ASP 2151
- Product Name
- ASP 2151
- CAS No.
- 841301-32-4
- Chemical Name
- ASP 2151
- Synonyms
- CS-2753;ASP 2151;Amcnamevir;AMenaMevir;Amenamevil;Amenamevir (ASP2151);ASP 2151 (Amenamevir);ASP2151;ASP 2151;ASP-2151;Rosuvastatin Impurity 184;Herpes simplex virus,Amenamevir,Inhibitor,ASP-2151,HSV,ASP 2151,inhibit
- CBNumber
- CB72627341
- Molecular Formula
- C24H26N4O5S
- Formula Weight
- 482.55
- MOL File
- 841301-32-4.mol
ASP 2151 Property
- Density
- 1.360±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF:PBS (pH 7.2) (1:20):0.04(Max Conc. mg/mL);0.08(Max Conc. mM)
DMF:2.0(Max Conc. mg/mL);4.14(Max Conc. mM) - form
- A solid
- pka
- 12.60±0.70(Predicted)
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 27921
- Product name
- Amenamevir
- Packaging
- 1mg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 27921
- Product name
- Amenamevir
- Packaging
- 25mg
- Price
- $1652
- Updated
- 2024/03/01
- Product number
- 27921
- Product name
- Amenamevir
- Packaging
- 5mg
- Price
- $452
- Updated
- 2024/03/01
- Product number
- 27921
- Product name
- Amenamevir
- Packaging
- 10mg
- Price
- $783
- Updated
- 2024/03/01
- Product number
- A576425
- Product name
- Amenamevir
- Packaging
- 50mg
- Price
- $730
- Updated
- 2021/12/16
ASP 2151 Chemical Properties,Usage,Production
Description
Amenamevir is an antiviral inhibitor of herpes simplex virus 1 (HSV-1) helicase-primase complex activity. It inhibits recombinant HSV-1 helicase with an IC50 value of 0.078 μM and recombinant HSV-1 primase when used at concentrations greater than or equal to 0.03 μM. Amenamevir inhibits replication of varicella-zoster virus (VZV), HSV-1, and HSV-2 in human embryonic fibroblast (HEF) cells (EC50s = 0.047, 0.036, and 0.028 μM, respectively) and is not cytotoxic to HEF cells with a 50% cytotoxic concentration (CC50) of greater than 30 μM. Amenamevir also inhibits replication of clinical VZV isolates in HEF cells (EC50s = 0.038-0.10 μM). In vivo, it increases survival of cutaneously HSV-1-infected mice in a zosteriform-spread model of progressive HSV-1 infection (ED50 = 1.9 mg/kg twice per day).
Uses
Amenamevir is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC50 of 14 ng/mL.
ASP 2151 Preparation Products And Raw materials
Raw materials
Preparation Products
ASP 2151 Suppliers
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View Lastest Price from ASP 2151 manufacturers
- Product
- ASP 2151 841301-32-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- kg
- Release date
- 2024-10-14
- Product
- Amenamevir 841301-32-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5000KG
- Release date
- 2020-08-21
- Product
- ASP 2151 841301-32-4
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.99%
- Supply Ability
- 200kg
- Release date
- 2019-12-24