ROC-325

Product Name: ROC-325
CAS No.: 1859141-26-6
Chemical Name: ROC-325
Synonyms: ROC-325;ROC325;ROC 325;ROC-325 ，S8527;ROC-325, 10 mM in DMSO;1-((2-((2-((7-Chloroquinolin-4-yl)amino)ethyl)(methyl)amino)ethyl)amino)-4-methyl-9H-thioxanthen-9-one;9H-Thioxanthen-9-one, 1-[[2-[[2-[(7-chloro-4-quinolinyl)amino]ethyl]methylamino]ethyl]amino]-4-methyl-;Apoptosis,anticancer,inhibit,Autophagosomes,cathepsin-D,lysosomes,ROC 325,ROC-325,ROC325,oral,Autophagy,Inhibitor
CBNumber: CB23339912
Molecular Formula: C28H27ClN4OS
Formula Weight: 503.06
MOL File: 1859141-26-6.mol

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ROC-325 Property

Boiling point:: 726.0±60.0 °C(Predicted)
Density: 1.344±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Chloroform: 10 mg/ml; DMF: slightly soluble; DMSO: slightly soluble; Ethanol: slightly soluble
form: A solid
pka: 8.36±0.50(Predicted)
color: Light yellow to orange
InChIKey: HXUYKEGAEIYPKY-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C=CC=C2)SC2=C1C(NCCN(CCNC1=C3C(=NC=C1)C=C(Cl)C=C3)C)=CC=C2C

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: R639505
Product name: ROC325
Packaging: 2.5mg
Price: $180
Updated: 2021/12/16

Ambeed

Product number: A461073
Product name: ROC-325
Purity: 98+%
Packaging: 5mg
Price: $74
Updated: 2021/12/16

Ambeed

Product number: A461073
Product name: ROC-325
Purity: 98+%
Packaging: 10mg
Price: $111
Updated: 2021/12/16

Ambeed

Product number: A461073
Product name: ROC-325
Purity: 98+%
Packaging: 25mg
Price: $200
Updated: 2021/12/16

Ambeed

Product number: A461073
Product name: ROC-325
Purity: 98+%
Packaging: 50mg
Price: $320
Updated: 2021/12/16

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ROC-325 Chemical Properties,Usage,Production

Uses

ROC 325, is a novel inhibitor of autophagy. It triggers an increase in cathepsin D (CTSD) levels.

in vivo

Oral administration of ROC-325 (25 mg/kg, 40 mg/kg, 50 mg/kg,) to mice bearing 786-0 RCC xenografts is well tolerated, significantly more effective at inhibiting tumor progression than Hydroxychloroquine, and inhibits autophagy in vivo^[1].

ROC-325 Preparation Products And Raw materials

Raw materials

Preparation Products

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ROC-325 Suppliers

China 54 India 1 United States 6 Global 61

ShangHai ChuanQian Chemcial Technique Centre

Tel: 15869524721
Email: 3525679403@qq.com
Country: China
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Chembest Research Laboratories Limited

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Email: sales@BioChemBest.com
Country: China
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ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Beijing Solarbio Science & Tecnology Co., Ltd.

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Country: China
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Zhaoqing Wanwei New Material Technology Co., Ltd.

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Email: 13288804488@163.com
Country: China
ProdList: 625
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Angel Pharmatech, Ltd.

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Country: China
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Guangzhou Tomums Life Science Co., Ltd.

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Taizhou Crene Biotechnology Co. Ltd.

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ProdList: 1991
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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1859141-26-6, ROC-325Related Search:

Ro 3306 Bisindoylmaleimide X RO495 3,4-difluoro-2-(2-fluoro-4-iodophenylaMino)-N-(2-hydroxyethoxy)-5-((3-oxoMorpholino)Methyl)benzaMide 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide RO2959 Hydrochloride (S)-2-(4-(2-chlorophenoxy)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(1-((S)-2,3-dihydroxypropyl)-1H-pyrazol-3-yl)-4-methylpentanamide

ROC-325

ROC325;ROC 325

9H-Thioxanthen-9-one, 1-[[2-[[2-[(7-chloro-4-quinolinyl)amino]ethyl]methylamino]ethyl]amino]-4-methyl-

1-((2-((2-((7-Chloroquinolin-4-yl)amino)ethyl)(methyl)amino)ethyl)amino)-4-methyl-9H-thioxanthen-9-one

Apoptosis,anticancer,inhibit,Autophagosomes,cathepsin-D,lysosomes,ROC 325,ROC-325,ROC325,oral,Autophagy,Inhibitor

ROC-325, 10 mM in DMSO

ROC-325 ，S8527

1859141-26-6