ChemicalBook > CAS DataBase List > ASP 2151

ASP 2151

Product Name
ASP 2151
CAS No.
841301-32-4
Chemical Name
ASP 2151
Synonyms
CS-2753;ASP 2151;Amcnamevir;AMenaMevir;Amenamevil;Amenamevir (ASP2151);ASP 2151 (Amenamevir);ASP2151;ASP 2151;ASP-2151;Rosuvastatin Impurity 184;Herpes simplex virus,Amenamevir,Inhibitor,ASP-2151,HSV,ASP 2151,inhibit
CBNumber
CB72627341
Molecular Formula
C24H26N4O5S
Formula Weight
482.55
MOL File
841301-32-4.mol
More
Less

ASP 2151 Property

Density 
1.360±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF:PBS (pH 7.2) (1:20):0.04(Max Conc. mg/mL);0.08(Max Conc. mM)
DMF:2.0(Max Conc. mg/mL);4.14(Max Conc. mM)
form 
A solid
pka
12.60±0.70(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
27921
Product name
Amenamevir
Packaging
1mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
27921
Product name
Amenamevir
Packaging
25mg
Price
$1652
Updated
2024/03/01
Cayman Chemical
Product number
27921
Product name
Amenamevir
Packaging
5mg
Price
$452
Updated
2024/03/01
Cayman Chemical
Product number
27921
Product name
Amenamevir
Packaging
10mg
Price
$783
Updated
2024/03/01
TRC
Product number
A576425
Product name
Amenamevir
Packaging
50mg
Price
$730
Updated
2021/12/16
More
Less

ASP 2151 Chemical Properties,Usage,Production

Description

Amenamevir is an antiviral inhibitor of herpes simplex virus 1 (HSV-1) helicase-primase complex activity. It inhibits recombinant HSV-1 helicase with an IC50 value of 0.078 μM and recombinant HSV-1 primase when used at concentrations greater than or equal to 0.03 μM. Amenamevir inhibits replication of varicella-zoster virus (VZV), HSV-1, and HSV-2 in human embryonic fibroblast (HEF) cells (EC50s = 0.047, 0.036, and 0.028 μM, respectively) and is not cytotoxic to HEF cells with a 50% cytotoxic concentration (CC50) of greater than 30 μM. Amenamevir also inhibits replication of clinical VZV isolates in HEF cells (EC50s = 0.038-0.10 μM). In vivo, it increases survival of cutaneously HSV-1-infected mice in a zosteriform-spread model of progressive HSV-1 infection (ED50 = 1.9 mg/kg twice per day).

Uses

Amenamevir is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC50 of 14 ng/mL.

ASP 2151 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ASP 2151 Suppliers

China 60 India 3 United States 7 Global 70
More
Less

View Lastest Price from ASP 2151 manufacturers

Shenzhen Excellent Biotech Co., Ltd.
Product
Amenamevir 841301-32-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000KG
Release date
2020-08-21
Career Henan Chemical Co
Product
ASP 2151 841301-32-4
Price
US $1.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
200kg
Release date
2019-12-24

841301-32-4, ASP 2151Related Search:

Velpatasvir

  • ASP 2151
  • AMenaMevir
  • N-(2,6-Dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-2H-thiopyran-4-carboxamide 1,1-dioxide
  • ASP 2151 (Amenamevir)
  • CS-2753
  • ASP2151;ASP 2151;ASP-2151
  • N-(2,6-Dimethylphenyl)-N-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl] amino}-2-oxoethyl)-1,1-dioxothiane-4-carboxamide
  • N-(2-((4-(1,2,4-Oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-N-(2,6-dimethylphenyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide
  • Amenamevir (ASP2151)
  • 2H-Thiopyran-4-carboxamide, N-(2,6-dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-, 1,1-dioxide
  • Amcnamevir
  • Herpes simplex virus,Amenamevir,Inhibitor,ASP-2151,HSV,ASP 2151,inhibit
  • Amenamevil
  • Rosuvastatin Impurity 184
  • (2E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-Propenoic acid 1-methylethyl ester
  • 841301-32-4