ChemicalBook > CAS DataBase List > 2,4-DIFLUOROPYRIMIDINE
2,4-DIFLUOROPYRIMIDINE
Synthesis- Product Name
- 2,4-DIFLUOROPYRIMIDINE
- CAS No.
- 2802-61-1
- Chemical Name
- 2,4-DIFLUOROPYRIMIDINE
- Synonyms
- EOS-61621;NSC 331813;2,4-DIFLUOROPYRIMIDINE;2,4-DIFLUOROPYRIMMIDINE;Pyrimidine, 2,4-difluoro-;2,4-Difluoropyrimidine98%;2,4-Difluoropyrimidine 98%;2,4-Difluoropyrimidine;Pyrimidine, 2,4-difluoro- (6CI,8CI,9CI);2,4-DIFLUOROPYRIMIDINE ISO 9001：2015 REACH
- CBNumber
- CB7263268
- Molecular Formula
- C4H2F2N2
- Formula Weight
- 116.07
- MOL File
- 2802-61-1.mol
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2,4-DIFLUOROPYRIMIDINE Property
- Boiling point:
- 118-120 °C
- Density
- 1.359 g/mL at 25 °C
- refractive index
- n20/D 1.432
- Flash point:
- 106 °F
- pka
- -2.52±0.20(Predicted)
- form
- liquid
- color
- Clear, colourless
- CAS DataBase Reference
- 2802-61-1(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 10-22-37/38-41
- Safety Statements
- 26-39
- RIDADR
- UN 1993 3/PG 3
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 3
- PackingGroup
- III
- HS Code
- 29335990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 661082
- Product name
- 2,4-Difluoropyrimidine
- Purity
- 97%
- Packaging
- 500mg
- Price
- $161
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- 661082
- Product name
- 2,4-Difluoropyrimidine
- Purity
- 97%
- Packaging
- 100mg
- Price
- $53.6
- Updated
- 2023/01/07
TRC
- Product number
- D448643
- Product name
- 2,4-Difluoropyrimidine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 018269
- Product name
- 2,4-Difluoropyrimidine
- Purity
- 95%
- Packaging
- 1g
- Price
- $52
- Updated
- 2021/12/16
Apolloscientific
- Product number
- PC1056
- Product name
- 2,4-Difluoropyrimidine
- Purity
- 98%
- Packaging
- 1g
- Price
- $67
- Updated
- 2021/12/16
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2,4-DIFLUOROPYRIMIDINE Chemical Properties,Usage,Production
Synthesis
Crown ethers are able to enhance the performance of KF in two ways. Firstly,
they complex the potassium cation making a better fluoride source and secondly they
increase the solubility of KF in the solvent.
KF with a catalytic amount of dicyclohexano-18-crown-6 in tetraglyme converted
2,4-dichloropyrimidine into 2,4-difluoropyrimidine.
Uses
2,4-Difluoropyrimidine can be used as a starting material to synthesize:
- 3-Pyrimidin-4-yl-oxazolidin-2-one derivatives as mutant isocitrate dehydrogenase (IDH1) inhibitors.
- N,N′-(1,4-phenylenebis(methylene))bis(2-fluoropyrimidin-4-amine) as chemokine receptor type 4 antagonists.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 22, p. 149, 1985 DOI: 10.1002/jhet.5570220137
2,4-DIFLUOROPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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2,4-DIFLUOROPYRIMIDINE Suppliers
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View Lastest Price from 2,4-DIFLUOROPYRIMIDINE manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- 2,4-DIFLUOROPYRIMIDINE 2802-61-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26
Career Henan Chemical Co
- Product
- 2,4-DIFLUOROPYRIMIDINE 2802-61-1
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-09
2802-61-1, 2,4-DIFLUOROPYRIMIDINERelated Search:
5-chloro-2,4-difluoropyrimidine
2-ETHOXY-4,6-DIFLUOROPYRIMIDINE
2-MORPHOLINO-4,6-DIFLUOROPYRIMIDINE,98%
2,5-Difluoropyridine
3,5-Difluoropyridine
3,5-Difluoropyridine-2,6-diamine
5-BROMO-2,4-DIFLUOROPYRIMIDINE
4-AMINO-2,6-DIFLUOROPYRIMIDINE
5-Chloro-2,4,6-trifluoropyrimidine
2,4,6-TRIFLUOROPYRIMIDINE
2,4-DIFLUOROPYRIMIDINE
5-Chloro-2,3-difluoropyridine
2-AMINO-4,6-DIFLUOROPYRIMIDINE
4-Amino-3,5-dichloro-2,6-difluoropyridine
2,3-Difluoropyridine
2,6-Difluoropyridine-3-boronic acid
3,5-DICHLORO-2,6-DIFLUOROPYRIDINE
4-Pyrimidinamine,2,6-difluoro-N-methyl-