product number: 072587
Product name: 6-Chloro-N-methyl-5-nitro-4-pyrimidinamine
Purity: 95+%
Packaging: 250mg
Price: $231
Updated: 2021/12/16

AK Scientific

Product number: J50356
Product name: 6-Chloro-N-methyl-5-nitro-4-pyrimidinamine
Packaging: 250mg
Price: $234
Updated: 2021/12/16

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N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINE Chemical Properties,Usage,Production

Synthesis

4316-93-2

74-89-5

23126-82-1

To a stirred solution of 4,6-dichloro-5-nitropyrimidine (1.5 mmol), monomethylamine (0.5 mmol), Pd2(dba)3 (0.01 mmol), R-BINAP (0.03 mmol), and potassium carbonate (0.7 mmol) in toluene (5 mL) was reacted under argon protection for 3.5 hours at room temperature. Upon completion of the reaction, the mixture was filtered and concentrated. The residue was purified by silica gel column chromatography to afford the target product 6-chloro-N-methyl-5-nitro-4-pyrimidinamine.

References

[1] Chinese Chemical Letters, 2017, vol. 28, # 3, p. 583 - 587
[2] Patent: EP1598354, 2005, A1. Location in patent: Page/Page column 90
[3] Journal of Applied Chemistry, 1957, vol. 7, p. 109,112
[4] Journal of the American Chemical Society, 1957, vol. 79, p. 490,493
[5] European Journal of Medicinal Chemistry, 2010, vol. 45, # 8, p. 3389 - 3393

N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINE Suppliers

China 38 Germany 2 India 1 United Kingdom 2 United States 4 Global 47

Shanghai Hanhong Scientific Co.,Ltd.

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23126-82-1, N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINERelated Search:

6-CHLORO-5-NITROPYRIMIDIN-4-AMINE 4-(6-CHLORO-5-NITRO-4-PYRIMIDINYL)-1-PIPERAZINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER 4-CHLORO-6-(4-METHYL-1-PIPERAZINYL)-5-NITROPYRIMIDINE IFLAB-BB F2124-0125 IFLAB-BB F2124-0130 N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINE 1-(6-CHLORO-5-NITRO-4-PYRIMIDINYL)-1,2,3,4-TETRAHYDROQUINOLINE IFLAB-BB F2124-0139 IFLAB-BB F2124-0138 4-CHLORO-5-NITRO-6-(1-PYRROLIDINYL)PYRIMIDINE IFLAB-BB F2124-0140 N-benzyl-6-chloro-5-nitro-4-pyrimidinamine IFLAB-BB F2124-0124 IFLAB-BB F2124-0129 6-CHLORO-N-ETHYL-5-NITRO-2-(TRIFLUOROMETHYL)PYRIMIDIN-4-AMINE AKOS BBS-00003136 IFLAB-BB F2124-0135 6-CHLORO-N-ISOPROPYL-5-NITRO-2-(TRIFLUOROMETHYL)PYRIMIDIN-4-AMINE

6-Chloro-N-methyl-5-nitro-4-pyrimidinamine

N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINE

AKOS BBS-00003135

4-Pyrimidinamine, 6-chloro-N-methyl-5-nitro-

23126-82-1