ASP 2151

ChemicalBook > CAS DataBase List > ASP 2151

Product Name: ASP 2151
CAS No.: 841301-32-4
Chemical Name: ASP 2151
Synonyms: CS-2753;ASP 2151;Amcnamevir;AMenaMevir;Amenamevil;Amenamevir (ASP2151);ASP 2151 (Amenamevir);ASP2151;ASP 2151;ASP-2151;Rosuvastatin Impurity 184;Herpes simplex virus,Amenamevir,Inhibitor,ASP-2151,HSV,ASP 2151,inhibit
CBNumber: CB72627341
Molecular Formula: C24H26N4O5S
Formula Weight: 482.55
MOL File: 841301-32-4.mol

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ASP 2151 Property

Density: 1.360±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF:PBS (pH 7.2) (1:20):0.04(Max Conc. mg/mL);0.08(Max Conc. mM)
DMF:2.0(Max Conc. mg/mL);4.14(Max Conc. mM)
form: A solid
pka: 12.60±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27921
Product name: Amenamevir
Packaging: 1mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 27921
Product name: Amenamevir
Packaging: 25mg
Price: $1652
Updated: 2024/03/01

Cayman Chemical

Product number: 27921
Product name: Amenamevir
Packaging: 5mg
Price: $452
Updated: 2024/03/01

Cayman Chemical

Product number: 27921
Product name: Amenamevir
Packaging: 10mg
Price: $783
Updated: 2024/03/01

TRC

Product number: A576425
Product name: Amenamevir
Packaging: 50mg
Price: $730
Updated: 2021/12/16

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ASP 2151 Chemical Properties,Usage,Production

Description

Amenamevir is an antiviral inhibitor of herpes simplex virus 1 (HSV-1) helicase-primase complex activity. It inhibits recombinant HSV-1 helicase with an IC₅₀ value of 0.078 μM and recombinant HSV-1 primase when used at concentrations greater than or equal to 0.03 μM. Amenamevir inhibits replication of varicella-zoster virus (VZV), HSV-1, and HSV-2 in human embryonic fibroblast (HEF) cells (EC₅₀s = 0.047, 0.036, and 0.028 μM, respectively) and is not cytotoxic to HEF cells with a 50% cytotoxic concentration (CC₅₀) of greater than 30 μM. Amenamevir also inhibits replication of clinical VZV isolates in HEF cells (EC₅₀s = 0.038-0.10 μM). In vivo, it increases survival of cutaneously HSV-1-infected mice in a zosteriform-spread model of progressive HSV-1 infection (ED₅₀ = 1.9 mg/kg twice per day).

Uses

Amenamevir is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC50 of 14 ng/mL.

ASP 2151 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ASP 2151 manufacturers

Shenzhen Excellent Biotech Co., Ltd.

Product: Amenamevir 841301-32-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000KG
Release date: 2020-08-21

Career Henan Chemical Co

Product: ASP 2151 841301-32-4
Price: US $1.00/g
Min. Order: 1g
Purity: 99.99%
Supply Ability: 200kg
Release date: 2019-12-24

841301-32-4, ASP 2151Related Search:

Velpatasvir

ASP 2151

AMenaMevir

N-(2,6-Dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-2H-thiopyran-4-carboxamide 1,1-dioxide

ASP 2151 (Amenamevir)

CS-2753

ASP2151;ASP 2151;ASP-2151

N-(2,6-Dimethylphenyl)-N-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl] amino}-2-oxoethyl)-1,1-dioxothiane-4-carboxamide

N-(2-((4-(1,2,4-Oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-N-(2,6-dimethylphenyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide

Amenamevir (ASP2151)

2H-Thiopyran-4-carboxamide, N-(2,6-dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-, 1,1-dioxide

Amcnamevir

Herpes simplex virus,Amenamevir,Inhibitor,ASP-2151,HSV,ASP 2151,inhibit

Amenamevil

Rosuvastatin Impurity 184

(2E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-Propenoic acid 1-methylethyl ester

841301-32-4