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RO495

Product Name
RO495
CAS No.
1258296-60-4
Chemical Name
RO495
Synonyms
RO495;CS-2667;RO495/RO-495;RO495 ,S0384;RO495 (CS-2667);RO495, 10 mM in DMSO;RO495 (TYK Tool 1);Janus kinase,Inhibitor,inhibit,RO 495,RO495,JAK,RO-495;N-[2-[(2-Amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl]-2,6-dichlorobenzamide;N-(2-((2-amino-6-methylpyrimidin-4-yl)amino)pyridin-4-yl)-2,6-dichlorobenzamide
CBNumber
CB72621147
Molecular Formula
C17H14Cl2N6O
Formula Weight
389.24
MOL File
1258296-60-4.mol
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RO495 Property

Density 
1.517±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 78 mg/mL (200.39 mM);Ethanol: Insoluble
pka
10.48±0.70(Predicted)
form 
Solid
color 
Light yellow to yellow
Water Solubility 
Water: Insoluble
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Adipogen Life Sciences
Product number
SYN-1128-M001
Product name
RO495
Purity
≥95%
Packaging
1mg
Price
$211
Updated
2021/12/16
Adipogen Life Sciences
Product number
SYN-1128-M010
Product name
RO495
Purity
≥95%
Packaging
10mg
Price
$751
Updated
2021/12/16
AK Scientific
Product number
SYN1128
Product name
RO495
Packaging
50mg
Price
$2000
Updated
2021/12/16
Adipogen Life Sciences
Product number
SYN-1128-M050
Product name
RO495
Purity
≥95%
Packaging
50mg
Price
$2138
Updated
2021/12/16
DC Chemicals
Product number
DC8528
Product name
RO495
Purity
>98%
Packaging
1g
Price
$2200
Updated
2021/12/16
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RO495 Chemical Properties,Usage,Production

Uses

RO495 is a potent inhibitor of non-receptor tyrosine-protein kinase 2 (TYK2 kinase)[1].

References

[1] Tobie D. Lee, et al. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology November 2019, 96 (5) 629-640. DOI:10.1124/mol.119.115964

RO495 Preparation Products And Raw materials

Raw materials

Preparation Products

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RO495 Suppliers

Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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+86-25-83453306
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info@chemlin.com.cn
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China
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SYN|thesis med chem P/L
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+86-021-50720296
Fax
+86-021-50720297
Email
service@synkinase.com
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China
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LETOPHARM LIMITED
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+86-21-5821 5861
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021-52996696,15000506266 15000506266
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+86-21-52996696
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1258296-60-4, RO495Related Search:


  • RO495
  • RO495/RO-495
  • RO495 (TYK Tool 1)
  • CS-2667
  • Benzamide, N-[2-[(2-amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl]-2,6-dichloro-
  • N-(2-((2-amino-6-methylpyrimidin-4-yl)amino)pyridin-4-yl)-2,6-dichlorobenzamide
  • RO495 (CS-2667)
  • Janus kinase,Inhibitor,inhibit,RO 495,RO495,JAK,RO-495
  • RO495, 10 mM in DMSO
  • RO495 ,S0384
  • N-[2-[(2-Amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl]-2,6-dichlorobenzamide
  • 1258296-60-4
  • 258296-60-4
  • C17H14Cl2N6O