ChemicalBook > CAS DataBase List > 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
- Product Name
- 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
- CAS No.
- 199666-03-0
- Chemical Name
- 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
- Synonyms
- CS-1828;R061-8048;Ro 61-8048, >=98%;Ro 61-8048 >=98% (HPLC);KMO Inhibitor I, Ro 61-8048;KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem;3,4-Dimethoxy-N-4-(3-nitro-phenyl)-thiazol-2-yl-benzenesulfomide;3,4-diMethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonaMide;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide;Benzenesulfonamide, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]-
- CBNumber
- CB61458468
- Molecular Formula
- C17H15N3O6S2
- Formula Weight
- 421.45
- MOL File
- 199666-03-0.mol
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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Property
- Melting point:
- 185℃
- Boiling point:
- 627.4±65.0 °C(Predicted)
- Density
- 1.471±0.06 g/cm3 (20 ºC 760 Torr)
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥15mg/mL
- pka
- 6.29±0.10(Predicted)
- form
- Yellow solid
- color
- faint yellow to yellow
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML0233
- Product name
- Ro 61-8048
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $132
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 420360-M
- Product name
- KMO Inhibitor I, Ro 61-8048
- Packaging
- 10mg-m
- Price
- $135
- Updated
- 2021/12/16
Sigma-Aldrich
- Product number
- 420360-M
- Product name
- KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem
- Packaging
- 10mg
- Price
- $135
- Updated
- 2021/12/16
Cayman Chemical
- Product number
- 15199
- Product name
- Ro 61-8048
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $81
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 15199
- Product name
- Ro 61-8048
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $112
- Updated
- 2024/03/01
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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Chemical Properties,Usage,Production
Uses
Ro 61-8048 is a potent and competitive kynurenine 3-monooxygenase (KMO) inhibitor.
Definition
ChEBI: Ro 61-8048 is a C-nitro compound.
Biological Activity
Potent and competitive kynurenine 3-hydroxylase inhibitor (K i = 4.8 nM, IC 50 = 37 nM). Increases kynurenic acid levels to concentrations that antagonize the glycine site of NMDA receptors. Brain penetrant and exhibits antidystonic, anticonvulsant and neuroprotective activities.
Biochem/physiol Actions
Ro 61-8048 is an inhibitor of kynurenine 3-monooxygenase (KMO) that increases kynurenic acid levels and reduces extracellular glutamate in the brain.
storage
+4°C
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Preparation Products And Raw materials
Raw materials
Preparation Products
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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Suppliers
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View Lastest Price from 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide manufacturers
Career Henan Chemical Co
- Product
- 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide 199666-03-0
- Price
- US $1.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 98%
- Supply Ability
- 10kg
- Release date
- 2019-09-04
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